Searched for: subject:"Fatty%5C+Acids"
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Pinart, M. (author), Jeran, S. (author), Boeing, H. (author), Stelmach-Mardas, M. (author), Standl, M. (author), Schulz, H. (author), Harris, C. (author), von Berg, A. (author), Herberth, G. (author), Koletzko, S. (author), Linseisen, J. (author), Breuninger, T.A. (author), Nöthlings, U. (author), Barbaresko, J. (author), Benda, S. (author), Lachat, C. (author), Yang, C. (author), Gasparini, P. (author), Robino, A. (author), Rojo-Martínez, G. (author), Castaño, L. (author), Guillaume, M. (author), Donneau, A.F. (author), Hoge, A. (author), Gillain, N. (author), Avraam, D. (author), Burton, P.R. (author), Bouwman, J. (author), Pischon, T. (author), Nimptsch, K. (author)
Background: Associations between increased dietary fat and decreased carbohydrate intake with circulating HDL and non-HDL cholesterol have not been conclusively determined. Objective: We assessed these relations in 8 European observational human studies participating in the European Nutritional Phenotype Assessment and Data Sharing Initiative ...
article 2021
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Mueller, A.M. (author), Kleemann, R. (author), Gart, E. (author), van Duyvenvoorde, W. (author), Verschuren, L. (author), Caspers, M. (author), Menke, A. (author), Krömmelbein, N. (author), Salic, K. (author), Burmeister, Y. (author), Seilheimer, B. (author), Morrison, M.C. (author)
The development of obesity is characterized by the metabolic overload of tissues and subsequent organ inflammation. The health effects of krill oil (KrO) on obesity-associated inflammation remain largely elusive, because long-term treatments with KrO have not been performed to date. Therefore, we examined the putative health effects of 28 weeks...
article 2021
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Pieterman, E.J. (author), Princen, H.M.G. (author), Jarke, A. (author), Nilsson, R. (author), Cavallin, A. (author), Bergenholm, L. (author), Henricsson, M. (author), Gopaul, V.S. (author), Agrawal, R. (author), Nissen, S.E. (author), Hurt-Camejo, E. (author)
We investigated the effects of chronic oral administration of mineral oil, versus corn oil as control, on intestinal permeability, inflammatory markers, and plasma lipids in APOE*3-Leiden.CETP mice. Mice received mineral oil or corn oil 15 or 30 μL/mouse/day for 16 weeks (15 mice/group). Intestinal permeability was increased with mineral versus...
article 2021
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van Ginneken, V. (author), Verheij, E.R. (author), de Vries, E. (author), Schouten, F. (author), van der Greef, J. (author)
There are currently two main directions with regard to nutritional supplements with PUFAs. The first research school recommends enriching the diet with the essential fatty acid (EFA) obtained from vegetable sources, the C18 lipid omega-3 molecule α-linolenic acid and then via the elongase/desaturase activity naturally in omega-3 Eicosapentaenoic...
article 2020
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Fernandez-Gutierrez, M.M. (author), Imangaliyev, S. (author), Loos, B.G. (author), Keijser, B.J.F. (author), Kleerebezem, M. (author)
unexplored.
article 2020
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Bisselink, R.J.M. (author), Crockatt, M. (author), Zijlstra, M. (author), Bakker, I.J. (author), Goetheer, E.L.V. (author), Slaghek, T.M. (author), van Es, D.S. (author)
The electrochemical production of valeric acid from the renewable bio-based feedstock levulinic acid has the potential to replace the oxo-process, which uses fossil-based feedstock 1-butylene. The electrochemical reduction of the ketone functionality in levulinic acid using lead or mercury cathodes has already been known for over 100 years....
article 2019
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Kartaram, S. (author), Mensink, M. (author), Teunis, M. (author), Schoen, E. (author), Witte, G. (author), Janssen Duijghuijsen, L. (author), Verschuren, M. (author), Mohrmann, K. (author), M'Rabet, L. (author), Knipping, K. (author), Wittink, H. (author), van Helvoort, A. (author), Garssen, J. (author), Witkamp, R. (author), Pieters, R. (author), van Norren, K. (author)
Background & aims: Plasma citrulline concentration is considered to be a marker for enterocyte metabolic mass and to reflect its reduction as may occur during intestinal dysfunction. Strenuous exercise can act as a stressor to induce small intestinal injury. Our previous studies suggest that this comprises the intestinal ability to produce...
article 2019
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Perdijk, O. (author), Baarlen, P.V. (author), Fernandez-Gutierrez, M.M. (author), Brink, E.V. (author), Schuren, F.H.J. (author), Brugman, S. (author), Savelkoul, H.F.J. (author), Kleerebezem, M. (author), Neerven, R.J.J.V. (author)
Human milk oligosaccharides (HMO) and prebiotic oligosaccharides are proposed to confer several health benefits to the infant. They shape the microbiota, have anti-inflammatory properties, and support epithelial barrier functioning. However, in order to select the best oligosaccharides for inclusion in infant formulas, there is a need to...
article 2019
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Matualatupauw, J.C. (author), O'Grada, C. (author), Hughes, M.F. (author), Roche, H.M. (author), Afman, L.A. (author), Bouwman, J. (author)
Scope: Several studies have examined the whole-genome gene expression response in blood cells to high-fat challenges with differing results. The study aims to identify consistently up- or downregulated genes and pathways in response to a high-fat challenge using several integration methods. Methods and results: Three studies measuring the gene...
article 2019
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Gart, E. (author), Souto Lima, E. (author), Schuren, F, (author), de Ruiter, C.G.F. (author), Attema, J. (author), Verschuren, L. (author), Keijer, J. (author), Salic, K. (author), Morrison, M.C. (author), Kleemann, R. (author)
Development of non-alcoholic fatty liver disease (NAFLD) is linked to obesity, adipose tissue inflammation, and gut dysfunction, all of which depend on diet. So far, studies have mainly focused on diet-related fecal microbiota changes, but other compartments may be more informative on host health. We present a first systematic analysis of...
article 2019
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Glasius, M. (author), Hansen, A.M.K. (author), Claeys, M. (author), Henzing, J.S. (author), Jedynska, A.D. (author), Kasper-Giebl, A. (author), Kistler, M. (author), Kristensen, K. (author), Martinsson, J. (author), Maenhaut, W. (author), Nøjgaard, J.K. (author), Spindler, G. (author), Stenström, K.E. (author), Swietlicki, E. (author), Szidat, S. (author), Simpson, D. (author), Yttri, K.E. (author)
Sources of elemental carbon (EC) and organic carbon (OC) in atmospheric aerosols (carbonaceous aerosols) were investigated by collection of weekly aerosol filter samples at six background sites in Northern Europe (Birkenes, Norway; Vavihill, Sweden; Risoe, Denmark; Cabauw and Rotterdam in The Netherlands; Melpitz, Germany) during winter 2013....
article 2018
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Remels, A.H.V. (author), Derks, W.J.A. (author), Cillero-Pastor, B. (author), Verhees, K.J.P. (author), Kelders, M.C. (author), Heggermont, W. (author), Carai, P. (author), Summer, G. (author), Ellis, S.R. (author), de Theije, C.C. (author), Heeren, R.M.A. (author), Heymans, S. (author), Papageorgiou, A.P. (author), van Bilsen, M. (author)
Acute viral myocarditis (VM), characterised by leukocyte infiltration and dysfunction of the heart, is an important cause of sudden cardiac death in young adults. Unfortunately, to date, the pathological mechanisms underlying cardiac failure in VM remain incompletely understood. In the current study, we investigated if acute VM leads to cardiac...
article 2018
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Carmany, D. (author), Walz, A.J. (author), Hsu, F.L. (author), Benton, B. (author), Burnett, D. (author), Gibbons, J. (author), Noort, D. (author), Glaros, T. (author), Sekowski, J.W. (author)
Organophosphorus (OP) nerve agents continue to be a threat at home and abroad during the war against terrorism. Human exposure to nerve agents such as VX results in a cascade of toxic effects relative to the exposure level including ocular miosis, excessive secretions, convulsions, seizures, and death. The primary mechanism behind these overt...
article 2017
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Könst, P.M. (author), Hernandez Mireles, I. (author), van der Stel, R.W. (author), van Os, P.M. (author), Goetheer, E.L.V. (author)
In view of its promise as sustainable process for CO2 capture and its potential in the production of feed, food and natural high value products such as omega-3 fatty acids and anti-oxidants such as astaxanthin, large scale algae cultivation is gaining commercial interest. Currently, most systems are based on directly contacting CO2 containing...
article 2017
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Hoeke, G. (author), Wang, Y. (author), van Dam, A.D. (author), Mol, M. (author), Gart, E. (author), Klop, H.G. (author), van den Berg, S.M. (author), Pieterman, E.H. (author), Princen, H.M.G. (author), Groen, A.K. (author), Rensen, P.C.N. (author), Berbée, J.F.P. (author), Boon, M.R. (author)
Background and aims Activation of brown adipose tissue (BAT) reduces both hyperlipidemia and atherosclerosis by increasing the uptake of triglyceride-derived fatty acids by BAT, accompanied by formation and clearance of lipoprotein remnants. We tested the hypothesis that the hepatic uptake of lipoprotein remnants generated by BAT activation...
article 2017
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Fluitman, K.S. (author), de Clercq, N.C. (author), Keijser, B.J.F. (author), Visser, M. (author), Nieuwdorp, M. (author), Ijzerman, R.G. (author)
Introduction: Malnutrition refers to both over- and undernutrition and results from a disruption in energy balance. It affects one in three people worldwide and is associated with increased morbidity and mortality. The intestinal microbiota represents a newly identified factor that might contribute to the development of malnutrition, as it...
article 2017
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San-Cristobal, R. (author), Navas-Carretero, S. (author), Livingstone, K.M. (author), Celis-Morales, C. (author), Macready, A.L. (author), Fallaize, R. (author), O’Donovan, C.B. (author), Lambrinou, C.P. (author), Moschonis, G. (author), Marsaux, C.F.M. (author), Manios, Y. (author), Jarosz, M. (author), Daniel, H. (author), Gibney, E.R. (author), Brennan, L. (author), Drevon, C.A. (author), Gundersen, T.E. (author), Gibney, M. (author), Saris, W.H.M. (author), Lovegrove, J.A. (author), Grimaldi, K. (author), Parnell, L.D. (author), Bouwman, J. (author), Ommen, B. (author), Mathers, J.C. (author), Alfredo Martinez, J. (author)
Mediterranean Diet (MedDiet) adherence has been proven to produce numerous health benefits. In addition, nutrigenetic studies have explained some individual variations in the response to specific dietary patterns. The present research aimed to explore associations and potential interactions between MedDiet adherence and genetic background...
article 2017
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Arnoldussen, I.A.C. (author), Zerbi, V. (author), Wiesmann, M. (author), Noordman, R.H.J. (author), Bolijn, S. (author), Mutsaers, M.P.C. (author), Dederen, P.J.W.C. (author), Kleemann, R. (author), Kooistra, T. (author), van Tol, E.A.F. (author), Gross, G. (author), Schoemaker, M.H. (author), Wieling, P.Y. (author), Kilian, A. (author)
orldwide, the incidence of obesity is increasing at an alarming rate, and the number of children with obesity is especially worrisome. These developments raise concerns about the physical, psychosocial and cognitive consequences of obesity. It was shown that early dietary intake of arachidonic acid (ARA) and docosahexaenoic acid (DHA) can reduce...
article 2016
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Stroeve, J.H.M. (author), Saccenti, E. (author), Bouwman, J. (author), Dane, A. (author), Strassburg, K. (author), Vervoort, J. (author), Hankemeier, T. (author), Astrup, A. (author), Smilde, A.K. (author), van Ommen, B. (author), Saris, W.H.M. (author)
Objective: Aim is to predict successful weight loss by metabolic signatures at baseline and to identify which differences in metabolic status may underlie variations in weight loss success. Methods: In DiOGenes, a randomized, controlled trial, weight loss was induced using a low calorie diet (800 kcal) for 8-weeks. Men (N5236) and women (N5431)...
article 2016
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Jacobs, D.M. (author), Mihaleva, V.V. (author), van Schalkwijk, D.B. (author), de Graaf, A.A. (author), Vervoort, J. (author), van Dorsten, F.A. (author), Ras, R.T. (author), Demonty, I. (author), Trautwein, E.A. (author), van Duynhoven, J. (author)
Scope: Consumption of a low-fat spread enriched with plant sterols (PS) and different low doses (<2 g/day) of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from fish oil reduces serum triglycerides (TGs) and low-density lipoprotein-cholesterol (LDL-Chol) and thus beneficially affects two blood lipid risk factors. Yet, their combined...
article 2015
Searched for: subject:"Fatty%5C+Acids"
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