Searched for: subject%3A%22Growth%22
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van Dommelen, P. (author), Wit, J.M. (author), van Zoonen, R. (author), Vlasblom, E. (author), Beltman, M. (author)
public lecture 2022
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van Dommelen, P. (author)
public lecture 2022
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Spataru, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Le Masne, Q. (author), Quarteroni, S. (author), Koledova, E.B. (author)
Background. Our aim was to develop a machine learning model, using real-world data captured from a connected auto-injector device and from early indicators from the first 3 months of treatment, to predict sub-optimal adherence to recombinant human growth hormone (r-hGH) in patients with growth disorders. Methods. Adherence to r-hGH treatment was...
article 2022
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Morgan, K. (author), van Dommelen, P. (author), Batista, A.R. (author), Koledova, E. (author)
We explored whether a multi-component approach - using a digital health device, the easypod™ auto-injector, the 'MySupport' patient support programme (PSP) and a Patient Activation Measure® (PAM®) - could improve adherence in patients receiving recombinant human growth hormone (r-hGH). A 13-item PAM was used to assess caregiver self-reported...
bookPart 2022
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Savage, M.O. (author), Fernandez-Luque, L. (author), Graham, S. (author), van Dommelen, P. (author), Araujo, M. (author), de Arriba, A. (author), Koledova, E. (author)
Pediatric growth hormone (GH) deficiency is a licensed indication for replacement therapy with recombinant human growth hormone (r-hGH). Treatment, consisting of daily subcutaneous injections, extends from the time of diagnosis until cessation of linear growth at completion of puberty. Suboptimal adherence to r-hGH therapy is common and has been...
article 2022
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Tornincasa, V. (author), Dixon, V. (author), Le Masne, Q. (author), Martin, B. (author), Arnaud, L. (author), van Dommelen, P. (author), Koledova, E. (author)
Digital health has seen rapid advancements over the last few years in helping patients and their healthcare professionals better manage treatment for a variety of illnesses, including growth hormone (GH) therapy for growth disorders in children and adolescents. For children and adolescents requiring such therapy, as well as for their parents,...
article 2022
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von Benda-Beckmann, A.M. (author), Ketten, D.R. (author), Lam, F.P.A. (author), de Jong, C.A.F. (author), Muller, R.A.J. (author), Kastelein, R.A. (author)
Application of a kurtosis correction to frequency-weighted sound exposure level (SEL) improved predictions of risk of hearing damage in humans and terrestrial mammals for sound exposures with different degrees of impulsiveness. To assess whether kurtosis corrections may lead to improved predictions for marine mammals, corrections were applied to...
article 2022
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Assefi, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Otero, C. (author), Fernandez-Luque, L. (author), Koledova, E. (author), Calliari, L.E. (author)
Background: Recombinant human growth hormone (rhGH) therapy is an effective treatment for children with growth disorders. However, poor outcomes are often associated with suboptimal adherence to treatment. Objective: The easypod connected injection device records and transmits injection settings and dose data from patients receiving rhGH. In...
article 2022
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van Dommelen, P. (author), van Zoonen, R. (author), Vlasblom, E. (author), Wit, J.M. (author), Beltman, M. (author)
AIMS: To develop a guideline for preventive child healthcare (PCHC) professionals in order to improve early detection of pathological disorders associated with short stature (or growth faltering) or tall stature (or accelerated growth). Target groups include primary growth disorders (e.g. dysmorphic syndromes, such as Turner, Noonan, Prader...
conference paper 2022
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van Dommelen, P. (author), Arnaud, L. (author), Koledova, E.B. (author)
Curve matching may be used to predict growth outcomes using data of patients whose growth curves resemble those of a new patient with growth hormone deficiency (GHD) and those born small for gestational age (SGA). We aimed to investigate the validity of curve matching to predict growth in patients with GHD and those born SGA receiving...
article 2022
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Eekhout, I. (author), van Buuren, S. (author), Verkerk, P. (author)
There are many milestones available to measure child development in the first years of life. For less experienced professionals it is difficult to select the most relevant milestones to assess the developmental status of a child. Moreover, using the milestones separately makes is difficult to get a global impression of the developmental status....
public lecture 2022
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Eekhout, I. (author), van Buuren, S. (author)
Session Keynote. Healthy growth and development in young children are essential for their future well-being. Professionals and parents consider it necessary to monitor children’s development. While we can track the child’s physical growth by growth charts to identify children with signs of potential delay, there are no charts for monitoring...
public lecture 2022
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Ruijten, P. (author), Huinink, H.P. (author), Adan, O.C.G. (author)
article 2021
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de Braaf, B. (author), Rops, C.M. (author), Storm, C. (author)
In atomic layer deposition (ALD), thin layers of materials are deposited on a substrate with atomic layer precision in the vertical direction. The ability to control layer growth in the lateral direction as well is expected to greatly increase the potential of ALD as a path to the bottom-up additive fabrication of electronic devices like solar...
article 2021
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van Dommelen, P. (author)
public lecture 2021
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Dekker, R. (author), van der Meer, F.P. (author), Maljaars, J. (author), Sluys, L.J. (author)
This study presents calibration and validation of a cohesive extended finite element model for fatigue crack propagation in ductile materials. The approach relies on a separation between plasticity around the crack tip and fatigue crack growth at the crack tip such that the influence of plasticity on fatigue driving forces is predicted. This...
article 2021
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Spataru, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Le Masne, Q. (author), Quarteroni, S. (author), Koledova, E.B. (author)
Background: Long-term persistence of use and starting at the earliest possible age are associated with attainment of near-normal adult or final height in children who are treated with growth hormone therapy. However, there are many factors associated with a lack of persistence. Our aim was to study persistence of use in children with growth...
article 2021
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Olga, L. (author), van Diepen, J.A. (author), Bobeldijk-Pastorova, I. (author), Gross, G. (author), Prentice, S.M. (author), Snowden, S.G. (author), Furse, S. (author), Kooistra, T. (author), Hughes, I.A. (author), Schoemaker, M.H. (author), van Tol, E.A.F. (author), van Duyvenvoorde, W. (author), Wielinga, P.Y. (author), Ong, K.K. (author), Dunger, D.B. (author), Kleemann, R. (author), Koulman, A. (author)
Background: Altered lipid metabolism in early life has been associated with subsequent weight gain and predicting this could aid in obesity prevention and risk management. Here, a lipidomic approach was used to identify circulating markers for future obesity risk in translational murine models and validate in a human infant cohort. Methods:...
article 2021
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Wit, J.M. (author), Sas, T.C.J. (author), Ranke, M.B. (author), van Dommelen, P. (author)
Background/aims: We hypothesized that modelling catch-up growth (CUG) as developed for coeliac disease (CD), might also fit CUG in adequately treated children with juvenile hypothyroidism (JHT) or growth hormone deficiency (GHD). Methods: We used a monomolecular function for all available prepubertal data on height SDS minus target height SDS ...
article 2021
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Spataru, A. (author), van Dommelen, P. (author), Arnaud, L. (author), Le Masne, Q. (author), Quarteroni, S. (author), Koledova, E.B. (author)
Background: Suboptimal adherence to recombinant human growth hormone (r-hGH) treatment can lead to suboptimal clinical outcomes. Being able to identify children who are at risk of suboptimal adherence in the near future, and take adequate measures to support adherence, may maximize clinical outcomes. Our aim was to develop a model based on data...
article 2021
Searched for: subject%3A%22Growth%22
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