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Kastelein, R.A. (author), Helder-Hoek, L. (author), Cornelisse, S.A. (author), von Benda-Beckmann, A.M. (author), Lam, F.P.A. (author), de Jong, C.A.F. (author), Ketten, D.R. (author)Noise-induced temporary hearing threshold shift (TTS) was studied in a harbor porpoise exposed to impulsive sounds of scaled-down airguns while both stationary and free-swimming for up to 90 min. In a previous study, ∼4 dB TTS was elicited in this porpoise, but despite 8 dB higher single-shot and cumulative exposure levels (up to 199 dB re 1...article 2020
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Ghosh, M. (author), Miroux, A. (author), Werkhoven, R.J. (author), Bolt, P.J. (author), Kestens, L.A.I. (author)The increasing use of aluminium alloys in light weight structural applications is restricted mainly due to their lower room temperature formability compared to steels. Forming at higher temperature is seen as a promising solution to this problem. In the present investigation two Al-Mg-Si alloys (EN AW-6016 and EN AW-6061) were deep-drawn at room...article 2014
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TNO Human Factors (author), Buytaert, K.I. (author), Nooij, S.A.E. (author), Neyt, X. (author), Migeotte, P.F. (author), Vanspauwen, R. (author), van de Heyning, P.H. (author), Wuyts, F.L. (author)The utricle plays an important role in orientation with respect to gravity. The unilateral centrifugation test allows a side-by-side investigation of both utricles. During this test, the subject is rotated about an earth-vertical axis at high rotation speeds (e.g. 400°/s) and translated along an interaural axis to consecutively align the axis of...article 2010
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Zwart, J.J. (author), Richters, J.M. (author), Öry, F. (author), de Vries, J.I.P. (author), Bloemenkamp, K.W.M. (author), van Roosmalen, J. (author)Objective: To assess incidence of uterine rupture in scarred and unscarred uteri and its maternal and fetal complications in a nationwide design. Design: Population-based cohort study. Setting: All 98 maternity units in the Netherlands. Population: All women delivering in the Netherlands between August 2004 and August 2006 (n = 371 021). Methods...article 2009
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Vogel, I. (author), Verschuure, H. (author), van der Ploeg, C.P.B. (author), Brug, J. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)OBJECTIVE. The goal was to assess risky and protective listening behaviors of adolescent users of MP3 players and the association of these behaviors with demographic characteristics and frequency of use. METHODS. In 2007, 1687 adolescents (12-19 years of age) in 68 classes in 15 Dutch secondary schools were invited to complete questionnaires...article 2009
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Vogel, I. (author), Brug, J. (author), Hosli, E.J. (author), van der Ploeg, C.P.B. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)Objective: To explore adolescents' behaviors and opinions about exposure to loud music from MP3 players. Study design: We conducted a qualitative analysis of focus-group discussions with adolescents aged 12 to 18 years from 2 large secondary schools (1 urban and 1 rural) for pre-vocational and pre-university education. The semi-structured...article 2008
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Vogel, I. (author), Brug, J. (author), van der Ploeg, C.P.B. (author), Raat, H. (author), TNO Kwaliteit van Leven (author)Objectives: This descriptive summary of the literature provides an overview of the available studies (published before October 2006) on sociodemographic, psychosocial, and other correlates of risk and protective behaviors for hearing loss in young people aged 12 to 25 years. Methods: Publications were identified by a structured search in PubMed,...article 2007
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Daanen, H.A.M. (author), TNO Defensie en Veiligheid (author)Several publications indicate that the infrared tympanic temperature (IRTT) underestimates the core temperature of the body when the ear canal is long, curvy and narrow. In order to quantify these observations, a study was performed in 10 subjects. The IRTT was determined and compared to the oesophageal temperature (Tes), taken as the reference...article 2006
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Hueber-Becker, F. (author), Nohynek, G.J. (author), Meuling, W.J.A. (author), Benech-Kieffer, F. (author), Toutain, H. (author), TNO Voeding (author)We investigated the absorption of a commercial [14C]-PPD- containing oxidative dark-shade hair dye in human volunteers as well as in vitro using human or pig ear skin. The hair of eight male volunteers was cut to a standard length, dyed, washed, dried, clipped and collected. Hair, washing water, materials used in the study and a 24-h scalp wash...article 2004
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Crabtree, B. (author), Abel, S. (author), Dancer, A.L. (author), Buck, K. (author), Wessling, T. (author), Steeneker, H.J.M. (author), Verhave, J. (author), James, S.H. (author), Rood, G. (author), McKinley, R. (author)Hearing protection with standard passive earmuffs is for many military applications insufficient. Low frequency noises (diesel engines, helicopter rotor) require increased attenuation. Active Noise Reduction (ANR) is specifically suited for reduction at low frequencies. Assessment of ANR for military applications is an important topic as the...report 2004
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van Wijngaarden, S.J. (author), Rots, G. (author), TNO Technische Menskunde (author)Background: Aircrews are often exposed to high ambient sound levels, especially in military aviation. Since long-term exposure to such noise may cause hearing damage, selection of adequate hearing protective devices is crucial. Such devices also affect speech intelligibility. When speech intelligibility and hearing protection lead to conflicting...article 2001
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van Wijngaarden, S.J. (author), Agterhuis, E. (author), Steeneken, H.J.M. (author), TNO Human Factors (author)A laboratory model of the wireless "Communications EarPlug" (w-CEP) was developed. Standard communication earplugs (using wires) are known to offer relatively good intelligibility of intercom speech at high ambient noise levels. The intercom sound is produced by means of a commercially available miniature transducer, integrated in the earplug....article 2000
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van de Sandt, J.J.M. (author), Meuling, W.J.A. (author), Elliott, G.R. (author), Cnubben, N.H.P. (author), Hakkert, B.C. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)In vitro and in vivo skin absorption of the pesticide propoxur (2-isopropoxyphenyl N-methyl carbamate, commercially Baygon(TM) and Unden(TM); log Po/w 1.56, MW 209.2) was investigated. In vivo studies were performed in rats and human volunteers, applying the test compound to the dorsal skin and the volar aspect of the forearm, respectively. In...article 2000
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Cappaert, N.L.M. (author), Klis, S.F.L. (author), Muijser, H. (author), de Groot, J.C.M.J. (author), Kulig, B.M. (author), Smoorenburg, G.F. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)Exposure to organic solvents has been shown to be ototoxic in animals and there is evidence that these solvents can induce hearing loss in humans. In this study, the effects of inhalation of the possibly ototoxic solvent ethyl benzene on the cochlear function and morphology were evaluated using three complementary techniques: (1) reflex...article 1999
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Arts, J.H.E. (author), Dröge, S.C.M. (author), Bloksma, N. (author), Kuper, C.F. (author), Instituut CIVO-Toxicologie en Voeding TNO (author)Five rat strains were compared for their performance in the local lymph node assay (LLNA) a promising test system for the identification of the skin-sensitizing potential of chemicals in the mouse. The contact sensitizer 2,4-dinitrochlorobenzene (DNCB) and the contact and respiratory sensitizer trimellitic anhydride (TMA) were used as model...article 1996
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de Lange, J. (author), van Eck, P. (author), Elliott, G.R. (author), de Kort, W.L.A.M. (author), Wolthuis, O.L. (author), Medisch Biologisch Laboratorium TNO (author)To overcome most of the disadvantages of current models to investigate percutaneous penetration of drugs or toxic substances, a model is proposed here based on the isolated pig ear, which is obtained at the slaughterhouse, and perfused with oxygenated blood from the same pig. To determine the viability of the preparations, we measured glucose...article 1992
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- Instituut voor Zintuigfysiologie TNO (author), Smith, P. (author) book 1988
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Radiobiologisch Instituut TNO (author), Sindram, P.J. (author), Snow, G.B. (author), van Putten, L.M. (author)Chemicals/CAS: folinate calcium, 1492-18-8, 51057-63-7; folinic acid, 58-05-9, 68538-85-2; methotrexate, 15475-56-6, 59-05-2, 7413-34-5; Leucovorin, 58-05-9; Methotrexate, 59-05-2article 1974
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- Instituut voor Zintuigfysiologie TNO (author) book 1966