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- Centraal Instituut voor Voedingsonderzoek TNO (author), Arts, J.H.E. (author) doctoral thesis 2001
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- Centraal Instituut voor Voedingsonderzoek TNO (author), Krul, C.A.M. (author) doctoral thesis 2001
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- Boelsma, E. (author), Anderson, C. (author), Karlsson, A.M.J. (author), Ponec, M. (author) article 2000
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Rodenburg, R.J.T. (author), Ganga, A. (author), van Lent, P.L.E.M. (author), van de Putte, L.B.A. (author), van Venrooij, W.J. (author)Objective. Sulfasalazine (SSZ) is a commonly used drug in the treatment of inflammatory diseases such as rheumatoid arthritis and Crohn's disease. In both diseases, the proinflammatory cytokine tumor necrosis factor α (TNFα) plays a prominent role. In these studies, we investigated the mechanism by which SSZ inhibits TNFα expression in...article 2000
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Krul, C.A.M. (author), Luiten-Schuite, A. (author), Baan, R. (author), Verhagen, H. (author), Mohn, G. (author), Feron, V. (author), Havenaar, R. (author)The TNO gastro-Intestinal tract Model (TIM) is a dynamic computer-controlled in vitro system that mimics the human physiological conditions in the stomach and small intestine. In the current TIM physiological parameters such as pH, temperature, peristaltic movements, secretion of digestion enzymes, bile and pancreatic juices, and absorption of...article 2000
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- Gibney, M.J. (author), Serra-Majem, L. (author), Kearney, J.M. (author), Becker, W. (author), Löwik, M.R.H. (author) article 2000
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- Zeijdner, E.E. (author), Havenaar, R. (author) article 2000
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Krasevec, N. (author), van de Hondel, C.A.M.J.J. (author), Komel, R. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)A gene-fusion expression strategy was applied for heterologous expression of human lymphotoxin alpha (LTα) in the Aspergillus niger AB1.13 protease-deficient strain. The LTα gene was fused with the A. niger glucoamylase GII-form as a carrier-gene, behind its transcription control and secretion signals. Special attention was paid to the influence...article 2000
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- Tüdös, A.J. (author), Stigter, E.C.A. (author), van Hövel tot Westerflier, S.W.F.M. (author), van der Gaag, A. (author), Gaspari, M. (author) article 2000
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- Brussaard, T. (author), Erp-Baart, M.-A. (author), Brants, H. (author), Hulshof, K. (author), Löwik, M. (author) article 2000
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- Louwman, M.W.J. (author), van Dusseldorp, M. (author), van de Vijver, F.J.R. (author), Thomas, C.M.G. (author), Schneede, J. (author), Ueland, P.M. (author), Refsum, H. (author), van Staveren, W.A. (author) article 2000
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Bemelmans, W.J.E. (author), Broer, J. (author), de Vries, J.H.M. (author), Hulshof, K.F.A.M. (author), May, J.F. (author), Meyboom-de Jong, B. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Objective: To investigate the impact of intensive group education on the Mediterranean diet on dietary intake and serum total cholesterol after 16 and 52 weeks, compared to a posted leaflet with the Dutch nutritional guidelines, in the context of primary prevention of cardiovascular disease (CVD). Design: Controlled comparison study of an...article 2000
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- Carpentier, P. (author), Foquin, A. (author), Rondouin, G. (author), Lerner-Natoli, M. (author), de Groot, D.M.G. (author), Lallement, G. (author) article 2000
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- Botma, Y. (author) article 2000
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- Huisman, I.H. (author), Prádanos, P. (author), Hernández, A. (author) article 2000
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- Goldbohm, R.A. (author), Voorrips, L.E. (author), Centraal Instituut voor Voedingsonderzoek TNO (author) article 2000
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Willems, J.H.B.M. (author)Sociaal geneeskundigen vervullen een belangrijke rol op het grensvlak van curatief werkende artsen en niet-medici zoals arbeidshygiënisten en psychologen. Zij nemen een geheel eigen plaats in in het veld van arbeid en gezondheid. Het College voor Sociale Geneeskunde heeft ter verhoging van de kwaliteit van de beroepsuitoefening initiatieven...article 2000
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- Reus, K.E.H. (author), Houben, G.F. (author), Stam, M. (author), Dubois, A.E.J. (author) article 2000
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- Price, R.J. (author), Surry, D. (author), Renwick, A.B. (author), Meneses-Lorente, G. (author), Lake, B.G. (author), Evans, D.C. (author) article 2000
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Botterweck, A.A.M. (author), Verhagen, H. (author), Goldbohm, R.A. (author), Kleinjans, J. (author), van den Brandt, P.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Both carcinogenic and anticarcinogenic properties have been reported for the synthetic antioxidants butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). The association between dietary intake of BHA and BHT and stomach cancer risk was investigated in the Netherlands Cohort Study (NLCS) that started in 1986 among 120,852 men and...article 2000