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TNO Preventie en Gezondheid (author), Amelink-Verburg, M.P. (author), van Roosmalen, J. (author), Roelofsen, J.M.T. (author), van den Wolleswinkel-Bosch, J.H. (author), Verloove-Vanhorick, S.P. (author)Objective. To evaluate a perinatal audit procedure by communicating the results to the caregivers (midwives and obstetricians) involved, in order to determine whether the audit led to specific suggestions for improving practice and whether evaluation of the panel assessments by caregivers leads to a different evaluation of the audit process....article 2003
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Tielemans, E. (author), Marquart, H. (author), de Cock, J. (author), Groenewold, M. (author), van Hemmen, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)There is a growing need for transparency concerning ways in which existing exposure data are weighted for their relative value and quality. Currently, this evaluation is largely subjective and is dependent on the quality of the judgement of the individual assessor or expert group. In this paper some general guidelines are presented for a quality...article 2002
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- van Hijum, S.A.F.T. (author), van Geel-Schutten, G.H. (author), Rahaoui, H. (author), van der Maarel, M.J.E.C. (author), Dijkhuizen, L. (author), TNO Voeding (author) article 2002
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TNO Voeding (author), Tielemans, E. (author), Christopher, Y. (author), Marquart, H. (author), Groenewold, M. (author), van Hemmen, J. (author)In a recent issue of this journal, Money and Margary (2002) proposed some thoughtful guidelines for exposure assessment in regulatory risk assessment. Their structured approach acknowledges that currently available exposure data are of very variable quality (Northage and Marquart, 2001). We firmly underline their plea for a hierarchy in...article 2002
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Hulshof, K.F.A.M. (author), Valsta, L.M. (author), Welten, D.C. (author), Löwik, M.R.H. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Objective: To show the effects of statistical approaches of data analysis to be used in the development of Food-Based Dietary Guidelines (FBDG). Setting: Databases from dietary surveys in 6 European countries. Results: Quantile analysis based on iron intake among adult women resulted in differences among European countries regarding (macro)...article 2001
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Hakkert, B.C. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The regulatory requirements for the registration of pesticides are mainly evolved from concern about dietary exposure and risk, i.e. chronic oral exposure. Pesticide workers, however, are predominantly exposed dermally and intermittently. The present critique provides suggestions for improvement of toxicity studies to refine the risk assessment...article 2001
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Schipper, H.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Chemicals/CAS: Pesticidesarticle 2001
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Energieonderzoek Centrum Nederland (author), Martens, J.W. (author), Kaufman, S. (author), Green, J. (author)N.V.T.report 2001
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van Wouwe, J.P. (author), Siderius, E.J. (author), Borstlap, R. (author), Nijenhuis, Th.A. (author), Hirasing, R.A. (author)Children with Down's syndrome have an increased risk of congenital anomalies and additional medical problems. These can be treated but are often seen as part of the syndrome and not as the cause of developmental retardation. Based on the current level of knowledge, specific medical tests and evaluations are recommended. The reasons for these...article 2001
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Sartorelli, P. (author), Andersen, H.R. (author), Angerer, J. (author), Corish, J. (author), Drexler, H. (author), Göen, T. (author), Griffin, P. (author), Hotchkiss, S.A.M. (author), Larese, F. (author), Montomoli, L. (author), Perkins, J. (author), Schmelz, M. (author), van de Sandt, J. (author), Williams, F. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)During the last few years the general interest in the percutaneous absorption of chemicals has increased. It is generally accepted that there is very few reliable quantitative and qualitative data on dermal exposure to chemicals in the general population and in occupationally exposed workers. In order to predict the systemic risk of dermally...article 2000
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van Herten, L.M. (author), Gunning-Schepers, L.J. (author)This article reviews the start of the use of targets as a tool in health policy, summarises the fruitful uses and frequently-heard objections, and proposes some conditions for successful health target setting. Targets as tool in health policy are based on the 'management by objectives' approach (1954). The use in health policy was possible due...article 2000
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Hildebrandt, V.H. (author), Proper, K.I. (author), van den Berg, R. (author), Douwes, M. (author), van den Heuvel, S.G. (author), van Buuren, S. (author), TNO Preventie en Gezondheid (author)Objective. To determine the effectiveness of a special form of exercise therapy ('Cesar therapy') on self reported recovery and improvement of posture amongst patients with chronic aspecific lower back pain. Design. Prospective randomized controlled and blinded investigation. Method. After informed consent had been obtained, patients with...article 2000
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Müller, B. (author), Björkroth, M. (author), Plitt, U. (author), Bluyssen, P.M. (author)In the beginning of 1998 a three-year European project, AIRLESS, was started to develop strategies, principles and protocols to improve and control the performance of HVAC-systems and its components for incorporation in codes and guidelines. Twelve institutes, universities and companies, from seven European countries are involved in this project...conference paper 2000
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Fleuren, M. (author), van der Meulen, M. (author), Wijkel, D. (author)Objective - To assess the relative contribution of patient and care provider characteristics to the adherence of general practitioners (GPs) and midwives to two specific recommendations in the Dutch national guidelines on imminent miscarriage. The study focused on performing physical examinations at the first contact and making a follow up...article 2000
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Bluyssen, P.M. (author), Müller, B. (author), Fitzner, K. (author)In the beginning of 1998 a three-year European project, AIRLESS, was started to develop strategies, principles and protocols to improve and control the performance of HVAC-systems and its components for incorporation in codes and guidelines. Twelve institutes, universities and companies, from seven European countries are involved in this project...conference paper 2000
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Albertini, R.J. (author), Anderson, D. (author), Douglas, G.R. (author), Hagmar, L. (author), Hemminki, K. (author), Merlo, F. (author), Natarajan, A.T. (author), Norppa, H. (author), Shuker, D.E.G. (author), Tice, R. (author), Waters, M.D. (author), Aitio, A. (author), TNO Kwaliteit van Leven TNO Bibra (author)The purpose of these guidelines is to provide concise guidance on the planning, performing and interpretation of studies to monitor groups or individuals exposed to genotoxic agents. Most human carcinogens are genotoxic but not all genotoxic agents have been shown to be carcinogenic in humans. Although the main interest in these studies is due...article 2000
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Brouwer, D.H. (author), Boeniger, M.F. (author), van Hemmen, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Hand wash and skin wipes are major techniques that have been used for dermal exposure sampling. Both techniques remove chemicals either deposited on or transferred to the skin contaminant layer by a combination of chemical and mechanical actions. The paper overviews identified methods and techniques, with emphasis on sampling parameters and...article 2000
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- van Gennip, E.M.S.J. (author), Sillevis Smitt Sr, P.A.E. (author), TNO Preventie en Gezondheid (author) article 2000
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van Leerdam, F.J.M. (author)The Youth Health Care guideline 'Early screening for hearing impairment, ages 0-19 years' draws the attention of all parties involved to the case finding of, notably, perceptive hearing loss; it helps workers in the Youth Health Care argue their referrals and improve the next steps in the process. Referrals always aim at ruling out perceptive...article 2000
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van Herten, L.M. (author), Gunning-Shepers, L.J. (author)The use of health targets as a tool in health policy is receiving more attention. Beyond political will and daring, there awaits the challenge of the fruitful use of health targets. This means an adequate response to the complexity of population health in a target structure that is transparent, controllable, and adaptable in changing...article 2000