Polyethylene terephthalate bottles (PRBs): A health and safety assessment

As part of a multi-client project, the potential public health risks of the reuse of polyethylene terephthalate (PET) refillable bottles (PRBs) following possible misuse has been investigated. Participants in the project provided data and information from previous studies conducted independently at contract laboratories. These studies were...

Photoreceptor light adaptation models: an evaluation

Two current descriptions of photoreceptor responses in the presense of adapting background illumination are evaluated. Both descriptions are based on the Michaelis-Menten equation V/V(m) = I(n)/(I(n) + ??(n)), but they use this equation in different ways: (1) to describe increment responses to light increments on a background (the 'increment ...

Adequate mothering by partially isolated rhesus monkeys after observation of maternal care

13 laboratory-born female monkeys were allowed to remain with their mothers for about 4 mo and were subsequently singly caged in rooms where they were able to see other monkeys. Ss that did not see mothers caring for their infants neglected their own firstborn. In contrast, Ss that were allowed to observe separately caged mother–infant pairs...

Transient tritanopia at the level of the ERG b-wave

A blue stimulus that is just visible in the presence of a yellow adapting field remains invisible for several seconds after the yellow field has been turned off. This 'transient tritanopia' is shown to exist already at the level of the b-wave of the electroretinogram. The experiments were done on rhesus monkeys and the results were qualitatively...

Structural identity of the pluripotential hemopoietic stem cell

A review is presented of the experiments that resulted in the identification of a specific morphologic entity representing the pluripotential hemopoietic stem cell (HSC) in mouse bone marrow. This entity was subsequently discovered in concentrated HSC preparations from bone marrow of rats, monkeys, and humans. In the mouse, a set of physical...

Haemodynamic changes in the cerebral circulation of the cat during occlusion of the middle cerebral artery

In a group of 21 cats, the middle cerebral artery pressure (MCAP) was recorded by means of a catheter introduced into the artery at its origin, just distal to the occlusion. The effects of hypertension, hypercapnia, and hypocapnia were studied. In a group of five cats, both middle cerebral arteries (MCA) were catheterized and the pressure was...

Inhibition of MLC responder and stimulator function with allo-antisera in rhesus monkeys

Ten antisera containing antibodies directed against specificities controlled by the Ia1 locus of rhesus monkeys were tested for their ability to inhibit the MLC reaction. In cultures with responding cells from the serum producer, all sera with anti-Ia1, activity depressed the stimulatory capacity of cells carrying the Ia1 antigen in question. In...

Effects of alkali treated proteins: Feeding studies with free and protein bound lysinoalanine in rats and other animals

To find out whether alkali treated proteins possess nephrotoxic properties, feeding studies were conducted with drastically treated soybean protein and casein, and also with lysinoalanine (LAL), the amino acid known to be formed in proteins subjected to high pH at an elevated temperature. The feeding of synthesized LAL to rats at dietary levels...

Identification of cells in primate bone marrow resembling the hemopoietic stem cell in the mouse

The colony forming unit culture (CFU C) in the thin layer agar colony technique is considered to be representative for hemopoietic stem cells (HSC), according to studies in mouse and monkey bone marrow. Using this in vitro assay as a guide, stem cell concentrates were prepared from monkey and human bone marrow by repeated density gradient...

Transplantation antigens in rhesus monkeys

Chemicals/CAS: Antigens