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Koudstaal, W. (author), Hartgroves, L. (author), Havenga, M. (author), Legastelois, I. (author), Ophorst, C. (author), Siewerts, M. (author), Zuijdgeest, D. (author), Vogels, R. (author), Custers, J. (author), de Boer-Luijtze, E. (author), de Leeuw, O. (author), Cornelissen, L. (author), Goudsmit, J. (author), Barclay, W. (author), TNO Kwaliteit van Leven (author)
Reverse genetics, the generation of influenza viruses from cDNA, presents a rapid method for creating vaccine strains. The technique necessitates the use of cultured cells. Due to technical and regulatory requirements, the choice of cell lines for production of human influenza vaccines is limited. PER.C6® cells, among the most extensively...
article 2009
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Perenboom, R.J.M. (author), Davidse, W. (author), TNO Preventie en Gezondheid (author)
Background. To increase the coverage of influenza vaccination in groups of patients at risk, an experiment was conducted in 1993, aimed at logistic support of general practitioners (GPs). Methods. Support was given to 56 GPs with 133 000 patients to select and invite patients at risk. The coverage of vaccination as a result of this experiment...
article 1996