Searched for: subject:"EMS%5C+%5C-%5C+Environmental%5C+Modelling%2C%5C+Sensing%5C+%26%5C+Analysis"
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Dankers, A.C.A. (author), Kuper, C.F. (author), Boumeester, A.J. (author), Fabriek, B.O. (author), Kooter, I.M. (author), Gröllers-Mulderij, M. (author), Tromp, P. (author), Nelissen, I. (author), Zondervan-Van Den Beuken, E.K. (author), Vandebriel, R.J. (author)
Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled metal oxide NPs may generate inflammation. The aim of this study was to investigate the proinflammatory potential of six metal oxide NPs (CeO2, Mn2O3, CuO, ZnO, Co3O4 and WO3; 27–108 μg ml−1) using human primary 3-dimensional airway epithelium (MucilAir™)...
article 2018
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Zarcone, M.C. (author), Duistermaat, E. (author), Alblas, M.J. (author), van Schadewijk, A. (author), Ninaber, D.K. (author), Clarijs, V. (author), Moerman, M.M. (author), Vaessen, D. (author), Hiemstra, P.S. (author), Kooter, I.M. (author)
Harmful effects of diesel emissions can be investigated via exposures of human epithelial cells, but most of previous studies have largely focused on the use of diesel particles or emission sources that are poorly representative of engines used in current traffic. We studied the cellular response of primary bronchial epithelial cells (PBECs) at...
article 2018
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Hiemstra, P.S. (author), Grootaers, G.G. (author), van der Does, A.M. (author), Krul, C.A.M. (author), Kooter, I.M. (author)
The epithelium that covers the conducting airways and alveoli is a primary target for inhaled toxic substances, and therefore a focus in inhalation toxicology. The increasing concern about the use of animal models has stimulated the development of in vitro cell culture models for analysis of the biological effects of inhaled toxicants. However,...
article 2018
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LaCroix, G. (author), Koch, W. (author), Ritter, D. (author), Gutleb, A.C. (author), Larsen, S.T. (author), Loret, T. (author), Zanetti, F. (author), Constant, S. (author), Chortarea, S. (author), Rothen-Rutishauser, B. (author), Hiemstra, P.S. (author), Frejafan, E. (author), Hubert, P. (author), Gribaldo, L. (author), Kearns, P. (author), Aublant, J.M. (author), Diabaté, S. (author), Weiss, C. (author), de Groot, A. (author), Kooter, I.M. (author)
In vitro air–liquid interface (ALI) cell culture models can potentially be used to assess inhalation toxicology endpoints and are usually considered, in terms of relevancy, between classic (i.e., submerged) in vitro models and animal-based models. In some situations that need to be clearly defined, ALI methods may represent a complement or an...
article 2018
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Markus, A.A. (author), Krystek, P. (author), Tromp, P.C. (author), Parsons, J.R. (author), Roex, E.W.M. (author), de Voogt, P. (author), Laane, R.W.P.M. (author)
We investigated the occurrence of metal-based nanoparticles in a natural system, the river Dommel in the Netherlands. The river itself is well-studied as far as hydrology and water quality is concerned, easily accessible and contains one major wastewater treatment plant discharging onto this river. We sampled water from various locations along...
article 2018
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de Kluizenaar, Y. (author), Kuijpers, E. (author), Eekhout, I. (author), Voogt, M. (author), Vermeulen, R.C.H. (author), Hoek, G. (author), Sterkenburg, R.P. (author), Pierik, F.H. (author), Duyzer, J.H. (author), Meijer, E.W. (author), Pronk, A. (author)
Particulate matter exposure may cause adverse health effects. Although ultrafine particulate matter (UFP) is hypothesised to be particularly health relevant, the number of studies into personal UFP exposure is limited. Aim To increase insight where and when most UFP exposure occurs, in terms of exposure levels and peaks in microenvironments,...
article 2017
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Tromp, P.C. (author), Kuijpers, E. (author), Bekker, C. (author), Godderis, L. (author), Lan, Q. (author), Jedynska, A.D. (author), Vermeulen, R. (author), Pronk, A. (author)
To date there is no consensus about the most appropriate analytical method for measuring carbon nanotubes (CNTs), hampering the assessment and limiting the comparison of data. The goal of this study is to develop an approach for the assessment of the level and nature of inhalable multi-wall CNTs (MWCNTs) in an actual workplace setting by...
article 2017
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Downward, G.S. (author), Hu, W. (author), Rothman, N. (author), Reiss, B. (author), Tromp, P. (author), Wu, G. (author), Wei, F. (author), Xu, J. (author), Seow, W.J. (author), Chapman, R.S. (author), Lan, Q. (author), Vermeulen, R. (author)
Exposure to crystalline silica (quartz) has been implicated as a potential cause of the high lung cancer rates in the neighbouring counties of Xuanwei and Fuyuan, China, where the domestic combustion of locally sourced “smoky” coal (a bituminous coal) is responsible for some of the highest lung cancer rates in the nation, irrespective of gender...
article 2017
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Jedynska, A. (author), Hoek, G. (author), Wang, M. (author), Yang, A. (author), Eeftens, M. (author), Cyrys, J. (author), Keuken, M. (author), Ampe, C. (author), Beelen, R. (author), Cesaroni, G. (author), Forastiere, F. (author), Cirach, M. (author), de Hoogh, K. (author), de Nazelle, A. (author), Nystad, W. (author), Akhlaghi, H.M. (author), Declercq, C. (author), Stempfelet, M. (author), Eriksen, K.T. (author), Dimakopoulou, K. (author), Lanki, T. (author), Meliefste, K. (author), Nieuwenhuijsen, M. (author), Yli-Tuomi, T. (author), Raaschou-Nielsen, O. (author), Janssen, N.A.H. (author), Brunekreef, B. (author), Kooter, I.M. (author)
Oxidative potential (OP) has been suggested as a health-relevant measure of air pollution. Little information is available about OP spatial variation and the possibility to model its spatial variability. Our aim was to measure the spatial variation of OP within and between 10 European study areas. The second aim was to develop land use...
article 2017
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Fraters, D. (author), Boom, G.J.F.L. (author), Boumans, L.J.M. (author), de Weerd, H. (author), Wolters, M. (author)
The solute concentration in the subsoil beneath the root zone is an important parameter for leaching assessment. Drainage centrifugation is considered a simple and straightforward method of determining soil solution chemistry. Although several studies have been carried out to determine whether this method is robust, hardly any results are...
article 2017
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Gallocchio, F. (author), Biancotto, G. (author), Cibin, V. (author), Losasso, C. (author), Belluco, S. (author), Peters, R. (author), van Bemmel, G. (author), Cascio, C. (author), Weigel, S. (author), Tromp, P. (author), Gobbo, F. (author), Catania, S. (author), Ricci, A. (author)
Silver nanoparticles (AgNPs) are of interest due to their antimicrobial activity and are seen as potential candidates to replace antibiotics in animal husbandry. A few studies have focused on this new application, but they lack any considerations about residual accumulation of AgNPs in edible animal tissues and animal products. In this research,...
article 2017
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Smedes, F. (author), Rusina, T.P. (author), Beeltje, H. (author), Mayer, P. (author)
Polymers are increasingly used for passive sampling of neutral hydrophobic organic substances (HOC) in environmental media including water, air, soil, sediment and even biological tissue. The equilibrium concentration of HOC in the polymer can be measured and then converted into equilibrium concentrations in other (defined) media, which however...
article 2017
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Kooter, I.M. (author), Grollers-Mulderij, M. (author), Duistermaat, E. (author), Kuper, C.F. (author)
Mucilair 3D bronchial airway models, cultured at an air-liquid interface, were exposed to aerosols of copper oxide (CuO) nanoparticles in Vitrocell air exposure modules. Four cell donors, four exposure modules and four exposure concentrations were varied within four different exposure sessions using a statistical experimental design called a...
article 2017
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Zarcone, M.C. (author), van Schadewijk, A. (author), Duistermaat, E. (author), Hiemstra, P.S. (author), Kooter, I.M. (author)
Background: Exacerbations constitute a major cause of morbidity and mortality in patients suffering from chronic obstructive pulmonary disease (COPD). Both bacterial infections, such as those with non-typeable Haemophilus influenzae (NTHi), and exposures to diesel engine emissions are known to contribute to exacerbations in COPD patients....
article 2017
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Okokon, E.O. (author), Yli-Tuomi, T. (author), Turunen, A.W. (author), Taimisto, P. (author), Pennanen, A. (author), Vouitsis, I. (author), Samaras, Z. (author), Voogt, M. (author), Keuken, M. (author), Lanki, T. (author)
Background: In order to curb traffic-related air pollution and its impact on the physical environment, contemporary city commuters are encouraged to shift from private car use to active or public transport modes. However, personal exposures to particulate matter (PM), black carbon and noise during commuting may be substantial. Therefore, studies...
article 2017
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Helsper, J.P.F.G. (author), Peters, R.J.B. (author), van Bemmel, M.E.M. (author), Rivera, Z.E.H. (author), Wagner, S. (author), von der Kammer, F. (author), Tromp, P.C. (author), Hofmann, T. (author), Weigel, S. (author)
Seven commercial titanium dioxide pigments and two other well-defined TiO2 materials (TiMs) were physicochemically characterised using asymmetric flow field flow fractionation (aF4) for separation, various techniques to determine size distribution and inductively coupled plasma mass spectrometry (ICPMS) for chemical characterization. The aF4...
article 2016
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Tromp, P.C. (author)
Inleiding en doelstelling Sinds 1978 is asbestbeleid ontwikkeld en uitgevoerd, gericht op het terugdringen van het voorkomen van asbest in enigerlei vorm in het binnen- en buitenmilieu. Het is te verwachten dat vooral het verbod op asbesthoudende remvoeringen en het sluiten van de asbest verwerkende industrie tot een aanzienlijke reductie van de...
report 2016
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Beccaceci, S. (author), Brown, R.J.C. (author), Butterfield, D.M. (author), Harris, P.M. (author), Otjes, R.P. (author), van Hoek, C. (author), Makkonen, U. (author), Catrambone, M. (author), Patier, R.F. (author), Houtzager, M.M.G. (author), Putaud, J.P. (author)
European Committee for Standardisation (CEN) Technical Committee 264 ‘Air Quality’ has recently produced a standard method for the measurements of anions and cations in PM2.5 within its Working Group 34 in response to the requirements of European Directive 2008/50/EC. It is expected that this method will be used in future by all Member States...
article 2016
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Zarcone, M.C. (author), Duistermaat, E. (author), van Schadewijk, A. (author), Jedynksa, A.D. (author), Hiemstra, P.S. (author), Kooter, I.M. (author)
Cellular response of mucociliary differentiated primary bronchial epithelial cells to diesel exhaust. Am J Physiol Lung Cell Mol Physiol 311: L111–L123, 2016. First published May 17, 2016; doi:10.1152/ajplung.00064.2016.—Diesel emissions are the main source of air pollution in urban areas, and diesel exposure is linked with substantial adverse...
article 2016
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Al-Moniee, M.A. (author), Koopal, C. (author), Akmal, N. (author), van Veen, J.J.F. (author), Zhu, X. (author), Sanders, P.F. (author), Al-Abeedi, F.N. (author), Amer, A.M. (author)
Biocides are oilfield chemicals that are widely used to control bacterial activity
article 2016
Searched for: subject:"EMS%5C+%5C-%5C+Environmental%5C+Modelling%2C%5C+Sensing%5C+%26%5C+Analysis"
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