Searched for: subject%3A%22Glucocorticoid%255C%2Breceptor%22
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TNO Kwaliteit van Leven (author), Finken, M.J.J. (author)
Children born small-for-gestational-age (SGA) are at risk for short stature, and cardiovascular disease and type 2 diabetes in later life. There is some preliminary evidence for a similar phenotype in survivors of preterm birth. In contrast to children born SGA, preterm infants born appropriate-for-gestational-age who experienced neonatal growth...
doctoral thesis 2007
Visser, J. (author), Lentjes, E. (author), Haspels, I. (author), Graffelman, W. (author), Blauw, B. (author), de Kloet, R. (author), Nagelkerken, L. (author), TNO Preventie en Gezondheid (author)
Background: In this study we tested the hypothesis that the increased sensitivity to glucocorticoids in chronic fatigue syndrome (CFS)-patients can be attributed to an altered functioning of their glucocorticoid receptors (GR). Methods: For this purpose, affinity and distribution of the GR were studied in purified, peripheral blood mononuclear...
article 2001
Nijhuis, E.W.P. (author), Oostervink, F. (author), Hinloopen, B. (author), Rozing, J. (author), Nagelkerken, L. (author), Gaubius Instituut TNO (author)
Peripheral blood mononuclear cells (PBMC) from 40 consecutive patients entering a screening program on cognitive impairment were studied in vitro with respect to their sensitivity to dexamethasone (DEX). Phytohemagglutinin-induced proliferation by PBMC from patients with senile dementia of the Alzheimer type (SDAT) was less sensitive to the...
article 1996