Searched for: subject:"MSB%5C%2B%5C-%5C%2BMicrobiology%5C%2Band%5C%2BSystems%5C%2BBiology%5C%2BQS%5C%2B%5C-%5C%2BQuality%5C%2B%26%5C%2BSafety"
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van der Greef, J. (author), van Wietmarschen, H. (author), van Ommen, B. (author), Verheij, E.R. (author)
Metabolites have played an essential role in our understanding of life, health, and disease for thousands of years. This domain became much more important after the concept of metabolism was discovered. In the 1950s, mass spectrometry was coupled to chromatography and made the technique more application-oriented and allowed the development of...
article 2013
document
Bouwman, J. (author), Vogels, J.T.W.E. (author), Wopereis, S. (author), Rubingh, C.M. (author), Bijlsma, S. (author), van Ommen, B. (author)
Background: Being able to visualize multivariate biological treatment effects can be insightful. However the axes in visualizations are often solely defined by variation and thus have no biological meaning. This makes the effects of treatment difficult to interpret. Methods: A statistical visualization method is presented, which analyses and...
article 2012
document
Zha, Y. (author), Muilwijk, B. (author), Coulier, L.C. (author), Punt, P.J. (author)
To compare the composition and performance of various lignocellulosic biomass hydrolysates as fermentation media, 8 hydrolysates were generated from a grass-like and a wood biomass. The hydrolysate preparation methods used were 1) dilute acid, 2) mild alkaline, 3) alkaline/peracetic acid, and 4) concentrated acid. These hydrolysates were...
article 2012
document
Beker-van Woudenberg, A.C.R.L. (author), Gröllers-Mulderij, M. (author), Snel, C. (author), Jeurissen, N. (author), Stierum, R. (author), Wolterbeek, A. (author)
Reproductive toxicity testing according to the present guidelines requires a high number of animals. Therefore, the development of alternative in vitro methods is urgently required. The aim of the present study was to investigate the applicability domain of the bovine oocyte in vitro maturation assay (bIVM) to study female reproductive...
article 2012
document
Braaksma, M. (author), Bijlsma, S. (author), Coulier, L. (author), Punt, P.J. (author), van der Werf, M.J. (author)
For the optimization of microbial production processes, the choice of the quantitative phenotype to be optimized is crucial. For instance, for the optimization of product formation, either product concentration or productivity can be pursued, potentially resulting in different targets for strain improvement. The choice of a quantitative...
article 2011
Searched for: subject:"MSB%5C%2B%5C-%5C%2BMicrobiology%5C%2Band%5C%2BSystems%5C%2BBiology%5C%2BQS%5C%2B%5C-%5C%2BQuality%5C%2B%26%5C%2BSafety"
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