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Tuin, A.W. (author), Grotenbreg, G.M. (author), Spalburg, E. (author), de Neeling, A.J. (author), Mars-Groenendijk, R.H. (author), Noort, D. (author), van der Marel, G.A. (author), Overkleeft, H.S. (author), Overhand, M. (author), TNO Defensie en Veiligheid (author)
Loloatin C is a cyclic cationic antimicrobial peptide which is active against Gram positive as well as certain Gram negative bacteria. Unfortunately, it is equally potent against human erythrocytes. To probe the structure-activity relationship of this promising antibiotic peptide, amino acid substitution and/or incorporation of a constraint...
article 2009