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Bobeldijk, I. (author), Boonzaaijer, G. (author), Spies-Faber, E.J. (author), Vaes, W.H.J. (author), TNO Kwaliteit van Leven (author)Reversed-phase liquid chromatography and detection with atmospheric pressure chemical ionisation tandem mass spectrometry was used for the determination of kava extracts in herbal mixtures. One percent of kava extract can be detected, corresponding to approximately 0.05-0.2 mg/g of the individual kava lactones kavain, dihydrokavain, yangonin,...article 2005
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Adams, T.B. (author), Cohen, S.M. (author), Doull, J. (author), Feron, V.J. (author), Goodman, J.I. (author), Marnett, L.J. (author), Munro, I.C. (author), Portoghese, P.S. (author), Smith, R.L. (author), Waddell, W.J. (author), Wagner, B.M. (author), TNO Kwaliteit van Leven (author)This publication is the ninth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the Panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavoring substances under conditions of intended use. Elements that are fundamental to the...article 2005
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Adams, T.B. (author), Cohen, S.M. (author), Doull, J. (author), Feron, V.J. (author), Goodman, J.I. (author), Marnett, L.J. (author), Munro, I.C. (author), Portoghese, P.S. (author), Smith, R.L. (author), Waddell, W.J. (author), Wagner, B.M. (author), TNO Kwaliteit van Leven (author)This publication is the eighth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In 1993, the panel initiated a comprehensive program to re-evaluate the safety of more than 1700 GRAS flavoring substances under conditions of intended use. Elements that are fundamental to...article 2005
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Fox, T.E. (author), van den Heuvel, E.G.H.M. (author), Atherton, C.A. (author), Dainty, J.R. (author), Lewis, D.J. (author), Langford, N.J. (author), Crews, H.M. (author), Luten, J.B. (author), Lorentzen, M. (author), Sieling, F.W. (author), van Aken-Schneyder, P. (author), Hoek, M. (author), Kotterman, M.J.J. (author), van Dael, P. (author), Firweather-Tail, S.J. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)Objective: To measure the bioavailability of selenium from cooked and raw fish in humans by estimating and comparing apparent absorption and retention of selenium in biosynthetically labelled fish with labelled selenate and biosynthetically labelled selenium in brewers yeast. Design: The intervention study was a parallel, randomised, reference...article 2004
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König, A. (author), Cockburn, A. (author), Crevel, R.W.R. (author), Debruyne, E. (author), Grafstroem, R. (author), Hammerling, U. (author), Kimber, I. (author), Knudsen, I. (author), Kuiper, H.A. (author), Peijnenburg, A.A.C.M. (author), Penninks, A.H. (author), Poulsen, M. (author), Schauzu, M. (author), Wal, J.M. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)This paper provides guidance on how to assess the safety of foods derived from genetically modified crops (GM crops); it summarises conclusions and recommendations of Working Group 1 of the ENTRANSFOOD project. The paper provides an approach for adapting the test strategy to the characteristics of the modified crop and the introduced trait, and...article 2004
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van den Eede, G. (author), Aarts, H. (author), Buhk, H.J. (author), Corthier, G. (author), Flint, H.J. (author), Hammes, W. (author), Jacobsen, B. (author), Midtvedt, T. (author), van der Vossen, J. (author), von Wright, A. (author), Wackernagel, W. (author), Wilcks, A. (author), TNO Voeding (author)In 2000, the thematic network ENTRANSFOOD was launched to assess four different topics that are all related to the testing or assessment of food containing or produced from genetically modified organisms (GMOs). Each of the topics was linked to a European Commission (EC)-funded large shared cost action (see http://www.entransfood.com). Since the...article 2004
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Koppelman, S.J. (author), Lakemond, C.M.M. (author), Vlooswijk, R. (author), Hefle, S.L. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)Several tests for the detection of soy proteins in foods have been described in the literature, and some are commercially available. This article gives an overview of these methods and discusses the advantages and disadvantages of each individual method. Based on the conclusions of this inventory, an experimental approach was designed to improve...article 2004
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Spaenij-Dekking, E.H.A. (author), Kooy-Winkelaar, E.M.C. (author), Nieuwenhuizen, W.F. (author), Drijfhout, J.W. (author), Koning, F. (author), TNO Voeding (author)Background: It is now generally accepted that coeliac disease (CD) is caused by inflammatory T cell responses to gluten peptides bound to HLA-DQ2 or -DQ8 molecules. There is overwhelming evidence that CD patients can mount T cell responses to peptides found in both α-gliadin and γ-gliadin molecules. Assays that would detect the presence or...article 2004
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López-Cervantes, L. (author), Sánchez-Machado, D.I. (author), Pastorelli, S. (author), Rijk, R. (author), Paseiro-Losada, P. (author), TNO Voeding (author)The behaviour of two commercial oxygen-scavenging products with respect to migration of active ingredients into foodstuffs was investigated. Migrants were identified, and by using appropriate analytical methods, migration was determined in a variety of liquid, solid or gelled food simulants and foods. Simulants were chosen to cover a range of...article 2003
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de Wijk, R.A. (author), van Gemert, L.J. (author), Terpstra, M.E.J. (author), Wilkinson, C.L. (author), TNO Voeding (author)A trained panel developed a set of sensory attributes describing flavor, odor, mouth feel and after feel sensations elicited by commercially available vanilla custard desserts. Two main sensory dimensions, one running from "melting" to "thick" and another one running from "rough" to "creamy-soft" could be recognized in the resulting sensory...article 2003
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Zerdin, K. (author), Rooney, M.L. (author), Vermuë, J. (author), TNO Voeding (author)A storage study of orange juice packed in oxygen scavenging (OS) film and oxygen barrier film was conducted to determine the extent of ascorbic acid loss due to oxygen as a function of time and temperature. The initial concentration of ascorbic acid in the orange juice was 374 mg/l and this was found to decrease by 74 and 104 mg/l after 3 days...article 2003
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van der Gaag, B. (author), Spath, S. (author), Dietrich, H. (author), Stigter, E. (author), Boonzaaijer, G. (author), van Osenbruggen, T. (author), Koopal, K. (author)An immunochemical biosensor assay for the detection of multiple mycotoxins in a sample is described.The inhibition assay is designed to measure four different mycotoxins in a single measurement, following extraction, sample clean-up and incubation with an appropriate cocktail of anti-mycotoxin antibodies.The different mycotoxins could be...article 2003
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van den Brandt, P.A. (author), Botterweck, A.A.M. (author), Goldbohm, R.A. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)Objective: Many case-control studies have reported that salt and cured meat intake are positively, and refrigerator use is inversely, associated with stomach cancer risk. In the current prospective study these associations were evaluated. Methods: The Netherlands Cohort Study consisted of 120,852 men and women ages 55-69 years at baseline in...article 2003
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de Jong, A.E.I. (author), Eijhusen, G.P. (author), Brouwer-Post, E.J.F. (author), Grand, M. (author), Johansson, T. (author), Kärkkäinen, T. (author), Marugg, J. (author), in 't Veld, P.H. (author), Warmerdam, F.H.M. (author), Wörner, G. (author), Zicavo, A. (author), Rombouts, F.M. (author), Beumer, R.R. (author)Many media have been developed to enumerate Clostridium perfringens from foods. In this study, six media [iron sulfite (IS) agar, tryptose sulfite cycloserine (TSC) agar, Shahidi Ferguson perfringens (SFP) agar, sulfite cycloserine azide (SCA), differential clostridial agar (DCA), and oleandomycin polymyxin sulfadiazine perfringens (OPSP) agar]...article 2003
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TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author), Kiely, M. (author), Faughnan, M. (author), Wähälä, K. (author), Brants, H. (author), Mulligan, A. (author)The objective of the Vegetal Estrogens in Nutrition and the Skeleton (VENUS) project was to evaluate existing data on dietary exposure to compounds with oestrogenic and anti-oestrogenic effects present in plant foods as constituents or contaminants, and to identify and disseminate in vitro and in vivo methodologies to analyse the effects of such...article 2003
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Impens, S. (author), de Brabander, H.F. (author), Bergwerff, A.A. (author), van Ginkel, L.A. (author), Schilt, R. (author), Stephany, R.W. (author), de Wasch, K. (author), Courtheyn, D. (author), van Peteghem, C. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Every other year scientists working in the field of residue analysis participate the "International Symposium on Hormone and Veterinary Drug Residue Analysis" and "Euroresidue" conferences. In each symposium a lot of innovative information is presented. In order to obtain a retrieval system for this growing amount of information, a database...article 2002
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Ireland, J. (author), Erp-Baart, A.M.J. (author), Charrondière, U.R. (author), Moller, A. (author), Smithers, G. (author), Trichopoulou, A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Objective: To harmonize food classification and food composition databases, allowing comparability of consumption at both food and nutrient levels in Europe. Design: To establish the level of comparability at the food level, the EFCOSUM group benefited from the work already carried out within other European projects, which established a Euro...article 2002
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Brussaard, J.H. (author), Johansson, L. (author), Kearney, J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Objective: To describe the rationale and methods for a European project (EFCOSUM) to develop a method for a European food consumption survey that delivers internationally comparable data on a set of policy-relevant nutritional indicators. Rationale and methods: Currently Member States are collecting data and information for use at national level...article 2002
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Kroes, R. (author), Müller, D. (author), Lambe, J. (author), Löwik, M.R.H. (author), van Klaveren, J. (author), Kleiner, J. (author), Massey, R. (author), Mayer, S. (author), Urieta, I. (author), Verger, P. (author), Visconti, A. (author)Exposure assessment is one of the key parts of the risk assessment process. Only intake of toxicologically significant amounts can lead to adverse health effects even for a relatively toxic substance. In the case of chemicals in foods this is based on three major aspects: (i) how to determine quantitatively the presence of a chemical in...article 2002
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van Duijn, G. (author), van Biert, R. (author), Bleeker-Marcelis, H. (author), van Boeijen, I. (author), Adan, A.J. (author), Jhakrie, S. (author), Hessing, M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)According to European Commission (EC) Regulation 1139/98, foods and food ingredients that are to be delivered to the final consumer in which either protein or DNA resulting from genetic modification is present, shall be subject to additional specific labeling requirements. Since 1994, genetically altered tomatoes, squash, potatoes, canola,...article 2002