Searched for: subject:"MSB%5C%2B%5C-%5C%2BMicrobiology%5C%2Band%5C%2BSystems%5C%2BBiology%5C%2BQS%5C%2B%5C-%5C%2BQuality%5C%2B%26%5C%2BSafety"
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Krishnan, S. (author), Verheij, E.E.R. (author), Bas, R.C. (author), Hendriks, M.W.B. (author), Hankemeier, T. (author), Thissen, U. (author), Coulier, L. (author)
RATIONALE Mass spectra obtained by deconvolution of liquid chromatography/high-resolution mass spectrometry (LC/HRMS) data can be impaired by non-informative mass-over-charge (m/z) channels. This impairment of mass spectra can have significant negative influence on further post-processing, like quantification and identification. METHODS A metric...
article 2013
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Zha, Y. (author), Muilwijk, B. (author), Coulier, L.C. (author), Punt, P.J. (author)
To compare the composition and performance of various lignocellulosic biomass hydrolysates as fermentation media, 8 hydrolysates were generated from a grass-like and a wood biomass. The hydrolysate preparation methods used were 1) dilute acid, 2) mild alkaline, 3) alkaline/peracetic acid, and 4) concentrated acid. These hydrolysates were...
article 2012
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Krishnan, S. (author), Vogels, J.T.W.E. (author), Coulier, L. (author), Bas, R.C. (author), Hendriks, M.W.B. (author), Hankemeier, T. (author), Thissen, U. (author)
Setting appropriate bin sizes to aggregate hyphenated high-resolution mass spectrometry data, belonging to similar mass over charge (m/. z) channels, is vital to metabolite quantification and further identification. In a high-resolution mass spectrometer when mass accuracy (ppm) varies as a function of molecular mass, which usually is the case...
article 2012
document
Braaksma, M. (author), Bijlsma, S. (author), Coulier, L. (author), Punt, P.J. (author), van der Werf, M.J. (author)
For the optimization of microbial production processes, the choice of the quantitative phenotype to be optimized is crucial. For instance, for the optimization of product formation, either product concentration or productivity can be pursued, potentially resulting in different targets for strain improvement. The choice of a quantitative...
article 2011
Searched for: subject:"MSB%5C%2B%5C-%5C%2BMicrobiology%5C%2Band%5C%2BSystems%5C%2BBiology%5C%2BQS%5C%2B%5C-%5C%2BQuality%5C%2B%26%5C%2BSafety"
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