Searched for: subject:"MSB%5C+%5C-%5C+Microbiology%5C+and%5C+Systems%5C+Biology%5C+RAPID%5C+%5C-%5C+Risk%5C+Analysis%5C+for%5C+Products%5C+in%5C+Development"
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Pantophlet, A.J. (author), Wopereis, S. (author), Eelderink, C. (author), Vonk, R.J. (author), Stroeve, J.H. (author), Bijlsma, S. (author), van Stee, L. (author), Bobeldijk, I. (author), Priebe, M.G. (author)
Background: The consumption of products rich in cereal fiber and with a low glycemic index is implicated in a lower risk of metabolic diseases. Previously, we showed that the consumption of fiber-rich pasta compared with bread resulted in a lower rate of appearance of exogenous glucose and a lower glucose clearance rate quantified with a dual...
article 2017
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Broekman, H. (author), Knulst, A. (author), den Hartog Jager, S. (author), Monteleone, F. (author), Gaspari, M. (author), de Jong, G. (author), Houben, G. (author), Verhoeckx, K. (author)
Scope: The growing world population requires the exploration of new sustainable protein sources to ensure food security. Insects such as mealworm are promising candidates. For safety reasons, a risk assessment, including allergy risks, is needed. Since allergenicity can be influenced by thermal processing, it is highly important to take this...
article 2015
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van de Steeg, E. (author), Venhorst, J. (author), Jansen, H.T. (author), Nooijen, I.H.G. (author), Degroot, J. (author), Wortelboer, H.M. (author), Vlaming, M.L.H. (author)
Human organic anion-transporting polypeptide 1B1 (OATP1B1) and OATP1B3 are important hepatic uptake transporters. Early assessment of OATP1B1/1B3-mediated drug-drug interactions (DDIs) is therefore important for successful drug development. A promising approach for early screening and prediction of DDIs is computational modeling. In this study...
article 2015
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Gierman, L.M. (author), Wopereis, S. (author), van El, B. (author), Verheij, E.R. (author), Werff-Van Der Vat, B.J.C. (author), Bastiaansen-Jenniskens, Y.M. (author), van Osch, G.J.V.M. (author), Kloppenburg, M. (author), Stojanovic-Susulic, V. (author), Huizinga, T.W.J. (author), Zuurmond, A.M. (author)
Objective The infrapatellar fat pad (IPFP) in the knee joint is hypothesized to contribute to osteoarthritis (OA) development by the IFPF possibly by influencing inflammatory processes. Oxylipins are essential mediators in the inflammatory process. We undertook this study to investigate secretion by the IFPF of fatty acids and oxylipins derived...
article 2013
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Pasman, W.J. (author), van Erk, M.J. (author), Klöpping, W.A.A. (author), Pellis, L. (author), Wopereis, S. (author), Bijlsma, S. (author), Hendriks, H.F.J. (author), Kardinaal, A.F.M. (author)
We aimed to explore whether vegetable consumption according to guidelines has beneficial health effects determined with classical biomarkers and nutrigenomics technologies. Fifteen lean (age 36 ± 7 years; BMI 23.4 ± 1.7 kg m−2) and 17 obese (age 40 ± 6 years; BMI 30.3 ± 2.4 kg m−2) men consumed 50- or 200-g vegetables for 4 weeks in a randomized...
article 2013
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Wei, H. (author), Hu, C. (author), Wang, M. (author), van den Hoek, A.M. (author), Reijmers, T.H. (author), Wopereis, S. (author), Bouwman, J. (author), Ramaker, R. (author), Korthout, H.A.A.J. (author), Vennik, M. (author), Hankemeier, T. (author), Havekes, L.M. (author), Witkamp, R.F. (author), Verheij, E.R. (author), Xu, G. (author), van der Greef, J. (author)
Background: Causes and consequences of the complex changes in lipids occurring in the metabolic syndrome are only partly understood. Several interconnected processes are deteriorating, which implies that multi-target approaches might be more successful than strategies based on a limited number of surrogate markers. Preparations from Chinese...
article 2012
Searched for: subject:"MSB%5C+%5C-%5C+Microbiology%5C+and%5C+Systems%5C+Biology%5C+RAPID%5C+%5C-%5C+Risk%5C+Analysis%5C+for%5C+Products%5C+in%5C+Development"
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