Searched for: subject%3A%22Lipoproteins%22
(261 - 269 of 269)

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Gaubius instituut TNO (author), Havekes, L. (author), van Hinsbergh, V. (author), Kempen, H.J. (author), Emeis, J. (author)
The human hepatoma cell line Hep G2 was studied with respect to metabolism of human low-density lipoprotein (LDL). The Hep G2 cells bind, take up and degrade human LDL with a high-affinity saturable and with a low-affinity non-saturable component. The high-affinity binding possesses a K(D) of 25 nM-LDL and a maximal amount of binding of about 70...
article 1983
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Brommer, E.J.P. (author), Leuven, J.A.G. (author), Barrett-Bergshoeff, M.M. (author), Schouten, J.A. (author), Gaubius instituut TNO (author)
Impairment of fibrinolysis is supposed to contribute to CVD. In 38 hyperlipoproteinemic patients, known to be at risk for early CVD, fibrinolytic activity was measured before and after stimulation with DDAVP. A negative correlation was found between serum triglyceride levels and fibrinolytic activity, both before and after DDAVP. A subnormal...
article 1982
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Emeis, J.J. (author), Vermeer, B.J. (author), Havekes, L. (author), Gaubius instituut TNO (author)
We visualized the apolipoproteins of high density lipoproteins (HDL) that were bound to cultured human fibroblasts at the ultrastructural level, with an immunoenzymecytochemical method. By using antisera against (a) apolipoprotein AI (a major apolipoprotein of HDL) and (b) apolipoprotein E (an apolipoprotein present in HDL), the binding of HDL...
article 1981
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Kremer, J.M.H. (author), Havekes, L. (author), Gaubius instituut TNO (author)
We investigated different procedures to subfractionate high density lipoprotein (HDL) into its density subfractions (HDL2 and HDL3). When pore-limit as well as zone polyacrylamide gel electrophoresis was used, it proved to be necessary to use freshly prepared and plasma protein-free HDL preparations. For a quantitative subfractionation of HDL in...
article 1981
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Gaubius Instituut TNO (author), Havekes, L. (author), Vermeer, B.J. (author), Brugman, T. (author), Emeis, J. (author)
Chemicals/CAS: Lipoprotein(a); Lipoproteins; Lipoproteins, LDL; Receptors, Cell Surface; Receptors, LDL
article 1981
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Havekes, L. (author), Vermeer, B.J. (author), de Wit, E. (author), Gaubius instituut TNO (author)
The suppression of cellular cholesterol synthesis by low density lipoprotein (LDL) from a normal and from a homozygous familial hypercholesterolemic subject was measured on normal fibroblasts and on fibroblasts derived from the same homozygous familial hypercholesterolemic patient. On normal fibroblasts both LDL preparations (density 1.019 to 1...
article 1980
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Gaubius instituut TNO (author), Kempen, H.J.M. (author)
Lipoprotein production by freshly isolated rat hepatocytes in suspension was studied during short (1-3 hr) incubation periods. The heaptocytes release very low density (91.10 g/ml). These particles with higher densities have not been positively identified; the latter group is dissimilar to the high density lipoprotein, which occurs in rat liver...
article 1980
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von Lossonczy, T.O. (author), Ruiter, A. (author), Bronsgeest-Schoute, H.C. (author), van Gent, C.M. (author), Hermus, R.J.J. (author)
A cross-over study was done with 19 male and 23 female volunteers living in a monastery and a convent, respectively. The effect of a fat fish (mackerel) diet on the blood serum lipid composition was studied. As the normal diet of these volunteers was of the lacto-ovo-vegetarian type, a control diet in which the fish was replaced by full-fat...
article 1978
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Brakman, P. (author), Astrup, T. (author), Levy, R.I. (author), Frederickson, D.S. (author), Gezondheidsorganisatie TNO Gaubius Instituut TNO (author)
To correlate resting levels of blood fibrinolysis with different types of hyperlipidemia, the concentrations of fibrinogen and plasminogen and the euglobulin activity (precipitated at pH 5.9 and assayed on fibrin plates prepared with bovine, plasminogen-rich fibrinogen) were determined in fasting plasma samples from a group of normal controls (...
article 1974
Searched for: subject%3A%22Lipoproteins%22
(261 - 269 of 269)

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