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Bloem, B.R. (author), Roon, K.I. (author), Delleman, N.J. (author), van Dijk, J.G. (author), Roos, R.A.C. (author), TNO Preventie en Gezondheid (author)We studied the influence of dopaminergic medication on the duration of standing up, static posture and gait in five patients with parkinson's disease (Hoehn and Yahr stage 1.5 to 3) and four healthy controls, using an optoelectronic camera system. Duration of standing up was prolonged in patients, while static posture and gait were largely...article 1997
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Scherphof, G.L. (author), Velinova, M. (author), Kamps, J. (author), Donga, J. (author), van der Want, H. (author), Kuipers, F. (author), Havekes, L. (author), Daemen, T. (author), TNO Preventie en Gezondheid (author)The authors's recent work on matters pertinent to the in vivo processing of systemically administered liposomes is reviewed. particular emphasis is given to factors influencing blood clearance rates, hepatic and splenic uptake and intrahepatic as well as intrasplenic distribution. In addition to size, liposomal composition plays a crucial role...article 1997
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Langerak, Edwin (author), TNO Milieu, Energie en Procesinnovatie (author)The recycling of mass consumer products like TV-sets and computers is gaining attention in Europe. The presence of (precious) metals traditionally has been the driving force for the recycling of equipment. While the plastics in electronics usually have a high quality, the recovery of them is problematic. In this paper the results are presented...conference paper 1997
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Prins Maurits Laboratorium TNO (author), Bouma, R.H.B. (author), Nauta, W.J. (author), Arnauts, J.E.F. (author), van den Boomgaard, T. (author), Steuten, J.M. (author), Strathmann, H. (author)In the production of polyethylene foams by extrusion with alkanes as a blowing agent, significant changes in the dimensions of extruded products are encountered. The dimensional stability of a foam with a structure of closed cells is improved by blending the polymer with small amounts of a low molecular weight additive. It is believed that the...article 1997
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- van Bree, J.L.M.J. (author), Duvalois, W. (author), Somogy, P. (author), Prins Maurits Laboratorium TNO (author) conference paper 1996
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Maassen van den Brink, A. (author), Dekker, H. (author), TNO Fysisch en Elektronisch Laboratorium (author)A calculation of the Kapitza boundary resistance between harmonic solids has been noted previously (Little, Can. J. Phys. 37 (1959) 334; Leung and Young, Phys. Rev. B 36 (1987) 4973) to lead to apparently paradoxical results in the limit of identical solids: instead of vanishing, the resistance tends to a finite limit. We resolve this paradox by...article 1996
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Visser, M.J.T. (author), van Lennep, A.C.D. (author), van Bockel, J.H. (author), van Hinsbergh, V.W.M. (author), van der Keur, M. (author), Hermans, J. (author), Gaubius Instituut TNO (author)For in vitro evaluation of functional properties of endothelial cells seeded on synthetic vascular prostheses accurate and reproducible quantification of cells is mandatory. Comparison of these properties with those resulting from other studies requires correlation of the functional parameters to reliably counted cell numbers. The accuracy of...article 1996
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van Os, P.J.H.J. (author), Bult, A. (author), Koopal, C.G.J. (author), van Bennekom, W.P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Recently a glucose sensor has been developed, which is easily prepared, has a good stability and high glucose response, and is interference free for ascorbic acid. The sensor was made by galvanostatic polymerization of 0.3 M pyrrole in a HEPES buffer pH 7.0 with 200 U ml-1 glucose oxidase (GOx) using a current of 1 μA. In this study, bare and...article 1996
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Vink, M. (author), van der Poll, J.M. (author), TNO Voeding (author)The development of a multi-residue method for the determination of eight polar acidic herbicides (MCPA, MCPB, mecoprop, 2,4-D, dichlorprop, bentazone, dicamba and dikegulac) in surface water is described. The method involves an off-line solid-phase extraction (SPE) procedure prior to instrumental analysis. The herbicides are isolated on an SPE C...article 1996
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Stigter, E.C.A. (author), de Jong, G.A.H. (author), Jongejan, J.A. (author), Duine, J.A. (author), van der Lugt, J.P. (author), Somers, W.A.C. (author), TNO Voeding (author)A quinohemoprotein alcohol dehydrogenase (QH-EDH) from Comamonas testosteroni was immobilized on an electrode in a redox polymer network consisting of a polyvinylpyridine partially N-complexed with osmiumbis-(bipyridine)chloride. The enzyme effectively transfers electrons to the electrode via the polymer. An average maximum catalytic current of...article 1996
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van Ewijk, L.J. (author), TNO Fysisch en Elektronisch Laboratorium (author)At the Physics and Electronics Laboratory TNO much research is done in the field of computational electromagnetics (CEM). One of the tools in this field is the Finite Difference Time Domain method (FDTD), a method that has been implemented in a program in order to be able to compute electromagnetic scattering by complex objects. In this paper a...conference paper 1996
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Huizing, Albert G. (author), Bloemen, Axel A.F. (author)The new generation of air defence frigates has to be equipped with a high performance sensor suite to cope with the threat in future maritime scenarios. A multifunction radar (MFR) with a single rotating or multiple fixed phased array antennas is often the key element in this sensor suite because it can perform not only surveillance functions...conference paper 1996
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- TNO Fysisch en Elektronisch Laboratorium (author), Spiel, D.E. (author), de Leeuw, G. (author) article 1996
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Schoolderman, A.J. (author), Prins Maurits Laboratorium TNO (author)In the literature on EML research, a number of proposals have been made to suppress the negative influence of the velocity skin effect on the performance of solid armatures during electromagnetic launch. In this paper, the results of a study of two of these methods, i.e. the application of multi-fibre solid brush armatures and the use of...conference paper 1995
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Papp, Z. (author), Driessen, B.J.F. (author), Technisch Physische Dienst TNO - TH (author)The paper presents an adaptive nonlinear (state-) feedback control structure, where the nonlinearities are implemented as smooth fuzzy mappings defined as rule sets. The fine tuning and adaption of the controller is realized by an indirect adaptive scheme, which modifies the parameters of the fuzzy mapping. The performance index gradients are...conference paper 1995
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Punt, P.J. (author), Veldhuisen, G. (author), van den Hondel, C.A.M.J.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Although the application of filamentous fungi, such as Aspergillus niger for the production of extracellular proteins is well established for several decades, hardly any information is available about the molecular mechanisms of the process of protein secretion in these organisms. Two lines of research initiated towards a systematic analysis of...article 1994
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Bosma, A. (author), Seifert, W.F. (author), de Thiel van - Ruiter, G.C.F. (author), van Leeuwen, R.E.W. (author), Blauw, B. (author), Roholl, P. (author), Knook, D.L. (author), Brouwer, A. (author), Gaubius Laboratory TNO Preventie en Gezondheid Instituut voor verouderings- en vaatziekten onderzoek TNO (author)Rats were malnourished for 12 months with a highly inadequate fat-rich, calorie-sufficient but otherwise poly-deficient liquid diet composed of mashed potatoes with mayonnaise, comparable with the nutritional intake of many chronic alcoholics. When alcohol was incorporated into this diet, administered as whisky in drinking water available ad...article 1994
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TNO Fysisch en Elektronisch Laboratorium (author), Joppe, J.L. (author), Bekman, H.H.P.T. (author), de Krijger, A.J.T. (author), Lambeck, P.V. (author), Chalmers, J. (author), Holleman, J. (author), Ikkink, T. (author), van Kranenburg, H. (author), Zhou, M.J. (author)A general platform for integrated opto-electronic sensor systems on silicon is proposed. The system is based on a hybridly integrated semiconductor laser, ZnO optical waveguides and monolithic photodiodes and electronic circuiry.conference paper 1994
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Koopman, J. (author), Haverkate, F. (author), Grimbergen, J. (author), Lord, S.T. (author), Mosesson, M.W. (author), DiOrio, J.P. (author), Siebenlist, K.S. (author), Legrand, C. (author), Soria, J. (author), Soria, C. (author), Caen, J.P. (author), Instituut voor verouderings- en vaatziekten onderzoek TNO (author)The molecular defect in the abnormal fibrinogen Dusart (Paris V) that is associated with thrombophilia was determined by sequence analysis of genomic DNA that had been amplified using the polymerase chain reaction. The propositus was heterozygous for a single base change (C → T) in the Aα- chain gene, resulting in the amino acid substitution Aα...article 1993
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Spit, B.J. (author), Bretschneider, F. (author), Hendriksen, E.G.J. (author), Kuper, C.F. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)The distribution of nerve fibres in the mucosa of the nasal septum of the rat was investigated by means of transmission electron microscopy on transverse and tangential ultrathin sections. Near the basement membrane of respiratory and squamous epithelium, a rather dense network of unmyelinated nerve fibres occurs. Some fibres in the respiratory...article 1993