Searched for: subject%3A%22MSB%255C%2B%255C-%255C%2BMicrobiology%255C%2Band%255C%2BSystems%255C%2BBiology%255C%2BPHS%255C%2B%255C-%255C%2BPharmacokinetics%255C%2B%2526%255C%2BHuman%255C%2BStudies%22
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Roeselers, G. (author), Ponomarenko, M. (author), Lukovac, S. (author), Wortelboer, H.M. (author)
It is increasingly apparent that the microbial ecosystems in the mammalian gastrointestinal tract play an intricate role in health and disease. There is a growing interest in the development of targeted strategies for modulating health through the modification of these microbiota. Ecologists are faced with the challenge of understanding the...
article 2013
document
Clabbers, N. (author), van Dijken, P. (author), van Gool, A. (author), van der Greef, J. (author), de Groot, J. (author), Hendriks, H. (author), van Meeteren, N. (author), Mooij, R. (author), van Ommen, B. (author), Rietkerk, O. (author), Snoeij, N. (author), van Staalduinen, W. (author), Stadlander, M. (author), Wevers, C. (author), Wieringa, F. (author)
report 2013
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Wopereis, S. (author), Wolvers, D. (author), van Erk, M.J. (author), Gribnau, M. (author), Kremer, S.H.A. (author), van Dorsten, F.A. (author), Boelsma, E. (author), Garczarek, U. (author), Cnubben, N. (author), Frenken, L. (author), der Logt P, van (author), Hendriks, H.F. (author), Albers, R. (author), van Duynhoven, J. (author), van Ommen, B. (author), Jacobs, D.M. (author)
Background: Resilience or the ability of our body to cope with daily-life challenges has been proposed as a new definition of health, with restoration of homeostasis as target resultant of various physiological stress responses. Challenge models may thus be a sensitive measure to study the body’s health. The objective of this study was to select...
article 2013
document
Roeselers, G. (author), Bouwman, J. (author), Venema, K. (author), Montijn, R. (author)
The mammalian gastrointestinal tract (GIT) harbors microorganisms (the microbiota) of vast phylogentic, genomic, and metabolic diversity, and recent years have seen a rapid development in the techniques for studying these complex microbial ecosystems. It is increasingly apparent that the GIT microbiota plays an intricate role in host health and...
article 2012
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Balvers, M.G.J. (author), Verhoeckx, K.C.M. (author), Wortelboer, H.M. (author), Bijlsma, S. (author), Rubingh, C.M. (author), Meijerink, J. (author), Witkamp, R.F. (author)
It is well established that dietary intake of n-3 fatty acids is associated with anti-inflammatory effects, and this has been linked to modulation of the oxylipin and endocannabinoid metabolomes. However, the amount of data on specific tissue effects is limited, and it is not known how inflammation affects this relation. In the present study we...
article 2012
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Rubingh, C.M. (author), van Erk, M.J. (author), Wopereis, S. (author), van Vliet, T. (author), Verheij, E.R. (author), Cnubben, N.H.P. (author), van Ommen, B. (author), van der Greef, J. (author), Hendriks, H.F.J. (author), Smilde, A.K. (author)
Many benefits can be gained if multi-factorial diseases with a high incidence and prevalence are better understood. Sophisticated approaches like multilevel analyses are needed to discover subtle differences between healthy people and people at the onset of disease in these types of studies. Multilevel analysis generates different sub-models for...
article 2011
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