Searched for: subject%3A%22Human%255C%2Bexperiment%22
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Licht, C.M.M. (author), van Turenhout, L.C. (author), Deijen, J.B. (author), Koppes, L.L.J. (author), van Mechelen, W. (author), Twisk, J.W.R. (author), Drent, M.L. (author)
Several studies have demonstrated an association between polymorphisms in the insulin-like growth factor-1 (IGF-1) gene and IGF-1 serum levels. IGF-1 levels have been associated with cognitive functioning in older persons and growth hormone deficient patients. The present study investigates whether IGF-1 polymorphisms, IGF-1 levels, and...
article 2014
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Koopmans, L. (author), Bernaards, C.M. (author), Hildebrandt, V.H. (author), de Vet, H.C.W. (author), van der Beek, A.J. (author)
OBJECTIVE:: To examine the construct validity of the Individual Work Performance Questionnaire (IWPQ). METHODS:: A total of 1424 Dutch workers from three occupational sectors (blue, pink, and white collar) participated in the study. First, IWPQ scores were correlated with related constructs (convergent validity). Second, differences between...
article 2014
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Ellegast, R.P. (author), Kraft, K. (author), Groenesteijn, L. (author), Krause, F. (author), Berger, H. (author), Vink, P. (author)
Prolonged and static sitting postures provoke physical inactivity at VDU workplaces and are therefore discussed as risk factors for the musculoskeletal system. Manufacturers have designed specific dynamic office chairs featuring structural elements which promote dynamic sitting and therefore physical activity. The aim of the present study was to...
article 2012
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Coenen, P. (author), Kingma, I. (author), Boot, C.R.L. (author), Faber, G.S. (author), Xu, X. (author), Bongers, P.M. (author), van Dieën, J.H. (author)
This study aimed to develop, compare and validate two versions of a video analysis method for assessment of low back moments during occupational lifting tasks since for epidemiological studies and ergonomic practice relatively cheap and easily applicable methods to assess low back loads are needed. Ten healthy subjects participated in a protocol...
article 2011
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Mariani, B. (author), Hoskovec, C. (author), Rochat, S. (author), Büla, C. (author), Penders, J. (author), Aminian, K. (author), Laboratory of Movement Analysis and Measurements, Ecole Polytechnique Fédérale de Lausanne, -STI-IBI2-LMAM, Station 11/ELH 137, CH-1015 Lausanne, Switzerland Service of Geriatric Medicine, CHUV and CUTR Sylvana, Epalinges, Switzerland Holst Centre/IMEC, High Tech Campus 31, Eindhoven, Netherlands (author)
This study describes the validation of a new wearable system for assessment of 3D spatial parameters of gait. The new method is based on the detection of temporal parameters, coupled to optimized fusion and de-drifted integration of inertial signals. Composed of two wirelesses inertial modules attached on feet, the system provides stride length,...
article 2010
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Berger, M.A.M. (author), Krul, A. (author), Daanen, H.A.M. (author), TNO Defensie en Veiligheid (author)
Finger dexterity tests are generally used to assess performance decrease due to gloves, cold and pathology. It is generally assumed that the O’Connor and Purdue Pegboard test yield similar results. In this experiment we compared these two tests for dry conditions without gloves, and for dry and wet conditions with two types of Nytril gloves. In...
article 2009
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Mars, M. (author), Hogenkamp, P.S. (author), Gosses, A.M. (author), Stafleu, A. (author), de Graaf, C. (author), TNO Kwaliteit van Leven (author)
A higher viscosity of a food leads to a longer orosensory stimulation. This may facilitate the learned association between sensory signals and metabolic consequences. In the current study we investigated the effect of viscosity on learned satiation. In two intervention groups a low viscosity (LV) yogurt (n = 24) and a high viscosity (HV) yogurt ...
article 2009
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Vogel, I. (author), Verschuure, H. (author), van der Ploeg, C.P.B. (author), Brug, J. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. The goal was to assess risky and protective listening behaviors of adolescent users of MP3 players and the association of these behaviors with demographic characteristics and frequency of use. METHODS. In 2007, 1687 adolescents (12-19 years of age) in 68 classes in 15 Dutch secondary schools were invited to complete questionnaires...
article 2009
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Koelewijn, T. (author), Bronkhorst, A. (author), Theeuwes, J. (author), TNO Defensie en Veiligheid (author)
There is debate in the crossmodal cueing literature as to whether capture of visual attention by means of sound is a fully automatic process. Recent studies show that when visual attention is endogenously focused sound still captures attention. The current study investigated whether there is interaction between exogenous auditory and visual...
article 2009
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Graham, J.M.A. (author), Janssen, S.A. (author), Vos, H. (author), Miedema, H.M.E. (author), TNO Bouw en Ondergrond (author)
The relationships between road and rail traffic noise with pre-ejection period (PEP) and with respiratory sinus arrhythmia (RSA) during sleep, as indices of cardiac sympathetic and parasympathetic nervous system tone, were investigated in the field (36 subjects, with 188 and 192 valid subject nights for PEP and RSA, respectively). Two analyses...
article 2009
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Mert, A. (author), Klöpping-Ketelaars, I. (author), Bles, W. (author), TNO Defensie en Veiligheid (author)
Motion sickness incidence (MSI) for vertical sinusoidal motion reaches a maximum at 0.167 Hz. Normal breathing frequency is close to this frequency. There is some evidence for synchronization of breathing with this stimulus frequency. If this enforced breathing takes place over a larger frequency range (0.05-0.8 Hz) and whether this contributes...
article 2009
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Kersten, S. (author), Lichtenstein, L. (author), Steenbergen, E. (author), Mudde, K. (author), Hendriks, H.F.J. (author), Hesselink, M.K. (author), Schrauwen, P. (author), Müller, M. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE-: Plasma lipoprotein levels are determined by the balance between lipoprotein production and clearance. Recently, angiopoietin-like protein 4 (ANGPTL4) was uncovered as a novel endocrine factor that potently raises plasma triglyceride levels by inhibiting triglyceride clearance. However, very little is known about ANGPTL4 in human....
article 2009
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TNO Kwaliteit van Leven (author), Klaassens, E.S. (author), Boesten, R.J. (author), Haarman, M. (author), Knol, J. (author), Schuren, F.H. (author), Vaughan, E.E. (author), Vos, W.M.de (author)
Although their exact function remains enigmatic, bifidobacteria are among the first colonizers of the newborn infant gut and further develop into abundant communities, notably in response to diet. Therefore, the transcriptional responses of bifidobacteria in rapidly processed fecal samples from young infants that were fed either breast milk or a...
article 2009
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de Korte, E.M. (author), de Kraker, H. (author), Bongers, P.M. (author), van Lingen, P. (author), TNO Kwaliteit van Leven (author)
To study the effects of a tactile feedback signal in a computer mouse on reduction of hovering behaviour and consequently on changes in muscle load, productivity, comfort and user friendliness, a comparative, experimental study with repeated measures was conducted. Fifteen subjects performed five trials with different mouse actions and a...
article 2008
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Toet, A. (author), Jansen, S.E.M. (author), Delleman, N.J. (author), TNO Defensie en Veiligheid (author), Nato (author)
Field-of-view (FOV) restrictions are known to affect human behaviour and to degrade performance for a range of different tasks. However, the relationship between human locomotion performance in complex environments and FOV size is currently not fully known. This paper examined the effects of FOV restrictions on the performance of participants...
article 2008
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Berbée, J.F.P. (author), Mooijaart, S.P. (author), de Craen, A.J.M. (author), Havekes, L.M. (author), van Heemst, D. (author), Rensen, P.C.N. (author), Westendorp, R.G.J. (author), TNO Kwaliteit van Leven (author)
The high-density lipoprotein (HDL) constituent apolipoprotein CI (apoCI) protects mice against mortality in bacterial sepsis. We assessed whether high plasma apoCI levels protect against mortality from infection in humans. We determined plasma levels of apoCI, lipids, and C-reactive protein in 85-year-old participants of the prospective...
article 2008
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Faber, G.S. (author), Kingma, I. (author), Delleman, N. (author), van Dieën, J. (author)
This study investigated the effects of ship motion on peak spinal loading during lifting. All measurements were done on a ship at sea. In 1-min trials, which were repeated over a wide range of sailing conditions, subjects lifted an 18 kg box five times. Ship motion, whole body kinematics, ground reaction forces and electromyography were measured...
article 2008
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de Kraker, H. (author), de Korte, E. (author), van Mil, F. (author), Rijs, B. (author), Bongers, P. (author), TNO Kwaliteit van Leven (author)
The aim of this study was to determine the effect of a tactile feedback signal on hovering behaviour, productivity, usability and comfort after 1 week of using an experimental mouse. In a randomized controlled trial, a regular computer mouse was compared to a new developed mouse with a tactile, vibrating feedback signal to prevent unnecessary...
article 2008
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Beelen, R. (author), Hoek, G. (author), van den Brandt, P.A. (author), Goldbohm, R.A. (author), Fischer, P. (author), Schouten, L.J. (author), Armstrong, B. (author), Brunekreef, B. (author), TNO Kwaliteit van Leven (author)
Background: Most studies on the association between lung cancer and air pollution have investigated mortality. There have been few studies of lung cancer incidence. Methods: We used data from the ongoing Netherlands Cohort Study on Diet and Cancer for 114,378 subjects with follow-up from September 1986 to December 1997. Exposure to black smoke,...
article 2008
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de Wijk, R.A. (author), Zijlstra, N. (author), Mars, M. (author), de Graaf, C. (author), Prinz, J.F. (author), TNO Kwaliteit van Leven (author)
Two studies investigated the effect of a food's viscosity on bite size, bite effort and food intake using a standardized protocol in which subjects sipped through a straw every 20 s for a period of 15 min from one of two products, a chocolate-flavored dairy drink and a chocolate-flavored dairy semi-solid, matched for energy density. In the first...
article 2008
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