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Kleovoulou, E.G. (author), Konstantinou, C. (author), Constantinou, A. (author), Kuijpers, E. (author), Loh, M. (author), Galea, K.S. (author), Stierum, R. (author), Pronk, A. (author), Makris, K.C. (author)Background and aim The Vasilikos Energy Center (VEC) is a large hydrocarbon industrial hub actively operating in Cyprus. There is strong public interest by the communities surrounding VEC to engage with all stakeholders towards the sustainable development of hydrocarbon in the region. The methodological framework of the exposome concept would...article 2021
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Fonseca, A.S. (author), Kuijpers, E. (author), Kling, K.I. (author), Levin, M. (author), Koivisto, A.J. (author), Nielsen, S.H. (author), Fransman, W. (author), Fedutik, Y. (author), Jensen, K.A. (author), Koponen, I.K. (author)Fume hoods are one of the most common types of equipment applied to reduce the potential of particle exposure in laboratory environments. A number of previous studies have shown particle release during work with nanomaterials under fume hoods. Here, we assessed laboratory workers’ inhalation exposure during synthesis and handling of CuO, TiO2...article 2018
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Szigeti, T. (author), Dunster, C. (author), Cattaneo, A. (author), Spinazzè, A. (author), Mandin, C. (author), Le Ponner, E. (author), de Oliveira Fernandes, E. (author), Ventura, G. (author), Saraga, D.E. (author), Sakellaris, I.A. (author), de Kluizenaar, Y. (author), Cornelissen, E. (author), Bartzis, J.G. (author), Kelly, F.J. (author)In the frame of the OFFICAIR project, office buildings were investigated across Europe to assess how the office workers are exposed to different particulate matter (PM) characteristics (i.e. PM2.5 mass concentration, particulate oxidative potential (OP) based on ascorbate and reduced glutathione depletion, trace element concentration and total...article 2017
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Szigeti, T. (author), Dunster, C. (author), Cattaneo, A. (author), Cavallo, D. (author), Spinazze, A. (author), Saraga, D.E. (author), Sakellaris, I.A. (author), de Kluizenaar, Y. (author), Cornelissen, E.J.M. (author), Hanninen, O. (author), Peltonen, M. (author), Calzolai, G. (author), Lucarelli, F. (author), Mandin, C. (author), Bartzis, J.G. (author), Zaray, G. (author), Kelly, F.J. (author)In the frame of the OFFICAIR project, indoor and outdoor PM2.5 samples were collected in office buildings acrossarticle 2016
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Dekeling, R. (author), Tasker, M. (author), Ainslie, M. (author), Andersson, M. (author), André, M. (author), Borsani, F. (author), Brensing, K. (author), Castellote, M. (author), Dalen, J. (author), Folegot, T. (author), van der Graaf, S. (author), Leaper, R. (author), Liebschner, A. (author), Pajala, J. (author), Robinson, S. (author), Sigray, P. (author), Sutton, G. (author), Thomsen, F. (author), Werner, S. (author), Wittekind, D. (author), Young, J.V. (author)The European Marine Strategy Framework Directive requires European member states to develop strategies for their marine waters leading to programs of measures that achieve or maintain good environmental status (GES) in all European seas by 2020. An essential step toward reaching GES is the establishment of monitoring programs, enabling the state...conference paper 2016
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Klein Entink, R.H. (author), Fransman, W. (author), Brouwer, D.H. (author)Measurement strategies for exposure to nano-sized particles differ from traditional integrated sampling methods for exposure assessment by the use of real-time instruments. The resulting measurement series is a time series, where typically the sequential measurements are not independent from each other but show a pattern of autocorrelation. This...article 2011
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Vogel, I. (author), Brug, J. (author), van der Ploeg, C.P.B. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)OBJECTIVE. To identify parties involved in the prevention of MP3-induced hearing loss among adolescents and potentially effective prevention strategies and interventions. METHODS. Thirty experts in fields such as scientific research, medical practice, community health professions, education, youth work, music entertainment, and enforcement...article 2009
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van Leeuwen, D.M. (author), Pedersen, M. (author), Hendriksen, P.J.M. (author), Boorsma, A. (author), van Herwijnen, M.H.M. (author), Gottschalk, R.W.H. (author), Kirsch-Volders, M. (author), Knudsen, L.E. (author), Šrám, R.J. (author), Bajak, E. (author), van Delft, J.H.M. (author), Kleinjans, J.C.S. (author), TNO Kwaliteit van Leven (author)Differences in biological responses to exposure to hazardous airborne substances between children and adults have been reported, suggesting children to be more susceptible. Aim of this study was to improve our understanding of differences in susceptibility in cancer risk associated with air pollution by comparing genome-wide gene expression...article 2008
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- van Leeuwen, K. (author), TNO Kwaliteit van Leven (author) article 2007
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Adan, O.C.G. (author), Ng-A-Tham, J. (author), Hanke, W. (author), Sigsgaard, T. (author), van den Hazel, P. (author), Wu, F. (author), TNO Bouw en Ondergrond TNO Defensie en Veiligheid (author)Increasingly, policymakers in Europe and around the world are realizing the importance of healthy indoor environments for public health. Certain member states of the European Union (EU) have already achieved successes in improving indoor environmental quality, such as controlling certain contaminants (e.g., environmental tobacco smoke) or...article 2007
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Hoek, G. (author), Brunekreef, B. (author), Goldbohm, S. (author), Fischer, P. (author), van den Brandt, P.A. (author)Background: Long-term exposure to particulate matter air pollution has been associated with increased cardiopulmonary mortality in the USA. We aimed to assess the relation between traffic-related air pollution and mortality in participants of the Netherlands Cohort study on Diet and Cancer (NLCS), an ongoing study. Methods: We investigated a...article 2002
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Feron, V.J. (author), Cassee, F.R. (author), Groten, J.P. (author), van Vliet, P.W. (author), van Zorge, J.A. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)In this article, we highlight new developments and recent studies concerning adverse human health effects related to chemical mixtures. One group of activities comprises the development of a new computer program for analyzing mixture studies and a mathematical model as a basis for combination rules that predict the toxicity of mixtures. Other...article 2002
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Albertini, R.J. (author), Anderson, D. (author), Douglas, G.R. (author), Hagmar, L. (author), Hemminki, K. (author), Merlo, F. (author), Natarajan, A.T. (author), Norppa, H. (author), Shuker, D.E.G. (author), Tice, R. (author), Waters, M.D. (author), Aitio, A. (author), TNO Kwaliteit van Leven TNO Bibra (author)The purpose of these guidelines is to provide concise guidance on the planning, performing and interpretation of studies to monitor groups or individuals exposed to genotoxic agents. Most human carcinogens are genotoxic but not all genotoxic agents have been shown to be carcinogenic in humans. Although the main interest in these studies is due...article 2000
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Passchier-Vermeer, W. (author), Passchier, W.F. (author), TNO Preventie en Gezondheid (author)Exposure to noise constitutes a health risk. There is sufficient scientific evidence that noise exposure can induce hearing impairment, hypertension and ischemic heart disease, annoyance, sleep disturbance, and decreased school performance. For other effects such as changes in the immune system and birth defects, the evidence is limited. Most...article 2000
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Anderson, C.A. (author), Copestake, P.T. (author), Robinson, L. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The retrieval precision and recall of a specialist bibliographic toxicity database (TRACE) and a range of widely available bibliographic databases used to identify toxicity papers were compared. The analysis indicated that the larger size and resources of the major bibliographic databases did not, for a series of test queries, assure superior...article 2000
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TNO Preventie en Gezondheid (author), van Maanen, J.M.S. (author), Albering, H.J. (author), de Kok, T.M.C.M. (author), van Breda, S.G.J. (author), Curfs, D.M.J. (author), Vermeer, I.T.M. (author), Ambergen, A.W. (author), Wolffenbuttel, B.H.R. (author), Kleinjans, J.C.S. (author), Reeser, H.M. (author)In recent years, several studies have addressed a possible relationship between nitrate exposure and childhood type 1 insulin-dependent diabetes mellitus. The present ecologic study describes a possible relation between the incidence of type 1 diabetes and nitrate levels in drinking water in The Netherlands, and evaluates whether the World...article 2000
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Eikelboom, D.H. (author), Instituut voor Milieuhygiëne en Gezondheidstechniek TNO (author)Approximately 1100 activated sludge samples, mostly derived from purification plants with bulking sludge, were investigated for the presence of filamentous organisms. Twenty six types were distinguished which are preliminarily classified into seven groups. The sheath forming Gram negative and Gram positive bacteria are classified into Groups I...article 1975
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de Vos, R.H. (author), ten Noever de Brauw, M.C. (author), Olthof, P.D.A. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Pentachloronitrobenzene (PCNB, also known as Quintozene, Terraclor) is used as a soil fungicide in greenhouses, mainly for the control of Rhizoctonia and Botrytis in lettuce. During an examination (by gas liquid chromatography) of a number of soil samples from greenhouses, not only a PCNB peak was found in the chromatograms, but also several...article 1974
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Centraal Laboratorium TNO (author), Hueck, H.J. (author)Attention is directed at the importance of cyclic processes in nature for the functioning of the environment. In this light, the biodegradability of materials and chemicals is of great importance. In particular, persistence of chemicals, like DDT, is a phenomenon that deserves serious study. The possible causes of persistence are discussed,...article 1973