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Lee, J.K.W. (author), Tan, B. (author), Kingma, B.R.M. (author), Haman, F. (author), Epstein, Y. (author)Exposure to extreme environmental heat or cold during military activities can impose severe thermal strain, leading to impairments in task performance and increasing the risk of exertional heat (including heat stroke) and cold injuries that can be life-threatening. Substantial individual variability in physiological tolerance to thermal stress...article 2023
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Gayban, A.J.B. (author), Souza, L.A.C. (author), Cooper, S.G. (author), Regalado, E. (author), Kleemann, R. (author), Earley, Y.F. (author)Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum of liver damage directly related to diabetes, obesity, and metabolic syndrome. The (pro)renin receptor (PRR) has recently been demonstrated to play a role in glucose and lipid metabolism. Here, we test the hypothesis that the PRR regulates the development of diet-induced hepatic...article 2023
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Tompa, E. (author), Mofidi, A. (author), van den Heuvel, S. (author), van Bree, T. (author), Michaelsen, F. (author), Jung, Y. (author), Porsch, L. (author), van Emmerik, M. (author)Background. Estimates of the economic burden of work injuries and diseases can help policymakers prioritize occupational health and safety policies and interventions in order to best allocate scarce resources. Several attempts have been made to estimate these economic burdens at the national level, but most have not included a comprehensive list...article 2021
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Kessels, I. (author), Koopman, B. (author), Verdonschot, N. (author), Marra, M. (author), Gijsbertse, K. (author)The performance of military tasks is often exacerbated by additional load carriage, leading to increased physical demand. Previous studies showed that load carriage may lead to increased risk of developing musculoskeletal injuries, a reduction in task speed and mobility, and overall performance degradation. However, these studies were limited to...article 2021
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Bourgonje, A.R. (author), Offringa, A.K. (author), van Eijk, L.E. (author), Abdulle, A.E. (author), Hillebrands, J.L. (author), van der Voort, P.H.J. (author), van Goor, H. (author), van Hezik, E.J. (author)Significance: Hydrogen sulfide (H2S) is one of the three main gasotransmitters that are endogenously produced in humans and are protective against oxidative stress. Recent findings from studies focusing on coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), shifted our attention to a...article 2021
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Munsters, C.C.B.M. (author), Kingma, B.R.M. (author), van den Broek, J. (author), Sloet van Oldruitenborgh-Oosterbaan, M.M. (author)In human sport science, the acute:chronic workload (ACWR) ratio is used to monitor an athlete's preparedness for competition and to assess injury risks. The aim of this study was to investigate whether acute and chronic workload calculations for external and internal loads (e.g. high-speed work distance and associated exertional effort) were...article 2020
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- Philippens, M.M.G.M.M. (author), Ouellet, S. (author) bookPart 2019
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Versluis, A. (author), van Os-Medendorp, H. (author), Blom, W.M. (author), Michelsen-Huisman, A.D. (author), Castenmiller, J.J.M. (author), Noteborn, H.P.J.M. (author), Houben, G.F. (author), Knulst, A.C. (author)Background: Cofactors, such as physical exercise and alcohol intake, might be associated with the severity or occurrence of food allergic reactions. Objective: To gain insight into the frequency of presence of potential cofactors in accidental food allergic reactions in adults and to what extent these factors influence the severity and...article 2019
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Bieler, D. (author), Cernak, I. (author), Martineau, L. (author), Bjarnason, S. (author), Franke, A. (author), Kirkman, E. (author), Leggieri, J. (author), Orru, H. (author), Ouellet, S. (author), Philippens, M.M.G.M. (author), Risling, M.G. (author), Sarron, J.C. (author), Skriudalen, S. (author), Teland, J.A. (author), Watts, S. (author), Gupta, R. (author)Blast injuries are often caused by more than one mechanism, do not occur in isolation, and typically elicit a secondary multi-system response. Research efforts often do not separate blast injuries caused by blast waves from those caused by blunt force trauma and other mechanisms. 15 experts from nine different NATO nations developed in the HFM...conference paper 2019
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Watts, S. (author), Kirkman, E. (author), Bieler, D. (author), Bjarnason, S. (author), Franke, A. (author), Gupta, R. (author), Leggieri, M.J. (author), Orru, H. (author), Ouellet, S. (author), Philippens, M.M.G.M. (author), Sarron, J.C. (author), Skriudalen, S. (author), Teland, J.A. (author), Risling, M. (author), Cernak, I. (author)Blast injury is a very complex phenomenon and frequently results in multiple injuries. One method to investigate the consequences of blast injuries is with the use of living systems (animal models). The use of animals allows the examination and evaluation of injury mechanisms in a more controlled manner, allowing variables such as primary or...conference paper 2019
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Kartaram, S. (author), Mensink, M. (author), Teunis, M. (author), Schoen, E. (author), Witte, G. (author), Janssen Duijghuijsen, L. (author), Verschuren, M. (author), Mohrmann, K. (author), M'Rabet, L. (author), Knipping, K. (author), Wittink, H. (author), van Helvoort, A. (author), Garssen, J. (author), Witkamp, R. (author), Pieters, R. (author), van Norren, K. (author)Background & aims: Plasma citrulline concentration is considered to be a marker for enterocyte metabolic mass and to reflect its reduction as may occur during intestinal dysfunction. Strenuous exercise can act as a stressor to induce small intestinal injury. Our previous studies suggest that this comprises the intestinal ability to produce...article 2019
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Tompa, E. (author), Mofidi, A. (author), van den Heuvel, S. (author), van Bree, T. (author), Michaelsen, F. (author), Jung, Y. (author), Porsch, L. (author), van Emmerik, M. (author)Insight into the financial consequences of work-related injuries and diseases provides governments, policy makers and employers’ organisations with relevant data for the purpose of developing OSH policies and agreements. Also, insight into these costs will help to raise awareness of the magnitude of the problem and will contribute to a more...other 2019
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Tompa, E. (author), Mofidi, A. (author), van den Heuvel, S. (author), van Bree, T. (author), Michaelsen, F. (author), Jung, Y. (author), Porsch, L. (author), van Emmerik, M. (author)The need to improve working life in the European Union (EU) is still urgent today. In 2016, approximately 2.4 million non-fatal accidents requiring at least 4 days of absence from work and 3,182 fatal accidents were reported in EU Member States. In addition to these accident rates, figures from 2013 show that 7.9 % of the workforce suffered from...report 2019
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- Michael, J. (author), Leggieri, Jr. (author), Bieler, D. (author), Bjarnason, S. (author), Cernak, I. (author), Franke, A. (author), Kirkman, E. (author), Martineau, L. (author), Orru, H. (author), Ouellet, S. (author), Philippens, M.M.G.M. (author), Risling, G. (author), Sarron, J.C. (author), Skriudalen, S. (author), Teland, J.A. (author), Watts, S. (author), Gupta, R.K. (author) conference paper 2018
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Brix, K.A. (author), Brody, D.L. (author), Grimes, J.B. (author), Yitzhak, A. (author), Agoston, D. (author), Aldag, M. (author), Armstrong, R. (author), Arun, P. (author), Audette, M. (author), Babcock, D. (author), Balaban, C. (author), Banton, R. (author), Bellgowan, P. (author), Borkholder, D. (author), Broglio, S. (author), Brokaw, E. (author), Cantu, R. (author), Carr, W. (author), Chapman, S. (author), Cmarik, J. (author), Colder, B. (author), Colombe, J. (author), Cook, D. (author), Cozzarelli, T. (author), Da Silva, U.O. (author), Daphalapurkar, N. (author), Dardzinski, B. (author), DeGraba, T. (author), DeMar, J. (author), DeWitt, D. (author), Dickstein, D. (author), Duckworth, J. (author), Elder, G. (author), Fazel-Rezai, R. (author), Fine, M. (author), Fiskum, G. (author), Fournier, A. (author), Ganpule, S. (author), Gill, J. (author), Glenn, J.F. (author), Greene, C. (author), Greig, N. (author), Haering, C. (author), Harrington, J. (author), Hein, A. (author), Helmick, K. (author), Hicks, R. (author), Hinds, S. (author), Hoffman, S. (author), Horkayne-Szakaly, I. (author), Iacono, D. (author), Ishii, E. (author), Jones, R.V. (author), Karami, G. (author), Krawczyk, D. (author), Labutta, R. (author), Latta, R. (author), Lattimore, T. (author), Leggieri, M. (author), Leonessa, F. (author), Lin, A. (author), Ling, G. (author), Long, M. (author), Lu, K.P. (author), Panker, S.M. (author), McCabe, J. (author), Merkle, A. (author), Montenigro, P. (author), Mueller, G.P. (author), Ng, L. (author), Nigam, S. (author), O'Donnell, J. (author), Okonkwo, D. (author), Pauli, I. (author), Perl, D. (author), Peskind, E. (author), Pfister, B. (author), Philippens, M. (author), Piehler, T. (author), Proctor, J. (author), Przekwas, A. (author), Qashu, F. (author), Raskind, M. (author), Razumovsky, A. (author), Reifman, J. (author), Reyes, P. (author), Rigby, P. (author), Risling, M. (author), Robinson, M. (author), Rooks, T. (author), Rosen, C. (author), Rosseau, G. (author), Sammons-Jackson, W. (author), Santago, A. (author), Shoge, R. (author), Sours, C. (author), Stone, J. (author), Templin, M. (author), Tepe, V. (author), Thielen, P. (author), Thomas, M. (author), Timmes, T. (author), Tortella, F. (author), Tucker, L. (author), Tweedie, D. (author), Hamm, D.V. (author), Christie Vu, B. (author), Wang, Y. (author), West, T. (author), Wilde, E. (author), Willis, A. (author), Wu, J. (author), Zai, L. (author), Zander, N. (author), Zheng, J. (author), Ziejewski, M. (author)The potential relationship between chronic traumatic encephalopathy (CTE) and head injuries such as blast-related traumatic brain injury (TBI) is an important area of study, particularly for military and contact sports populations, yet little is known about this relationship. To address this topic, the Department of Defense (DoD) Blast Injury...article 2017
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van den Heuvel, S. (author), van der Zwaan, L. (author), van Dam, L. (author), Oude Hengel, K.M. (author), Eekhout, I. (author), van Emmerik, M.L. (author), Oldenburg, C. (author), Brück, C. (author), Janowski, P. (author), Wilhelm, C. (author)This report presents the results of a survey of national and international data sources on the costs of work-related injuries, illnesses and deaths. The aim was to evaluate the quality and comparability of different sources as a first step towards estimating the costs of accidents and ill-health at work in Europe. The survey found that there...report 2017
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van der Voort, M.M. (author), Holm, K.B. (author), Kummer, P.O. (author), Teland, J.A. (author), van Doormaal, J.C.A.M. (author), Dijkers, H.P.A. (author)An important blast injury mechanism is the rupture of the lungs and the gastrointestinal tract. In explosives safety studies and threat analysis the empirical model of Bowen is often used to quantify this mechanism. The original model predicts the lethality for a person in front of a reflecting surface caused by simple Friedlander blast waves....article 2016
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Erbe, C. (author), Ainslie, M.A. (author), de Jong, C.A.F. (author), Racca, R. (author), Stocker, M. (author)As concern about anthropogenic noise and its impacts on marine fauna is increasing around the globe, data are being compared across populations, species, noise sources, geographic regions, and time. However, much of the raw and processed data are not comparable due to differences in measurement methodology, analysis and reporting, and a lack of...conference paper 2016
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de Jong, C.A.F. (author), Ainslie, M.A. (author), Heinis, F. (author), Janmaat, J. (author)The underwater sound produced during construction of the Port of Rotterdam harbor extension (Maasvlakte 2) was measured, with emphasis on the contribution of the trailing suction hopper dredgers during their various activities: dredging, transport, and discharge of sediment. Measured source levels of the dredgers, estimated source levels of...bookPart 2016
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Wijermars, L.G.M. (author), Schaapherder, A.F. (author), de Vries, D.K. (author), Verschuren, L. (author), Wüst, R.C.I. (author), Kostidis, S. (author), Mayboroda, O.A. (author), Prins, F. (author), Ringers, J. (author), Bierau, J. (author), Bakker, J.A. (author), Kooistra, T. (author), Lindeman, J.H.N. (author)Delayed graft function (DGF) following kidney transplantation affects long-term graft function and survival and is considered a manifestation of ischemia reperfusion injury. Preclinical studies characterize metabolic defects resulting from mitochondrial damage as primary driver of ischemia reperfusion injury. In a comprehensive approach that...article 2016