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de Bruin-Hoegée, J.M. (author), Lamriti, L. (author), Langenberg, J.P. (author), Olivier, R.C.M. (author), Chau, L.F. (author), van der Schans, M.J. (author), Noort, D. (author), van Asten, A.C. (author)The continuing threats of military conflicts and terrorism may involve the misuse of chemical weapons. The present study aims to use environmental samples to find evidence of the release of such agents at an incident scene. A novel approach was developed for identifying protein adducts in plants. Basil (Ocimum basilicum), bay laurel leaf (Laurus...article 2023
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Hamzah, N. (author), Höjer Holmgren, K. (author), Åstot, C. (author), van der Schans, M.J. (author), de Reuver, L.P.J. (author), Vanninen, P. (author)The formation of chlorinated organic compounds in concrete debris exposed to reactive chlorine was studied to search for markers specific to chlorine gas exposure. Concrete materials of different origins were exposed to a range of species of reactive chlorine including bleach, humid and dry chlorine gas at different concentrations. Chlorinated...article 2023
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Fratric, P. (author), Sileno, G. (author), Klous, S. (author), van Engers, T. (author)Fraudulent actions of a trader or a group of traders can cause substantial disturbance to the market, both directly influencing the price of an asset or indirectly by misinforming other market participants. Such behavior can be a source of systemic risk and increasing distrust for the market participants, consequences that call for viable...article 2022
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- Massaad, J. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), Sabbadini, A. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author) article 2022
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Massaad, J. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), Pertijs, M.A.P. (author), de Jong, N. (author), Verweij, M.D. (author)Clamp-on ultrasonic flow meters (UFMs) are installed on the outside of the pipe wall. Typically, they consist of two single-element transducers mounted on angled wedges, which are acoustically coupled to the pipe wall. Before flow metering, the transducers are placed at the correct axial position by manually moving one transducer along the pipe...article 2022
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Bodner, S.C. (author), Hlushko, K. (author), van de Vorst, L.T.G. (author), Meindlhumer, M. (author), Todt, J. (author), Nielsen, M.A. (author), Hooijmans, J.W. (author), Saurwalt, J.J. (author), Mirzaei, S. (author), Keckes, J. (author)Additively manufactured multi-metal hybrid structures can be designed as functionally graded materials providing an optimized response at specific positions for particular applications. In this study, liquid dispersed metal powder bed fusion is used to synthesize a multi-metal structure based on Inconel 625 (IN625) and stainless steel 316L ...article 2022
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Massaad, J. (author), van Neer, P.L.M.J. (author), van Willigen, D.M. (author), Sabbadini, A. (author), de Jong, N. (author), Pertijs, M.A.P. (author), Verweij, M.D. (author)Current ultrasonic clamp-on flow meters consist of a pair of single-element transducers which are carefully positioned before use. This positioning process consists of manually finding the distance between the transducer elements, along the pipe axis, for which maximum SNR is achieved. This distance depends on the sound speed, thickness and...article 2021
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van 't Westende, J.M.C. (author), van Nimwegen, A.T. (author), Belfroid, S.P.C. (author), Slot, H.J. (author)Experiments were performed to investigate the physics behind intermittent production and liquid loading, using a setup containing a reservoir model coupled to a vertical production tubing. In the experiments both gas and liquid are injected into the reservoir, which is a container in which sand with two different permeabilities is placed. Quick...conference paper 2021
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Streekstra, E.J. (author), Russel, F.G.M. (author), van de Steeg, E. (author), de Wildt, S.N. (author)Drug disposition in children is different compared to adults. Growth and developmental change the processes involved in drug disposition and efficacy, including membrane transporters and drug metabolizing enzymes, but for many of these proteins, the exact changes have not been fully elucidated to date. Quantitative proteomics offers a solution...article 2021
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Onder, S. (author), van Grol, M. (author), Fidder, A. (author), Xiao, G. (author), Noort, D. (author), Yerramalla, U. (author), Tacal, O. (author), Schopfer, L.M. (author), Lockridge, O. (author)Chronic low-dose exposure to organophosphorus pesticides is associated with the risk of neurodegenerative disease. The mechanism of neurotoxicity is independent of acetylcholinesterase inhibition. Adducts on tyrosine, lysine, threonine, and serine can occur after exposure to organophosphorus pesticides, the most stable being adducts on tyrosine....article 2021
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Kozhevnikov, A. (author), Kunnen, R.P.J. (author), van Baars, G.E. (author), Clercx, H.J.H. (author)The recoating step in stereolithography (SL) is one of the principal sources of inaccuracies. The liquid layer deposition on top of irregular topography leads to a non-uniform layer thickness which eventually results in a poor quality of the final product. To compensate the unevenness of the underlying geometry, an approach where the recoating...article 2020
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Bezemer, K. (author), McLennan, L. (author), van Duin, L. (author), Kuijpers, C.J. (author), Koeberg, M. (author), van den Elshout, J.J.M.H. (author), van der Heijden, A.E.D.M. (author), Busby, T. (author), Yevdokimov, A. (author), Schoenmakers, P. (author), Smith, J. (author), Oxley, J. (author), van Asten, A. (author)Erythritol tetranitrate (ETN) was prepared independently by two research groups from the USA and the Netherlands. The partially nitrated impurities present in ETN were studied using liquid chromatography-mass spectrometry to address the ultimate challenge in forensic explosives investigations, i.e., providing chemical and tactical information on...article 2020
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Franken, R.A. (author), Kasiotis, K.M. (author), Tsakirakis, A.N. (author), Chartzela, I. (author), Anastasiadou, P. (author), Fransman, W. (author), Gerritsen-Ebben, R.M. (author), Spaan, S. (author), Goede, H. (author), Machera, K. (author), Gerritsen-Ebben, R. (author)For many work situations only insufficient exposure data are available to perform proper risk assessment. Because measuring worker exposure can be time consuming and resource intense, the availability of reliable exposure models is important when performing risk assessments. However, the development and improvement of exposure models are...article 2020
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van der Schans, M.J. (author)Chemical warfare agents (CWAs) are the most toxic compounds that have ever been produced. In order to develop medical countermeasures against the effects of these agents, analytical procedures to analyze these agents in their intact form in biological matrices are essential for a better understanding of the toxicological process. Although the...bookPart 2020
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Poort, J.P. (author), Shoeibi Omrani, P.S. (author), Vecchia, A.L. (author)The production optimization of mature gas fields is severely complicated by the occurrence of certain undesired well events such as salt precipitation, liquid loading, or gas/water coning. Learning from production data of periods in which such events have taken place could help operators improve the process optimization. However, due to the...conference paper 2020
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van den Dries, M.A. (author), Guxens, M. (author), Spaan, S. (author), Ferguson, K.K. (author), Philips, E. (author), Santos, S. (author), Jaddoe, V.W.V. (author), Ghassabian, A. (author), Trasande, L. (author), Tiemeier, H. (author), Pronk, A. (author)BACKGROUND: Prenatal exposures to phthalates and bisphenols are associated with impaired brain development in animals. However, epidemiological studies investigating the association between prenatal phthalate or bisphenol exposure and cognition have produced mixed findings and mostly had modest sample sizes and measured the exposure during the...article 2020
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Kelly, J.M. (author), Matuszek, G. (author), van den Broek, T.J. (author), Huggins, G.S. (author), Smith, C.E. (author), Ordovas, J.M. (author), Wopereis, S. (author), Booth, S.L. (author)Inconsistent associations between lipids and circulating markers of fat-soluble vitamin and carotenoid status have been reported. The aim of this hypothesis-generating study was to examine the contribution of the LC-MS-based lipidome, characterized by lipid class, carbon count, and the number of unsaturated bonds, to the interindividual...article 2020
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Bezemer, K. (author), McLennan, L. (author), Hessels, R. (author), Schoorl, J. (author), van den Elshout, J.J.M.H. (author), van der Heijden, A.E.D.M. (author), Hulsbergen, A. (author), Koeberg, M. (author), Busby, T. (author), Yevdokimov, A. (author), Rijke, E. (author), Schoenmakers, P. (author), Smith, J. (author), Oxley, J. (author), van Asten, A. (author)In this follow-up study the collaboration between two research groups from the USA and the Netherlands was continued to expand the framework of chemical attribution for the homemade explosive erythritol tetranitrate (ETN). Isotope ratio mass spectrometry (IRMS) analysis was performed to predict possible links between ETN samples and its...article 2020
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Ndika, J. (author), Ilves, M. (author), Kooter, I.M. (author), Grollers-Mulderij, M. (author), Duistermaat, E. (author), Tromp, P.C. (author), Kuper, F. (author), Kinaret, P. (author), Greco, D. (author), Karisola, P. (author), Alenius, H. (author)The diversity and increasing prevalence of products derived from engineered nanomaterials (ENM), warrants implementation of non-animal approaches to health hazard assessment for ethical and practical reasons. Although non-animal approaches are becoming increasingly popular, there are almost no studies of side-by-side comparisons with traditional...article 2020
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van Beek, P.J.G. (author), González Díez, N. (author), Aardal, P. (author)Flexible corrugated pipes as used for the transport of gas in offshore deepwater applications can generate undesired flow-induced pulsations (FLIP). This phenomenon has been also traditionally called “singing risers”. The pulsations generated may result in high-amplitude cyclic stresses in the pipe systems attached to the flexible. Moreover, an...conference paper 2020