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van Zoelen, E.M. (author), van den Bosch, K. (author), Abbink, D. (author), Neerincx, M.A. (author)When humans and AI-agents collaborate, they need to continuously learn about each other and the task. We propose a Team Design Pattern that utilizes adaptivity in the behavior of human and agent team partners, causing new Collaboration Patterns to emerge. Human-AI Co-Learning takes place when partners can formalize recognized patterns of...conference paper 2023
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Krause, F. (author), Bosch, T. (author), Wilschut, E. (author), van Rhijn, G. (author)Technology aimed at providing cognitive support to operators in the manufacturing industry, is developing rapidly. Through technologies such as near-eye displays and augmented and mixed reality, the operator receives digital information and instructions to help the operator learn, and work efficiently and accurately. Companies, especially SMEs,...bookPart 2023
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de Vries, H.J. (author), Pennings, H.J.M. (author), van der Schans, C.P. (author), Sanderman, R. (author), Oldenhuis, H.K.E. (author), Kamphuis, W. (author)The effects of stress may be alleviated when its impact or a decreased stress-resilience are detected early. This study explores whether wearable-measured sleep and resting HRV in police officers can be predicted by stress-related Ecological Momentary Assessment (EMA) measures in preceding days and predict stress-related EMA outcomes in...article 2023
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Weening-Verbree, L.F. (author), Schuller, A.A. (author), Zuidema, S.U. (author), Hobbelen, J.S.M. (author)An Oral Care Program (OCP) was implemented in home care nursing teams in a northern province of the Netherlands to improve the oral health and hygiene of older people who make use of formal home care in 2018-2019. The aim of the current study was to evaluate the experiences of the stakeholders involved (older people, home-care nurses and dental...article 2023
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Mehrabani, B.B. (author), Erdmann, J. (author), Sgambi, L. (author), Snelder, M. (author)One of the potential capabilities of Connected and Autonomous Vehicles (CAVs) is that they can have different route choice behavior and driving behavior compared with human Driven Vehicles (HDVs). This will lead to mixed traffic flow with multiple classes of route choice behavior. Therefore, it is crucial to solve the multiclass Traffic...conference paper 2023
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Fransman, W. (author), Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author)Objectives: Within the chemical legislation, REACH was implemented in order to improve safe working conditions with hazardous substances. Literature and real-life experiences by those concerned have shown that there are still gaps with a need for improved risk communication. This study elaborated on how information provided by REACH is...article 2023
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Solms, L. (author), van Vianen, A.E.M. (author), Koen, J. (author), Kan, K.J. (author), de Hoog, M. (author), de Pagter, A.P.J. (author)BACKGROUND: Physicians increasingly show symptoms of burnout due to the high job demands they face, posing a risk for the quality and safety of care. Job and personal resources as well as support interventions may function as protective factors when demands are high, specifically in times of crisis such as the COVID-19 pandemic. Based on the Job...article 2023
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Fluitman, K.S. (author), Wijdeveld, M. (author), Davids, M. (author), van Ruiten, C.C. (author), Reinders, I. (author), Wijnhoven, H.A.H. (author), Keijser, B.J.F. (author), Visser, M. (author), Nieuwdorp, M. (author), IJzerman, R.G. (author)Expert groups argue to raise the recommended daily allowance for protein in older adults from 0.8 to 1.2 g/kg/day to prevent undernutrition. However, protein is thought to increase satiety, possibly through effects on gut microbiota and central appetite regulation. If true, raising daily protein intake may work counterproductively. In a...article 2023
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van Dommelen, P. (author), Barios, R.M. (author), Arnaud, L. (author), le Masne, Q. (author), Koledova, E. (author)Worldwide regulations during COVID-19 positively and negatively impacted self-management in paediatric patients with chronic medical conditions. We investigated the impact of regulations on adherence to recombinant human growth hormone (r-hGH) therapy in paediatric patients with growth disorders, using real-world adherence data extracted March...article 2023
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Santonen, T. (author), Mahiout, S. (author), Alvito, P. (author), Apel, P. (author), Bessems, J. (author), Bil, W. (author), Borges, T. (author), Bose-O'Reilly, S. (author), Buekers, J. (author), Canas Portilla, A.I. (author), Calvo, A.C. (author), de Alba González, M. (author), Dominguez-Morueco, N. (author), Lopez, M.E. (author), Falnoga, I. (author), Gerofke, A. (author), Caballero, M.D.C.G. (author), Horvat, M. (author), Huuskonen, P. (author), Kadikis, N. (author), Kolossa-Gehring, M. (author), Lange, R. (author), Louro, H. (author), Martins, C. (author), Meslin, M. (author), Niemann, L. (author), Diaz, S.P. (author), Plichta, V. (author), Porras, S.P. (author), Rousselle, C. (author), Scholten, B. (author), Silva, M.J. (author), Šlejkovec, Z. (author), Tratnik, J.S. (author), Joksic, A.Š. (author), Tarazona, J.V. (author), Uhl, M. (author), van Nieuwenhuyse, A. (author), Viegas, S. (author), Vinggaard, A.M. (author), Woutersen, M. (author), Schoeters, G. (author)One of the aims of the European Human Biomonitoring Initiative, HBM4EU, was to provide examples of and good practices for the effective use of human biomonitoring (HBM) data in human health risk assessment (RA). The need for such information is pressing, as previous research has indicated that regulatory risk assessors generally lack knowledge...article 2023
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Bhattacharya, C. (author), Sandinge, A.S. (author), Bragg, R.A. (author), Heijer, M. (author), Yan, J. (author), Andersson, L.C. (author), Jurva, U. (author), Pelay-Gimeno, M. (author), Vaes, W.H.J. (author), de Ligt, R.A.F. (author), Gränfors, M. (author), Amilon, C. (author), Lindstedt, E.L. (author), Menakuru, S.R. (author), Garkaviy, P. (author), Weidolf, L. (author), Gopaul, V.S. (author)This study evaluated the mass balance and disposition of AZD4831, a novel myeloperoxidase inhibitor, in six healthy participants using a 14C-labeled microtracer coupled with analysis by accelerator mass spectrometry (AMS). A single oral dose of 10 mg 14C-AZD4831 (14.8 kBq) was administered as a solution, and 14C levels were quantified by AMS in...article 2023
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Vreeken, D. (author), Seidel, F. (author), de La Roij, G. (author), Vening, W. (author), den Hengst, W.A. (author), Verschuren, L. (author), Özsezen, S. (author), Kessels, R.P.C. (author), Duering, M. (author), Mutsaerts, H.J.M.M. (author), Kleemann, R. (author), Wiesmann, M. (author), Hazebroek, E.J. (author), Kiliaan, A.J. (author)BACKGROUND AND OBJECTIVE: While underlying pathophysiology linking obesity to brain health is not completely understood, white adipose tissue (WAT) is considered a key player. In obesity, WAT becomes dysregulated, showing hyperplasia, hypertrophy, and eventually inflammation. This disbalance leads to dysregulated secretion of adipokines...article 2023
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Steijn, W.M.P. (author), van Gulijk, C. (author), van der Beek, D. (author), Sluijs, T. (author)Cooperative robots in the workspace have an effect on safety that is not yet fully understood. This work collates pre-existing knowledge on human, technological and organizational factors for human-robot interaction and develops a system dynamics model that captures the complex interactions. Expert consultation in the form of a Delphi study is...article 2023
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van Diggelen, J. (author), Metcalfe, J.S. (author), van den Bosch, K. (author), Neerincx, M. (author), Kerstholt, J. (author)Following the rapid rise of military Artificial Intelligence (AI), people have warned against mankind withdrawing from the immediate war-related events resulting in the “dehumanization” of war (Joerden, 2018). The premise that machines decide what is destroyed and what is spared, and when to take a human life, would be deeply morally...article 2023
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van Kampen, J. (author), Lammers, M. (author), Steijn, W. (author), Guldenmund, F. (author), Groeneweg, J. (author)In the Netherlands, approximately 2.300 workers have a serious reportable accident at work every year, of which around 60 are fatal (Inspectie SZW, 2020; Bellamy et al., 2014). Safety practitioners employ many methods to improve occupational safety for workers within their companies. Interventions might, for example, be aimed at improving...article 2023
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Cavallera, V. (author), Lancaster, G. (author), Gladstone, M. (author), Black, M.M. (author), McCray, G. (author), Nizar, A. (author), Ahmed, S. (author), Dutta, A. (author), Anago, R.K.E. (author), Brentani, A. (author), Jiang, F. (author), Schönbeck, Y. (author), McCoy, D.C. (author), Kariger, P. (author), Weber, A.M. (author), Raikes, A. (author), Waldman, M. (author), van Buuren, S. (author), Kaur, R. (author), Pérez Maillard, M. (author), Nisar, M.I. (author), Khanam, R. (author), Sazawal, S. (author), Zongo, A. (author), Pacifico Mercadante, M. (author), Zhang, Y. (author), Roy, A.D. (author), Hepworth, K. (author), Fink, G. (author), Rubio-Codina, M. (author), Tofail, F. (author), Eekhout, I. (author), Seiden, J. (author), Norton, R. (author), Baqui, A.H. (author), Ali, J.K. (author), Zhao, J. (author), Holzinger, A. (author), Detmar, S. (author), Kembou, S.N. (author), Begum, F. (author), Ali, S.M. (author), Jehan, F. (author), Dua, T. (author), Janus, M. (author)Introduction Children's early development is affected by caregiving experiences, with lifelong health and well-being implications. Governments and civil societies need population-based measures to monitor children's early development and ensure that children receive the care needed to thrive. To this end, the WHO developed the Global Scales for...article 2023
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Albers, N. (author), Neerincx, M.A. (author), Aretz, N.L. (author), Ali, M. (author), Ekinci, A. (author), Brinkman, W.P. (author)Virtual coaches have the potential to address the low adherence common to eHealth applications for behavior change by, for example, providing motivational support. However, given the multitude of factors affecting users’ attitudes toward virtual coaches, more insights are needed on how such virtual coaches can be designed to affect these...conference paper 2023
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de Hoogh, I.M. (author), Reinders, M.J. (author), Doets, E.L. (author), Hoevenaars, F.P.M. (author), Top, J.L. (author)The current health status of the general public can substantially benefit from a healthy diet. Using a personalized approach to initiate healthy dietary behavior seems to be a promising strategy, as individuals differ in terms of health status, subsequent dietary needs, and their desired behavior change support. However, providing personalized...article 2023
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Vreeken, D. (author), Seidel, F. (author), Custers, E.M. (author), Olsthoorn, L. (author), Cools, S. (author), Aarts, E.O. (author), Kleemann, R. (author), Kessels, R. (author), Weismann, M. (author), Hazebroek, E.J. (author), Killiaan, A.J. (author)Importance: Bariatric surgery-induced weight loss is often associated with improved cognitive function. However, improvement in cognitive function is not always exhibited by all patients, and the mechanisms behind cognitive improvement remain unknown. Objective: To investigate the association of changes in adipokines, inflammatory factors, mood,...article 2023
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Stevens, L.J. (author), Dubbeld, J. (author), Doppenberg, J.B. (author), van Hoek, B. (author), Menke, A.L. (author), Donkers, J.M. (author), Alsharaa, A. (author), de Vries, A. (author), Vaes, W.H.J. (author), Knibbe, C.A.J. (author), van de Steeg, E. (author), Alwayn, I.P.J. (author)Realistic models predicting hepatobiliary processes in health and disease are lacking. We therefore aimed to develop a physiologically relevant human liver model consisting of normothermic machine perfusion (NMP) of explanted diseased human livers that can assess hepatic extraction, clearance, biliary excretion, and drug-drug interaction (DDI)....article 2023