Endothelial function and baroreflex sensitivity according to the oral glucose tolerance test in patients with coronary artery disease and normal fasting glucose levels

Endothelial dysfunction and reduced BRS (baroreflex sensitivity) may be present in patients with CAD (coronary artery disease). The normal fasting glucose level does not exclude abnormal glucose metabolism in patients with CAD. The aim of present study was to evaluate endothelial function and BRS according to glucose metabolism in patients with...

Randvoorwaarden aan een verblijf op grote hoogte bij bestaande gezondheidsproblemen [Preconditions for a stay in high altitude areas in the case of existing health problems]

Various symptoms can arise during a stay in high altitude areas (above 2500 m), such as tissue hypoxia and in particular pulmonary and brain oedema. Patients with existing health problems can expect to develop more complaints or more severe complaints at an earlier stage. For a number of these patients a stay in high altitude areas should be...

Thoracic sympathectomy: Effects on hemodynamics and baroreflex control

Endoscopic thoracic sympathectomy at T2-T4 is an effective and safe treatment for primary axillary and palmar hyperhidrosis and facial blushing refractory to conventional treatment. T2 and T4 ganglia however are in the direct pathway of sympathetic innervation of the heart and part of the vasomotor nerves. In this study we investigate possible...

Continuous stroke volume monitoring by modelling flow from non-invasive measurement of arterial pressure in humans under orthostatic stress

The relationship between aortic flow and pressure is described by a three-element model of the arterial input impedance, including continuous correction for variations in the diameter and the compliance of the aorta (Modelflow). We computed the aortic flow from arterial pressure by this model, and evaluated whether, under orthostatic stress,...

Variability of near-fainting responses in healthy 6-16-year-old subjects

1. Fainting is a common phenomenon in young subjects, but the final events before the actual faint are not well known. The aim of the present study was to study the inter-individual variability of haemodynamic events associated with near-fainting in children and teenagers. 2. Sixty-eight healthy subjects (aged 6-16 years) performed a 70°tilt-up...

Diabetic angiopathy: Tracking down the culprits