Searched for: subject%3A%22Infrapatellar%255C%2Bfat%255C%2Bpad%22
(1 - 3 of 3)
Kozijn, A.E. (author)
This thesis aimed to investigate how metabolic overload contributes to the pathophysiology of knee OA. We explored the role of these independent yet intertwined processes using state-of-the-art lipidomic and cellular approaches in mouse models of diet-induced OA. Chapter 2 presents an overview of twelve preclinical studies in which mice received...
doctoral thesis 2020
de Jong, A.J. (author), Klein-Wietinga, I.R. (author), Andersen, S.N. (author), Kwekkeboom, J.C. (author), Herb-van Toorn, L. (author), de Lange-Brokaar, B.J.E. (author), van Delft, D. (author), Garcia, J. (author), Wei, W. (author), van der Heide, H.J.L. (author), Bastiaanen-Jenniskens, Y.M. (author), van Osch, G.J.V.M. (author), Zuurmond, A.M. (author), Stojanovic-Susulic, V. (author), Nelissen, R.G. (author), Toes, R.E.M. (author), Kloppenburg, M. (author), Ioan-Facsinay, A. (author)
Background. Obesity is associated with the development and progression of osteoarthritis (OA). Although the infrapatellar fat pad (IFP) could be involved in this association, due to its intracapsular localization in the knee joint, there is currently little known about the effect of obesity on the IFP. Therefore, we investigated cellular and...
article 2017
Klein-Wieringa, I.R. (author), de Lange-Brokaar, B.J. (author), Yusuf, E. (author), Andersen, S.N. (author), Kwekkeboom, J.C. (author), Kroon, H.M. (author), van Osch, G.J. (author), Zuurmond, A.M. (author), Stojanovic-Susulic, V. (author), Nelissen, R.G. (author), Toes, R.E. (author), Kloppenburg, M. (author), Ioan-Facsinay, A. (author)
Objective: To get a better understanding of inflammatory pathways active in the osteoarthritic (OA) joint, we characterized and compared inflammatory cells in the synovium and the infrapatellar fat pad (IFP) of patients with knee OA. Methods: Infiltrating immune cells were characterized by flow cytometry in 76 patients with knee OA (mean age 63...
article 2016