Prins Maurits Laboratorium TNO (author), Johnson, M.K. (author), Willems, J.L. (author), de Bisschop, H.C. (author), Read, D.J. (author), Benschop, H.P. (author) Organophosphorus-induced delayed polyneuropathy (OPIDP) is thought to result from organophosphorylation of neuropathy target esterase (NTE; formerly known as neurotoxic esterase), followed by an “aging” of the phosphorylated NTE. Protection against OPIDP should thus be achieved by production of an inhibited but “nonaging” NTE. Inhibited NTE...
article 1988