Searched for: subject%3A%22Exposure%255C%2Bassessment%22
(1 - 20 of 65)

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Fransman, W. (author), Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author)
Objectives: Within the chemical legislation, REACH was implemented in order to improve safe working conditions with hazardous substances. Literature and real-life experiences by those concerned have shown that there are still gaps with a need for improved risk communication. This study elaborated on how information provided by REACH is...
article 2022
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Fransman, W. (author), Arnone, M. (author), Borghi, F. (author), Cattaneo, A. (author), Cavallo, D.M. (author), Cherrie, J.W. (author), Franken, R. (author), Galea, K.S. (author), van der Haar, R. (author), Heussen, G.A.H. (author), Jensen, K.A. (author), Koponen, M. (author), Koppisch, D. (author), Kromhout, H. (author), Luo, KY.S. (author), McNally, K. (author), Säämänen, A. (author), Spinazzè, A. (author), van Tongeren, M. (author), Jeroen, (author), Vanoirbeek, J. (author), Verpaele, S. (author), Vetter, D. (author), Viegas, S. (author), Warren, N. (author)
In this article, we have responded to the key statements in the article by Koivisto et al. (2022) that were incorrect and considered to be a biased critique on a subset of the exposure models used in Europe (i.e. ART and Stoffenmanager®) used for regulatory exposure assessment. We welcome scientific discussions on exposure modelling (as was done...
article 2022
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Jones, K. (author), Galea, K.S. (author), Scholten, B. (author), Porras, S. (author), Bousoumah, R. (author), Ndaw, S. (author), Louro, H. (author), Silva, M.J. (author), Viegas, S. (author), Godderis, L. (author), Verdonck, J. (author), Poels, K. (author), Groen, T. (author), Duca, R.C. (author), Santonen, T. (author), HBM4EU Diisocyanates Study Team, (author)
Diisocyanates have long been a leading cause of occupational asthma in Europe, and recently, they have been subjected to a restriction under the REACH regulations. As part of the European Human Biomonitoring project (HBM4EU), we present a study protocol designed to assess occupational exposure to diisocyanates in five European countries. The...
article 2022
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le Feber, M. (author), Jadoenathmisier, T. (author), Goede, H. (author), Kuijpers, E. (author), Pronk, A. (author)
Will sensor-based exposure assessment be the future in workplace settings? Static instruments with embedded sensors are already applied to monitor levels of dangerous substances-in the context of acute health effects-at critical locations. However, with wearable, lightweight, miniaturized (low-cost) sensors developing quickly, much more is...
article 2021
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Franken, R. (author), Turkenburg, J. (author), Kasiotis, K.M. (author), Shandilya, N. (author), Baan, J. (author), Tsakirakis, A.N. (author), Chartzala, I. (author), Anastasiadou, P. (author), Machera, K. (author), Rother, D. (author), Roitzsch, M. (author), Poppek, U. (author), Meyer, J. (author), Schluter, U. (author), Gerritsen-Ebben, R.M. (author), Spaan, S. (author)
Dermal exposure is an important exposure route for occupational exposure and risk assessment. A fluorescence method has been developed to quantify occupational dermal exposure based on a visualization technique, using Tinopal SWN as a fluorescent tracer. The method was developed within the framework of a large experimental study, the SysDEA...
article 2021
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Figueiredo, D.M. (author), Krop, E.J.M. (author), Duyzer, J. (author), Gerritsen-Ebben, R.M. (author), Gooijer, Y.M. (author), Holterman, H.J. (author), Huss, A. (author), Jacobs, C.M.J. (author), Kivits, C.M. (author), Kruijne, R. (author), Mol, H.J.G.J. (author), Oerlemans, A. (author), Sauer, P.J.J. (author), Scheepers, P.T.J. (author), van de Zande, J.C. (author), van den Berg, E. (author), Wenneker, M. (author), Vermeulen, R.C.H. (author)
Background: Application of pesticides in the vicinity of homes has caused concern regarding possible health effects in residents living nearby. However, the high spatiotemporal variation of pesticide levels and lack of knowledge regarding the contribution of exposure routes greatly complicates exposure assessment approaches. Objective: The...
article 2021
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Oerlemans, A. (author), Figueiredo, D.M. (author), Mol, J.G.J. (author), Nijssen, R. (author), Anzion, R.B.M. (author), van Dael, M.f.P. (author), Duyzer, J. (author), Roeleveld, N. (author), Russel, F.G.M. (author), Vermeulen, R.C.H. (author), Scheepers, P.T.J. (author)
Background: Residential exposure to pesticides may occur via inhalation of airborne pesticides, direct skin contacts with pesticide-contaminated surfaces, and consumption of food containing pesticide residues. The aim was to study the association of dermal exposure to pesticides between the use and non-use periods, between farmer and non-farmer...
article 2021
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Spaan, S. (author), Glass, R. (author), Goede, H. (author), Ruiter, S. (author), Gerritsen-Ebben, R.M. (author)
The suitability, availability, and use of protective clothing are critical factors determining the actual dermal exposure (ADE) of operators and workers to pesticides. A realistic assessment of occupational exposure to pesticides requires information about the performance of protective clothing during everyday use. In this study, the performance...
article 2020
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Kasiotis, K.M. (author), Spaan, S. (author), Tsakirakis, A.N. (author), Franken, R. (author), Chartzala, I. (author), Anastasiadou, P. (author), Machera, K. (author), Rother, D. (author), Roitzsch, M. (author), Poppek, U. (author), Lucadei, G. (author), Baumgärtel, A. (author), Schlüter, U. (author), Gerritsen-Ebben, R.M. (author)
There is a principal need for more precise methodology with regard to the determination of occupational dermal exposure. The goal of the Systematic analysis of Dermal Exposure to hazardous chemical Agents at the workplace project was therefore to generate scientific knowledge to improve and standardize measurement methods for dermal exposure to...
article 2020
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Franken, R. (author), Shandilya, N. (author), Marquart, H. (author), McNally, K. (author), Fransman, W. (author)
Measured data are generally preferred to modelled estimates of exposure. Grouping and read-across is already widely used and accepted approach in toxicology, but an appropriate approach and guidance on how to use existing exposure measurement data on one substance and work situation for another substance and/or work situation is currently not...
article 2020
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Kuijpers, E. (author), Pronk, A. (author), Koivisto, A.J. (author), Jensen, K.A. (author), Vermeulen, R. (author), Fransman, W. (author)
article 2020
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Goede, H.A. (author), McNally, K. (author), Gorce, J.P. (author), Marquart, H. (author), Warren, N.D. (author), Fransman, W. (author), Tischer, M. (author), Schinkel, J. (author)
This article describes the development of a mechanistic model for underpinning the dermal Advanced REACH Tool (dART), an extension of the existing ART model and its software platform. It was developed for hand exposure to low volatile liquids (vapour pressure ≤ 10 Pa at 20°C) including solids-in-liquid products. The model is based on an existing...
article 2019
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Huysmans, M.A. (author), Eijckelhof, B.H.W. (author), Bruno Garza, J.L. (author), Coenen, P. (author), Blatter, B.M. (author), Johnson, P.W. (author), van Dieën, J.H. (author), van der Beek, A.J. (author), Dennerlein, J.T. (author)
Objectives: Alternative techniques to assess physical exposures, such as prediction models, could facilitate more efficient epidemiological assessments in future large cohort studies examining physical exposures in relation to work-related musculoskeletal symptoms.The aim of this study was to evaluate two types of models that predict arm-wrist...
article 2018
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Fonseca, A.S. (author), Kuijpers, E. (author), Kling, K.I. (author), Levin, M. (author), Koivisto, A.J. (author), Nielsen, S.H. (author), Fransman, W. (author), Fedutik, Y. (author), Jensen, K.A. (author), Koponen, I.K. (author)
Fume hoods are one of the most common types of equipment applied to reduce the potential of particle exposure in laboratory environments. A number of previous studies have shown particle release during work with nanomaterials under fume hoods. Here, we assessed laboratory workers’ inhalation exposure during synthesis and handling of CuO, TiO2...
article 2018
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Tromp, P.C. (author), Kuijpers, E. (author), Bekker, C. (author), Godderis, L. (author), Lan, Q. (author), Jedynska, A.D. (author), Vermeulen, R. (author), Pronk, A. (author)
To date there is no consensus about the most appropriate analytical method for measuring carbon nanotubes (CNTs), hampering the assessment and limiting the comparison of data. The goal of this study is to develop an approach for the assessment of the level and nature of inhalable multi-wall CNTs (MWCNTs) in an actual workplace setting by...
article 2017
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Loh, M. (author), Sarigiannis, D. (author), Gotti, A. (author), Karakitsios, S. (author), Pronk, A. (author), Kuijpers, E. (author), Annesi-Maesano, I. (author), Baiz, N. (author), Madureira, J. (author), Fernandes, E.O. (author), Jerrett, M. (author), Cherrie, J.W. (author)
The advent of the exposome concept, the advancement of mobile technology, sensors, and the “internet of things” bring exciting opportunities to exposure science. Smartphone apps, wireless devices, the downsizing of monitoring technologies, along with lower costs for such equipment makes it possible for various aspects of exposure to be measured...
article 2017
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Coenen, P. (author), Douwes, M. (author), van den Heuvel, S. (author), Bosch, T. (author)
Occupational postures are considered to be an important group of risk factors for musculoskeletal pain. However, the exposure-outcome association is not clear yet. Therefore, we aimed to determine the exposure-outcome association of working postures and musculoskeletal symptoms. Also, we aimed to establish exposure limits for working postures....
article 2016
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Brouwer, D. (author), Boessen, R. (author), van Duuren-Stuurman, B. (author), Bard, D. (author), Moehlmann, C. (author), Bekker, C. (author), Fransman, W. (author), Entink, R.K. (author)
Tiered or stepwise approaches to assess occupational exposure to nano-objects, and their agglomerates and aggregates have been proposed, which require decision rules (DRs) to move to a next tier, or terminate the assessment. In a desk study the performance of a number of DRs based on the evaluation of results from direct reading instruments was...
article 2016
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Fransman, W. (author), Bekker, C. (author), Tromp, P. (author), Duis, W.B. (author)
Increasing production and applications of manufactured nano objects (MNOs) have become a source for human exposure and therefore raise concerns and questions about the possible health effects. In this study, the potential release of nano objects, their agglomerates, and aggregates (NOAA) as a result of sanding of hardwood treated with MNOs...
article 2016
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Bekker, C. (author), Voogd, E. (author), Fransman, W. (author), Vermeulen, R. (author)
Background: Control banding can be used as a first-tier assessment to control worker exposure to nano-objects and their aggregates and agglomerates (NOAA). In a second tier, more advanced modelling approaches are needed to produce quantitative exposure estimates. As currently no general quantitative nano-specific exposure models are available,...
article 2016
Searched for: subject%3A%22Exposure%255C%2Bassessment%22
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