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Fransman, W. (author), Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author)Objectives: Within the chemical legislation, REACH was implemented in order to improve safe working conditions with hazardous substances. Literature and real-life experiences by those concerned have shown that there are still gaps with a need for improved risk communication. This study elaborated on how information provided by REACH is...article 2023
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Theunissen, M.H.C. (author), de Wilde, J.A. (author), Bezem, J. (author), van Harten, L. (author)Introduction. A uniform triage protocol is developed for Preventive Child Healthcare (PCH) to improve the quality of detection of health problems in primary school children by PCH. The aim of this study is to investigate 1) the psychometric properties and 2) satisfaction of PCH professionals of this uniform triage protocol. Methods. We included...article 2022
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Sewell, F. (author), Strupp, C. (author), van der Laan, J.W. (author), Wolf, D.C. (author), Wolterink, G. (author), Woutersen, R. (author), Zvonar, Z. (author), Heusinkveld, H. (author), Braakhuis, H. (author)Currently the only methods for non-genotoxic carcinogenic hazard assessment accepted by most regulatory authorities are lifetime carcinogenicity studies. However, these involve the use of large numbers of animals and the relevance of their predictive power and results has been scientifically challenged. With increased availability of innovative...article 2020
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Pizzol, L. (author), Hristozov, D. (author), Zabeo, A. (author), Gianpietro, B. (author), Wohlleben, W. (author), Koivisto, A.J. (author), Jensen, K.A. (author), Fransman, W. (author), Stone, V. (author), Marcomini, A. (author)The increasing use of engineered nanomaterials (ENMs) in nano-enabled products (NEPs) has raised societal concerns about their possible health and ecological implications. To ensure a high level of human and environmental protection it is essential to properly estimate the risks of these new materials and to develop adequate risk management...article 2019
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- Douwes, M. (author), Könemann, R. (author), Hoozemans, M. (author), Kuijer, P. (author), Vermeulen, H. (author) conference paper 2019
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Koivisto, A.J. (author), Pizzol, L. (author), Basei, G. (author), Zabeo, A. (author), Mackevica, A. (author), Hansen, S.F. (author), Gosens, I. (author), Cassess, F.R. (author), de Jong, W. (author), Koivisto, A.J. (author), Neubauer, N. (author), Sanchaz, J.A. (author), Semenzin, E. (author), Subramanian, V. (author), Fransman, W. (author), Jensen, K.A. (author), Wohlleben, W. (author), Stone, V. (author), Marcomini, A. (author)The use of nano-scale copper oxide (CuO) and basic copper carbonate (Cu2(OH)2CO3) in both ionic and micronized wood preservatives has raised concerns about the potential of these substances to cause adverse humans health effects. To address these concerns, we performed quantitative (probabilistic) human health risk assessment (HHRA) along the...article 2018
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Deziel, N.C. (author), Nuckols, J.R. (author), Jones, R.R. (author), Graubard, B.I. (author), de Roos, A.J. (author), Pronk, A. (author), Gourley, C. (author), Colt, J.S. (author), Ward, M.H. (author)Proximity to facilities emitting polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/F) has been associated with increased risk of non-Hodgkin lymphoma (NHL). There is limited information about whether proximity to industrial sources leads to indoor PCDD/F contamination of homes. We measured carpet dust concentrations (pg/g...article 2017
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Cohen, I. (author), den Braber, N. (author), Smets, N.J.J.M. (author), van Diggelen, J. (author), Brinkman, W.P. (author), Neerincx, M.A. (author)In high-risk domains such as human space flight, cognitive performances can be negatively affected by emotional responses to events and conditions in their working environment (e.g., isolation and health incidents). The COgnitive Performance and Error (COPE) model distinguishes effects of work content on cognitive task load and emotional state,...article 2016
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Binsch, O. (author), Wabeke, T.R. (author), Valk, P.J.L. (author)Leveraging miniaturized sensor and monitoring technology integrated in easy-to-wear wristband wearables represents a great opportunity for advancing Resilience and Mental Health of e.g. employees that experience high workload. Therefore, it is important to gain insights into the reliability of such technology before far reaching conclusions can...conference paper 2016
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Barlow, S.M. (author), Boobis, A.R. (author), Bridges, J. (author), Cockburn, A. (author), Dekant, W. (author), Hepburn, P. (author), Houben, G.F. (author), König, J. (author), Nauta, M.J. (author), Schuermans, J. (author), Bánáti, D. (author)Background: Food legislation in the European Union and elsewhere includes both hazard- and risk-based approaches for ensuring safety. In hazard-based approaches, simply the presence of a potentially harmful agent at a detectable level in food is used as a basis for legislation and/or risk management action. Risk-based approaches allow...article 2015
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Remoundou, K. (author), Brennan, M. (author), Sacchettini, G. (author), Panzone, L. (author), Butler-Ellis, M.C. (author), Capri, E. (author), Charistou, A. (author), Chaideftou, E. (author), Gerritsen-Ebben, M.G. (author), Machera, K. (author), Spanoghe, P. (author), Glass, R. (author), Marchis, A. (author), Doanngoc, K. (author), Hart, A. (author), Frewer, L.J. (author)The EU Directive on the sustainable use of pesticides (EU128/2009/EC) requires European Member States to develop training activities targeting occupational exposure to pesticides, and communication material aimed at residents and bystanders. Risk perceptions, knowledge and attitudes associated with passive and occupational exposure to pesticide...article 2015
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Hayes, D.J. (author), van Buuren, S. (author), ter Kuile, F.O. (author), Stasinopoulos, D.M. (author), Rigby, R.A. (author), Terlouw, D.J. (author)Methods: A weight-for-age database was constructed from pre-existing population-based anthropometric data obtained from household surveys and research groups. It contained data collected between 1995 and 2012 on 1 263 119 individuals (909 368 female, 353 751 male) older than 14 days and younger than 50 years in 64 malaria-endemic countries....article 2015
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Hiemstra-van Mastrigt, S. (author), Kamp, I. (author), van Veen, S.A.T. (author), Vink, P. (author), Bosch, T. (author)New technologies have led to an increasingly sedentary lifestyle. Sedentary behaviour is characterised by physical inactivity and is associated with several health risks. This excessive sitting does not only take place in the office or at home, but also during daily commute. Therefore, BMW AG developed an active seating system for the back seat...article 2015
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Offermans, N.S.M. (author), Vermeulen, R. (author), Burdorf, A. (author), Goldbohm, R.A. (author), Keszei, A.P. (author), Peters, S. (author), Kauppinen, T. (author), Kromhout, H. (author), van den Brandt, P.A. (author)Objectives The evidence for an association between occupational asbestos exposure and pharyngeal cancer (PhC) is limited, while for oral cavity cancer (OCC) the literature is even sparser. We studied OCC and PhC risk both separately and combined (OCPC) in relation to occupational asbestos exposure, specifically addressing the influence of...article 2014
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Kalkman, I.M. (author), Lentzen, S.S.K. (author), Courage, W.M.G. (author), Napoles, O.M. (author), Galanti, F.M.B. (author)In general the condition of a structure can be assessed in terms of a performance indicator. For example, this can be the strength of a structure. An asset manager is concerned with ensuring that the performance of a structure does not fall below a given minimum level. This can be achieved by inspecting or monitoring the structure. As the...conference paper 2011
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Beurskens-Comuth, P.A.W.V. (author), Verbist, K. (author), Brouwer, D. (author), TNO Kwaliteit van Leven (author)Objectives: There is a growing awareness of the potential risks for human health of exposure to ultrafine particles or nanoparticles. In that context, workplace air measurements become important, and various strategies have been developed to monitor exposure. In addition, observations and time/activity registrations are part of the exposure...article 2011
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Taris, T.W. (author), Ybema, J.F. (author), Beckers, D.G.J. (author), Verheijden, M.W. (author), Geurts, S.A. (author), Kompier, M.A.J. (author)BACKGROUND: It has often been suggested that high levels of overtime lead to adverse health outcomes. One mechanism that may account for this association is that working overtime leads to elevated levels of stress, which could affect worker's behavioral decisions or habits (such as smoking and lack of physical activity). In turn, this could lead...article 2011
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Savolainen, K. (author), Pylkkänen, L. (author), Norppa, H. (author), Falck, G. (author), Lindberg, H. (author), Tuomi, T. (author), Vippola, M. (author), Alenius, H. (author), Hämeri, K. (author), Koivisto, J. (author), Brouwer, D. (author), Mark, D. (author), Bard, D. (author), Berges, M. (author), Jankowska, E. (author), Posniak, M. (author), Farmer, P. (author), Singh, R. (author), Krombach, F. (author), Bihari, P. (author), Kasper, G. (author), Seipenbusch, M. (author), TNO Kwaliteit van Leven (author)The significance of engineered nanomaterials (ENM) and nanotechnologies grows rapidly. Nanotechnology applications may have a positive marked impact on many aspects of on human every day life, for example by providing means for the production of clean energy and pure drinking water. Hundreds of consumer nano-based products are already on the...article 2010
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Kardinaal, A. (author), Mennen, L. (author), Hendriks, H. (author), TNO Kwaliteit van Leven (author)Alwine Kardinnal, Louise Mennen, and Henk Hendriks share their views on the way scientific evidence for a health claim can be obtained and use weight management to demonstrate different approaches. Weight management products are used to explain the steps that need to be taken to obtain approval for health claims and the way to gather scientific...article 2009
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Poot, A. (author), Quik, J.T.K. (author), Veld, H. (author), Koelmans, A.A. (author), TNO Bouw en Ondergrond (author)Black Carbon (BC) quantification methods are reviewed, including new Rock-Eval 6 data on BC reference materials. BC has been reported to have major impacts on climate, human health and environmental quality. Especially for risk assessment of persistent organic pollutants (POPs) it is important to account for risk reduction caused by BC, as...article 2009