Searched for: subject:"Growth"
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Olga, L. (author), van Diepen, J.A. (author), Bobeldijk-Pastorova, I. (author), Gross, G. (author), Prentice, S.M. (author), Snowden, S.G. (author), Furse, S. (author), Kooistra, T. (author), Hughes, I.A. (author), Schoemaker, M.H. (author), van Tol, E.A.F. (author), van Duyvenvoorde, W. (author), Wielinga, P.Y. (author), Ong, K.K. (author), Dunger, D.B. (author), Kleemann, R. (author), Koulman, A. (author)
Background: Altered lipid metabolism in early life has been associated with subsequent weight gain and predicting this could aid in obesity prevention and risk management. Here, a lipidomic approach was used to identify circulating markers for future obesity risk in translational murine models and validate in a human infant cohort. Methods:...
article 2021
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van Dommelen, P. (author)
public lecture 2021
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Spataru, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Le Masne, Q. (author), Quarteroni, S. (author), Koledova, E.B. (author)
Background: Long-term persistence of use and starting at the earliest possible age are associated with attainment of near-normal adult or final height in children who are treated with growth hormone therapy. However, there are many factors associated with a lack of persistence. Our aim was to study persistence of use in children with growth...
article 2021
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Spataru, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Le Masne, Q. (author), Quarteroni, S. (author), Koledova, E.B. (author)
Background: Suboptimal adherence to recombinant human growth hormone (r-hGH) treatment can lead to suboptimal clinical outcomes. Being able to identify children who are at risk of suboptimal adherence in the near future, and take adequate measures to support adherence, may maximize clinical outcomes. Our aim was to develop a model based on data...
article 2021
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Araujo, M. (author), van Dommelen, P. (author), Koledova, E.B. (author), Srivastava, J. (author)
The problem of consistent therapy adherence is a current challenge for health informatics, and its solution can increase the success rate of treatments. Here we show a methodology to predict, at individual-level, future therapy adherence for patients receiving daily injections of growth hormone (GH) therapy for GH deficiency. Our proposed model...
article 2021
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Wit, J.M. (author), Sas, T.C.J. (author), Ranke, M.B. (author), van Dommelen, P. (author)
Background/aims: We hypothesized that modelling catch-up growth (CUG) as developed for coeliac disease (CD), might also fit CUG in adequately treated children with juvenile hypothyroidism (JHT) or growth hormone deficiency (GHD). Methods: We used a monomolecular function for all available prepubertal data on height SDS minus target height SDS ...
article 2021
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Ruijten, P. (author), Huinink, H.P. (author), Adan, O.C.G. (author)
article 2021
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de Braaf, B. (author), Rops, C.M. (author), Storm, C. (author)
In atomic layer deposition (ALD), thin layers of materials are deposited on a substrate with atomic layer precision in the vertical direction. The ability to control layer growth in the lateral direction as well is expected to greatly increase the potential of ALD as a path to the bottom-up additive fabrication of electronic devices like solar...
article 2021
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Kant, P. (author), Koldeweij, R.B.J. (author), Harth, K. (author), van Limbeek, M.A.J. (author), Lohse, D. (author)
Freezing or solidification of impacting droplets is omnipresent in nature and technology, be it a rain droplet falling on a supercooled surface; in inkjet printing, where often molten wax is used; in additive manufacturing or metal-production processes; or in extreme ultraviolet lithography (EUV) for the chip production, where molten tin is used...
conference paper 2020
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Koledova, E. (author), Tornincasa, V. (author), van Dommelen, P. (author)
Background. Poor adherence to long-term recombinant human growth hormone (r-hGH) treatment can lead to suboptimal clinical outcomes; consequently, supporting and monitoring adherence is a crucial part of patient management. We assessed adherence to r-hGH treatment in children with growth disorders over 48 months using a connected monitoring...
article 2020
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Dommelen, P.V. (author), van Zoonen, R. (author), Vlasblom, E. (author), Wit, J.M. (author), Beltman, M. (author)
Aim To develop a guideline for preventive child healthcare professionals in order to improve early detection of pathological disorders associated with short stature (or growth faltering) or tall stature (or accelerated growth). Methods We updated the previous Dutch guideline for short stature in children aged 0‐9 years and extended it to...
article 2020
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van Dommelen, P. (author)
public lecture 2020
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Slot, H.M. (author), Nicoreac, M. (author), Maljaars, J. (author)
Rolled steel plates and sections are often applied in structures in such a way that the principal load direction corresponds with the rolling direction. Examples are beams, arches, or pylons of bridges, supporting beams of ship decks, and the main elements of crane structures. However, some types of structure are subjected to a multiaxial stress...
article 2020
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Leonetti, D. (author), Maljaars, J. (author), Snijder, H.H. (author)
article 2020
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Dragt, R.C. (author), Hengeveld, S.T. (author), Maljaars, J. (author)
Load sequence effects in fatigue crack growth, such as retardation and acceleration due to a large overload (OL) and underload (UL), can dramatically change the (remaining) fatigue life. These effects can be determined using analytical and numerical tools, often trading accuracy for a steep increase in required calculation time. This paper...
article 2020
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Maljaars, J. (author), Tang, L. (author)
Crack closure effects during fatigue crack growth have been studied by many researchers with the finite element method, but appears difficult to accurately predict. Although quantification of crack closure may be a bridge too far, finite element models may help explaining observations from tests and give insight into trends. This paper studies...
article 2020
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Pijpers, R.J.M. (author), Verdenius, S.A. (author), Abspoel-Bukman, L.M. (author), Maljaars, J. (author)
This experimental study considers load sequence effects in fatigue crack growth in coupon specimens and in element specimens. The coupon specimens were standard edge crack configurations cyclically loaded under four point bending on base metal and welds, whereas the element specimens were full-scale axially loaded tubular joints. Whereas load...
article 2020
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Ruijten, P. (author), Huinink, H.P. (author), Adan, O.C.G. (author)
Fungal growth often appears in a surrounding where water and nutrients are scarce. The impact of this environment during sporogenesis on subsequent growth is often neglected.This study investigates the effect of water availability during sporogenesis on subsequent early growth. Therefore, a carbon-depleted substrate was constructed. Humidity is...
article 2020
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Dekker, R. (author), van der Meer, F.P. (author), Maljaars, J. (author), Sluys, L.J. (author)
Structures are subjected to cyclic loads that can vary in direction and magnitude, causing constant amplitude mode I simulations to be too simplistic. This study presents a new approach for fatigue crack propagation in ductile materials that can capture mixed-mode loading and overloading. The extended finite element method is used to deal with...
article 2019
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Harsha, S. (author), Khakharia, P. (author), Huizinga, A. (author), Monteiro, J. (author), Goetheer, E. (author), Vlugt, T.J.H. (author)
The amine-based post combustion carbon capture process is one of the most advanced and preferred technologies to reduce CO 2 emissions from point sources like power plants. The emissions of amine from capture plants is one of the biggest challenges faced by this technology. These emissions typically occur by means of aerosol/mist formation. To...
article 2019
Searched for: subject:"Growth"
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