Thymic factors and T cell maturation in vitro: A comparison of the effects of thymic epithelial cultures with thymic extracts and thymus dependent serum factors

In the present review the results obtained so far with thymic epithelial culture supernatants (TES) or cocultivation of potential precursor T cells with TE cells will be discussed and compared with the effects reported for other thymic factors in studies on T cell differentiation in vitro. These studies can be divided into those involved with T...

Repeated exposure to furfural vapour: 13-week study in syrian golden hamsters

The sub-acute inhalation toxicity of furfural was studied in Syrian golden hamsters. Four groups of ten males and ten females each were repeatedly exposed to furfural vapour at concentrations of 0, 20, 115 and 552 ppm (0, 77,448 and 2165 mg/m3 air) respectively for 6 hours/day, 5 days/week during a period of 13 weeks. At the highest exposure...

The regulation of cell proliferation and differentiation in intestinal epithelium. II. A quantitative histochemical and autoradiographic study after low doses of X-irradiation

To investigate the biochemical mechanisms involved in the regulation of cell proliferation and differentiation the intestinal epithelium has been chosen because of the regular distribution of proliferative-, non-dividing maturing- and functional cells along the crypt and villus. The effect of low doses of irradiation (50-400 R) which selectively...