Searched for: subject%3A%22Fetus%255C%2Bdevelopment%22
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Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)
Due to ever-improving medical technology over the course of the last century, the limit of viability has been lowered from around 32 weeks of gestation, first to 28 weeks and, in recent decades, to as low as less than 24 weeks. Long-term follow-up studies (Project on Preterm and Small-for- Gestational-Age Infants, Leiden Follow-up Project on...
article 2006
Wolterbeek, A.P.M. (author), Roberts, A. (author), Korte, H. (author), Unkila, M. (author), Waalkens-Berendsen, D.H. (author), TNO Voeding (author)
Plant lignan 7-hydromatairesinol, a novel precursor of the mammalian lignan enterolactone was evaluated in a prenatal developmental toxicity study conducted in the Wistar rat. Mated female rats were fed diets containing 0, 0.25, 1, and 4% (w/w) of 7-hydroxymatairesinol in the form of potassium acetate complex (HMRlignan; potassium acetate level...
article 2004
Hooser, S.T. (author), van Dijk-Knijnenburg, C.M. (author), Waalkens-Berendsen, I.D.H. (author), Smits-van Prooije, A.E. (author), Snoeij, N.J. (author), Baan, R.A. (author), Fichtinger-Schepman, M.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Exposure of males to some genotoxic chemicals causes DNA damage in spermatozoa resulting in embryotoxicity and developmental defects in their offspring. This study demonstrates that cisplatin-DNA adducts could be measured in spermatozoa following treatment with the antineoplastic drug, cisplatin. The formation of spermatozoa cisplatin-DNA...
article 2000