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Degenhardt, C.E.A.M. (author), Kientz, C.E. (author), TNO Prins Maurits Laboratorium (author)The use of large volume injections has been studied for the verification of intact organophosphorus chemical warfare agents in water samples. As the use of ethyl acetate caused severe detection problems new potential solvents were evaluated. With the developed procedure, the nerve agents sarin, tabun, soman, DFP and VX can be determined in...article 1996
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TNO Prins Maurits Laboratorium (author), Langenberg, J.P. (author), de Jong, L.P.A. (author), Benschop, H.P. (author)Several p-nitrophenyl phosphoramidates with the general formula RO(NH2)P(O)OC6H4-p-NO2, in which R = CH2CH3, CH2CH2F, CH2CHF2, CH2CF3, CH2CH2CH2CH3, and CH2CH2Cl, as well as (NH2)2P(O)OC6H4-p-NO2 were administered intravenously to guinea pigs as pretreatment compounds for protection against the lethal effects of 1,2,2-trimethylpropyl...article 1996
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Prins Maurits Laboratorium TNO (author), Wolthuis, O.L. (author), Groen, B. (author), Busker, R.W. (author), van Helden, H.P.M. (author)To investigate at which dose levels undesirable effects started, behavioural performance and several physiological parameters were measured in marmosets (Callithrix Jacchus) after soman (1.75 and 3.5 μg/kg), sarin (3 and 6 μg/kg), physostigmine (10 and 20 μg/kg), and pyridostigmine (200 and 400 μg/kg). Effects on performance were investigated...article 1995