Searched for: subject:"Liver%5C+metastasis"
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Rothbarth, J. (author), Woutersen, R.A. (author), Sparidans, R.W. (author), van de Velde, C.J.H. (author), Mulder, G.J. (author)
The optimum conditions (duration and concentration) of a fixed dose, intra-arterial melphalan infusion in relation to its antitumor effect and toxicity in the liver were investigated in a rat colon tumor model (CC531) of liver metastases. We studied the difference in tumor and liver uptake, as well as antitumor effect and hepatotoxicity after 5-...
article 2003
Geutskens, S.B. (author), van der Eb, M.M. (author), Plomp, A.C. (author), Jonges, L.E. (author), Cramer, S.J. (author), Ensink, N.G. (author), Kuppen, P.J.K. (author), Hoeben, R.C. (author)
The host-immune response against adenoviruses forms a major obstacle for their use as gene therapy vectors for treatment of genetic defects. None the less, they are the preferred vectors for in vivo gene transfer in experimental gene therapy protocols for cancer. In this article we demonstrate the antitumor efficacy of adenovirus-mediated...
article 2000