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- Geertman, E.J.M. (author) doctoral thesis 1992
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Min. SZW, Arbeidsinspectie (author), Lotens, W.A. (author), van de Linde, F.J.G. (author), Havenith, G. (author)Verslag van een onderzoek naar afkoelen van de handen bij het hanteren van koude materialen of het verrichten van fysiek werk in een koude omgeving. Het onderzoeksrapport is opgebouwd in 3 delen. In deel I ('Contact met koude materialen') is een experiment uitgevoerd met 12 proefpersonen, waarbij de afkoelsnelheid van hun handen werd gemeten bij...book 1992
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Nederlands Instituut voor Praeventieve Gezondheidszorg (author), Opmeer, C.H.J.M. (author), Wientjes, C.J.E. (author), Blom, D.H.J. (author), Pokorny, M.L.I. (author), Gaillard, A.W.K. (author)Rapportage over het tweede veldonderzoek in de derde fase van het onderzoek.report 1992
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- Instituut voor Biotechnologie en Chemie TNO (author), Wolters, M.G.E. (author) doctoral thesis 1992
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Instituut CIVO-Toxicologie en Voeding TNO (author), Groten, J.P. (author), Luten, J.B. (author), van Bladeren, P.J. (author)It has been shown that addition of extra calcium/phosphorus (Ca/P), zinc (Zn) and iron (Fe2+) to the diet results in a significant protection against cadmium (Cd) accumulation and toxicity in rats fed inorganic Cd salt. However, it is not clear whether the presence of these mineral supplements in the diet also protects against the Cd uptake from...article 1992
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Instituut CIVO-Toxicologie en Voeding TNO (author), Gorgels, W.J.M.J. (author), van Poppel, G. (author), Jarvis, M.J. (author), Stenhuis, W. (author), Kok, F.J. (author)The object of this study was to determine whether exposure to environmental tobacco smoke is associated with DNA damate reflected by the frequency of sister-chromatid exchange (SCE) in lymphocytes. Within a cross-sectional design, 106 male non-smoking adults, employees of two administrative companies, were divided on the basis of self-reported...article 1992
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Instituut CIVO-Toxicologie en Voeding TNO (author), Arts, C.J.M. (author), Govers, C.A.R.L. (author), van den Berg, H. (author), Blankenstein, M.A. (author), Thijssen, J.H.H. (author)Urinary and fecal estrogen excretion were studied in male rats fed a non-fiber wheat starch diet (dietary fiber < 1%; NF group; n = 4), a low-fiber wheat flour diet (dietary fiber 2%; LF group; n = 4) or a high-fiber wheat bran diet (dietary fiber 11.6%; HF group; n = 3). Short-term effects of the experimental diet on estrogen excretion were...article 1992
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- Snelten, H. (author), te Wierik, E. (author), Veenstra, J. (author), Schaafsma, G. (author) article 1991
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- Köhler, T. (author), Mosenthin, R. (author), den Hartog, L.A. (author), Huisman, J. (author), Verstegen, M.W.A. (author), Instituut voor Landbouwkundig Onderzoek en Biochemische Produkten TNO (author) conference paper 1991
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In vitro binding of estrogens by dietary fiber and the in vivo apparent digestibility tested in pigsArts, C.J.M. (author), Govers, C.A.R.L. (author), van den Berg, H. (author), Wolters, M.G.E. (author), van Leeuwen, P. (author), Thijsen, J.H. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)Within the framework of experiments related to the association between dietary fiber and breast cancer an in vitro test system was used to study the binding of estrogens to various fibers (e.g. cholestyramin, lignin and cellulose) and fiber sources (e.g. wheat bran, cereals, seeds and legumes). Furthermore, the in vivo apparent digestibility of...article 1991
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Löwik, M.R.H. (author), Hofman, Z. (author), Kok, F.J. (author), Wedel, M. (author), Hulshof, K.F.A.M. (author), Odink, J. (author), Schaafsma, G. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)Associations between blood pressure and nutrition-related variables (body mass index, dietary intake, and 24-hr excretion of sodium, potassium, magnesium, and calcium in the urine) were investigated in men (n = 138) and women (n = 117) 65-79 years old not using drugs known to affect blood pressure and not on a diet. Among men, body mass index...article 1991
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den Besten, C. (author), Smink, M.C.C. (author), de Vries, E.J. (author), van Bladeren, P.J. (author)Microsomal metabolism of (1,2,4-TrCB) and (PeCB) was studied with special emphasis on the conversion-dependent covalent binding to protein and DNA. 1,2,4-TrCB was metabolized to 2,3,6- and 2,4,5-trichlorophenol, and to a lesser extent to 2,4,6- and 2,3,5-trichlorophenol, and trichlorohydroquinone. About 10% of all metabolites became covalently...article 1991
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de Vries, M. (author), Odink, J. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)A simple and sensitive method for the simultaneous measurement of 5-hydroxytryptamine and its main metabolite 5-hydroxyindoleacetic acid in rat brain is described. Brain tissue samples were only deproteinated and, without further extraction, were injected directly onto a high-performance liquid chromatography column and detected...article 1991
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Nederlands Instituut voor Praeventieve Gezondheidszorg TNO Preventie en Gezondheid TNO-Gezondheidsonderzoek (author), Meijst, W.J. (author), Dul, J. (author)In de huidige maatschappij maken lichamelijk zware werkzaamheden steeds meer plaats voor lichtere werkzaamheden. Dit lichte werk is tevens meestal statisch van karakter, terwijl het zware werk meer dynamisch is. Tijdens licht statisch werk raken de spieren niet uitgeput, zoals bij zwaar lichamelijk werk, maar raken ze wel vermoeid. Op de lange...report 1991
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Nederlands Instituut voor Praeventieve Gezondheidszorg TNO Preventie en Gezondheid (author), Bloem, P.J.N. (author), van der Hofstede, J.W. (author)Volgens één van de hypotheses uit het onderzoek van het Bureau Ontwikkeling Automatiseringsprojecten van de Rijksbelastingen (BOA) bestaat er verschil in het fysiologisch reageren tussen de groep mensen die veel en de groep mensen die weinig aan stress op het werk onderhevig is. Dit verschil zou zich uiten in de baroreceptorgevoeligheid (BRSI)....report 1991
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- Instituut voor Toxicologie en Voeding TNO (author), Oostveen, C.M.A. (author) doctoral thesis 1991
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- Heij. D.G. van der, (author) article 1991
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van 't Veer, P. (author), Kolb, C.M. (author), Verhoef, P. (author), Kok, F.J. (author), Schouten, E.G. (author), Hermus, R.J.J. (author), Sturmans, F. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)To study the association between dietary fiber, beta-carotene and breast cancer, the average daily intake of these dietary components was compared among 133 incident breast cancer cases and 238 population controls. Average daily intake of cereal products, fruit and vegetables was also studied. A statistically significant lower energy-adjusted...article 1990
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van Veelen, P.A. (author), Tjaden, U.R. (author), van der Greef, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)A simple method of improving signal-to-noise ratios in plasma-desorption mass spectrometry of femtomole quantities is described. Background reduction is achieved by effectively shielding of the non-sample area. It is shown that detection limits can be improved by a factor of 4. Copyright © 1990 Heyden & Son Limitedarticle 1990
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van Dokkum, W. (author), Schrijver, J. (author), Wesstra, J.A. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)The biological variability of the values of various biochemical indices used for the assessment of the nutritional status of man was investigated in 4 healthy male volunteers (mean age 23 years). They were given a constant diet for 60 d, with the nutrient intake at the level of the Dutch recommendations. Blood was collected twice a week and 24-h...article 1990