Searched for: subject:"ELSS%5C+%5C-%5C+Earth%2C%5C+Life%5C+and%5C+Social%5C+Sciences"
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Schlunk, F. (author), Fisher, P. (author), Princen, H.M.G. (author), Rex, A. (author), Prinz, V. (author), Foddis, M. (author), Lütjohann, D. (author), Laufs, U. (author), Endres, M. (author)
Monoclonal anti-proprotein convertase subtilisin/kexin type 9 (PSCK9) neutralizing antibodies effectively lower plasma cholesterol levels and decrease cardiovascular events but also raised some concern that cognitive function could worsen as a side effect. Here, we performed experiments in mice to characterize the effect of anti-PCSK9 antibodies...
article 2021
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Goemans, B.F. (author), Noort, S. (author), Blink, M. (author), Wang, Y.D. (author), Peters, S.T.C.J. (author), van Wouwe, J.P. (author), Kaspers, G. (author), de Haas, V. (author), Kollen, W.J. (author), van der Velden, V.H.J. (author), Gruber, T.A. (author), Zwaan, C.M. (author)
The aim of this study was to define a population-based frequency of TAM in DS newborns. The Dutch Pediatric Surveillance Unit (DPSU) registers newborns with DS and TAM screening was added to this registration from Jan 1, 2008, until Jan 1, 2013 (Erasmus MC MEC-2007-168, Netherlands Trial Register NL1587). Based on the live birth prevalence of DS...
article 2021
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Hooftman, W.E. (author), van Dam, L.M.C. (author)
De COVID-19 pandemie heeft voor een forse toename van tijd- en plaatsonafhankelijk werken gezorgd. Maar dit proces was al eerder in gang gezet. Uit de Arbobalans 2020 blijkt dat het aandeel werknemers dat tijden plaatsonafhankelijk kan werken tussen 2014 en 2019 is toegenomen. Vakmedianet
article 2021
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Bonnemaijer-Kerckhoffs, D.J.A. (author), Wins, S.I. (author), van Dommelen, P. (author), Verkerk, P.H. (author)
Inleiding: In de Jeugdgezondheidszorg (JGZ)-richtlijn Autismespectrumstoornissen (ASS) zijn op basis van expert-opinion zeven ontwikkelingskenmerken uit het Van Wiechen-onderzoek aangeduid als alarmsignalen voor ASS. Dit onderzoek had als doel de criteriumvaliditeit van deze kenmerken vast te stellen. Methode: In de periode 2009–2013 werden de...
article 2021
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Wetselaar, P. (author), Vermaire, E.J.H. (author), Lobbezoo, F. (author), Schuller, A.A. (author)
Objectives: This study aimed to assess the prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population. Materials and methods: As part of a large epidemiologic survey on oral health of the general Dutch adolescent population in 2017, a total of 920 subjects were asked about their bruxism behaviour during daytime and during...
article 2021
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Rijnders, M. (author), Jans, S (author), Groesen, K. (author)
Reduced antenatal care services and an acute halt to Centeringbased antenatal group care were one of the results of the COVID-19 lockdown in the Netherlands. The pandemic and the subsequent reduction in antenatal services gave rise to anxiety and stress in pregnant women, increasing the need for group antenatal care more than ever. Throughout...
article 2021
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Vooijs, M. (author), van Kesteren, N. (author), Hazelzet, A.M. (author), Otten, W. (author)
Background: Work participation is an important determinant of public health; being unemployed leads to a decrease in an individual's health. In the Netherlands, people with a work disability can apply for disability benefits, in which people also receive support to return to work (RTW). A method, currently used in the medical sector, that can...
article 2021
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Hooftman, W.E. (author), van Dam, L.M.C. (author)
De ervaren fysieke zwaarte van het werk is toegenomen tijdens de covid-19 pandemie. In november 2020 gaf ruim 18 procent van de werknemers die tijdens de Covid-19 pandemie op locatie bleven werken aan dat het werk door de maatregelen lichamelijk zwaarder voelt dan normaal. Werknemers die volledig op locatie werken (21%) vinden relatief vaker dat...
article 2021
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Gopaul, V.S. (author), Pieterman, E.J. (author), Princen, H.M.G. (author), Bergenholm, L. (author), Lundborg, E. (author), Cavallin, A. (author), Johansson, M.J. (author), Hawthorne, G. (author), Björkbom, A. (author), Hammarberg, M. (author), Li, X. (author), Jarke, A. (author), Bright, J. (author), Svensson, L. (author), Jansson-Löfmark, R. (author), Abrahamsson, B. (author), Agrawal, R. (author), 1 Hurt-Camejo, E. (author)
We investigated the effects of mineral oil on statin pharmacokinetics and inflammatory markers in animal models. A new synthesis strategy produced regioisomers that facilitated the characterization of the main metabolite (M1) of atorvastatin, a lipophilic statin, in C57BL/6NCrl mice. The chemical structure of M1 in mice was confirmed as ortho...
article 2021
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van Gemert, Y. (author), Kozijn, A.E. (author), Pouwer, M.G. (author), Kruisbergen, N.N.L. (author), van den Bosch, M.H.J. (author), Blom, A.B. (author), Pieterman, E.J. (author), Weinans, H. (author), Stoop, R. (author), Princen, H.M.G. (author), van Lent, P.L.E.M. (author)
Objective: High systemic cholesterol levels have been associated with osteoarthritis (OA) development. Therefore, cholesterol lowering by statins has been suggested as a potential treatment for OA. We investigated whether therapeutic high-intensive cholesterol-lowering attenuated OA development in dyslipidemic APOE*3Leiden.CETP mice. Methods:...
article 2021
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van der Ploeg, C.P.B. (author), Grevinga, M. (author), Eekhout, I. (author), Vlasblom, E. (author), Lanting, C.I. (author), van Minderhout, H.M. (author), Dijk-van der Poel, J. (author), van den Akker-van Marle, M.E. (author), Verkerk, P.H. (author)
Background: Little is known about costs and effects of vision screening strategies to detect amblyopia. Aim of this study was to compare costs and effects of conventional (optotype) vision screening, photoscreening or a combination in children aged 3-6 years. Methods: Population-based, cross-sectional study in preventive child health care in The...
article 2021
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Naafs, J.C. (author), Marchal, J.P. (author), Verkerk, P.H. (author), Fliers, E. (author), van Trotsenburg, A.S.P. (author), Zwaveling-Soonawala, N. (author)
Context. Central congenital hypothyroidism (CH) requires lifelong medical treatment. The majority of children with central CH have multiple pituitary hormone deficiencies (MPHD), but in some cases central CH is isolated. Most pituitary hormone deficiencies are associated with impaired health-related quality of life (HRQoL). However, studies on...
article 2021
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van der Ploeg, C.P.B. (author), Grevinga, M. (author), Eekhout, I. (author), Vlasblom, E. (author), Lanting, C.I. (author), van Minderhout, H.M. (author), Dijk-van der Poel, J. (author), van den Akker-van Marle, M.E. (author), Verkerk, P.H. (author)
Comment on the article: Costs and effects of conventional vision screening and photoscreening in the Dutch preventive child health care system. We thank professor Simonsz for his comments, since it gives us the opportunity to clarify some of our findings. Indeed, with the price for the photoscreening device of €2.29 per child as calculated in...
article 2021
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Hooftman, W.E. (author), van Dam, L.M.C. (author)
Het aandeel werknemers met burnoutklachten is tussen 2014 en 2018 toegenomen van 14 naar 17 procent, om daarna te stabiliseren. Ook tijdens de covid-19 pandemie blijft het aandeel werknemers met burn-outklachten redelijk stabiel. Vakmedianet
article 2021
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van der Burg, L.R.A. (author), van Kuijk, S.M.J. (author), ter Wee, M.M. (author), Heymans, M.W. (author), de Rijk, A.E. (author), Geuskens, G.A. (author), Ottenheijm, R.P.G. (author), Dinant, G.J. (author), Boonen, A. (author)
Background: Societal expenditures on work-disability benefits is high in most Western countries. As a precursor of long-term work restrictions, long-term sickness absence (LTSA) is under continuous attention of policy makers. Different healthcare professionals can play a role in identification of persons at risk of LTSA but are not well trained....
article 2020
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de Mooij, B. (author), Fekkes, M. (author), Scholte, R.H.J. (author), Overbeek, G. (author)
Social skills training (SST) programs for nonclinical children and adolescents are known to have positive effects on social skills, but it remains unclear how distinct training components are related to program effects. This multilevel meta-analysis examines how psychoeducation (i.e., exercises aimed at the transfer of knowledge), psychophysical...
article 2020
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Hooftman, W.E. (author), van Dam, L.M.C. (author)
Werkgevers in Nederland zijn al sinds 1994 verplicht om een Rl&E met plan van aanpak te maken om de risico's in hun bedrijf in kaart te brengen. Vakmedianet
article 2020
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van der Pal, S.M. (author), Steinhoff, M. (author), Grevinga, M. (author), Wolke, D. (author), Verrips, G.H.W. (author)
This systematic review was performed in the context of EU‐project RECAP (www.recap-preterm.eu) and thus with funding from the European Commission; Horizon 2020; Grant Number: 733280. Aim. To establish differences in health‐related quality of life (HRQoL) in adults born term and those born very preterm (VPT) and/or with a very low birth weight ...
article 2020
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Hooftman, W.E. (author), van Dam, L.M.C. (author)
Circa 16 procent van de werknemers in Nederland heeft een enkele keer tot zeer vaak te maken met ongewenste omgangsvormen van leidinggevenden of collega’s. Daarnaast heeft ook nog bijna 6 procent van de werknemers te maken met discriminatie op de werkvloer. Circa 16 procent van de werknemers in Nederland heeft een enkele keer tot zeer vaak te...
article 2020
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Vink, R. (author), de Wolff, M. (author), Broerse, A. (author), Kamphuis, M. (author)
Ook de richtlijn Kindermishandeling is geactualiseerd. Sinds de eerste publicatie van de richtlijn in 2016 is er veel veranderd in de aanpak van kindermishandeling. De richtlijn is aangevuld met nieuwe onderzoeksresultaten en nieuwe interventies. Verder hebben ervaringen met het gebruik van de richtlijn geleid tot verbeteringen. Deze richtlijn...
report 2020
Searched for: subject:"ELSS%5C+%5C-%5C+Earth%2C%5C+Life%5C+and%5C+Social%5C+Sciences"
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