Searched for: subject%3A%22Development%22
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Kuijpers, E. (author), Pronk, A. (author), Koivisto, A.J. (author), Jensen, K.A. (author), Vermeulen, R. (author), Fransman, W. (author)
Introduction. Knowledge on the exposure characteristics, including release of nanomaterials, is especially needed in the later stages of nano-enabled products’ life cycles to perform better occupational risk assessments. The objective of this study was to assess the concentrations during sawing and drilling in car bumpers containing multi-walled...
article 2019
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Diepeveen, F.B. (author)
Specific language impairment (SLI), or developmental language disorder, is the most prevalent development disorder in childhood. However, most children with SLI are detected late. Predictive properties of language milestones and risk factors for having SLI later in life were investigated in a nested case-control study. The outcomes showed that...
doctoral thesis 2019
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Schinkel, J. (author), Heerderik, D. (author), Helsloot, I. (author), Kraaijenbrink, S. (author), Vis, J. (author)
In veel situaties is momenteel onduidelijk wat de blootstelling aan asbest (door inhalatie) werkelijk is, en daarmee wat de bijbehorende gezondheidsrisico’s zijn. Hierdoor is het dus veelal niet mogelijk om vast te stellen wat proportionele veiligheidsmaatregelen zijn.
report 2019
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Ediati, A. (author), Verrips, G.H.W. (author), Juniarto, A.Z. (author), Faradz, S.M.H. (author), Drop, S.L.S. (author), Dessens, A.B. (author)
Background:Patients with a disorder of sex development (DSD) are born with atypical genitals or may develop atypical genitals and atypical body appearance, if left untreated. Health related quality of life (HRQoL) was assessed in Indonesian patients to whom diagnostic procedures and medical intervention had been delayed. Method: Comparison of...
article 2019
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Vlasblom, E. (author), Boere-Boonekamp, M.M. (author), Hafkamp-de Groen, E. (author), Dusseldorf, E. (author), van Dommelen, P. (author), Verkerk, P.H. (author)
Developmental milestones are commonly used in child health care, although from many milestones the predictive validity has not been adequately assessed. We aimed to determine the predictive validity of 75 developmental milestones for detecting limited intellectual functioning that can be obtained before the age of 4 years. We performed a case...
article 2019
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Semenzina, E. (author), Subramanian, V. (author), Pizzo, L. (author), Zabeo, A. (author), Fransman, W. (author), Oksel, C. (author), Hristozov, D. (author), Marcomini, A. (author)
The widespread use of engineered nanomaterials (ENMs) in consumer products and the overwhelming uncertainties in their ecological and human health risks have raised concerns regarding their safety among industries and regulators. There has been an ongoing debate over the past few decades on ways to overcome the challenges in assessing and...
article 2019
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QuSoft, QT/e, NWO, het Lorentz Instituut, AMS-IX, StartupDelta en Microsoft, m.m.v. EZK TNO, QuTech, (author)
report 2019
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Weber, A.M. (author), Rubio-Codina, M. (author), Walker, S.P. (author), van Buuren, S. (author), Eekhout, I. (author), Grantham-Mcgregor, S.M. (author), Araujo, M.C. (author), Chang, S.M. (author), Fernald, L.C.H. (author), Hamadani, J.D. (author), Hanlon, C. (author), Karam, S.M. (author), Lozoff, B. (author), Ratsifandrihamanana, L. (author), Richter, L. (author), Black, M.M. (author)
Introduction Early childhood development can be described by an underlying latent construct. Global comparisons of children's development are hindered by the lack of a validated metric that is comparable across cultures and contexts, especially for children under age 3 years. We constructed and validated a new metric, the Developmental Score (D...
article 2019
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Huijs, J.J.J.M. (author), Houtman, I.L.D. (author), Blonk, R.W.B. (author)
Background. The aim of this study is to develop a new measure for the concept of mental retirement and test the construct validity of the measure. Employees who are ‘mentally retired’ are present at their work physically, but have already said their goodbyes mentally. Mental retirement has a three-factor structure: developmental proactivity,...
article 2019
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Derks, M.J.W. (author), Romijn, H. (author)
Rural off-grid electrification systems powered by renewable energy have become popular in the Global South. Unfortunately, many microgrids have experienced trouble during their first years of operation, leading to premature system deterioration. In this paper we trace these problems to institutional issues associated with goal displacement in...
article 2019
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Nagele, T. (author), Broenink, T. (author), Hooman, J. (author), Broenink, J. (author)
The multi-disciplinary nature of the design of cyber-physical systems makes it hard to gain insight in the system behaviour early in the design process. Our aim is to allow the designers to analyse the integration of system components as well as the behaviour of the complete system in an early stage. This is achieved by creating abstract...
conference paper 2019
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Savic, N. (author), Gasic, B. (author), Schinkel, J. (author), Vernez, D. (author)
The Advanced REACH Tool (ART) is the most sophisticated tool used for evaluating exposure levels under the European Union's Registration, Evaluation, Authorisation and restriction of CHemicals (REACH) regulations. ART provides estimates at different percentiles of exposure and within different confidence intervals (CIs). However, its performance...
article 2018
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Dams, D. (author), Mooij, A. (author), Kramer, P. (author), Radulescu, A. (author), Vanhara, J. (author)
The high-tech industry is faced with ever growing amounts of software to be maintained and extended. To keep the associated costs under control, there is a demand for more human overview and for large-scale code restructurings. Language technology such as parsing can assist in this, but classical restructuring tools are typically not flexible...
conference paper 2018
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Nooren, P.A. (author), van Adrichem, N.L.M. (author), D'Acunto, L. (author)
conference paper 2018
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Veldhuis, G.A. (author), de Reus, N.M. (author), Keijser, B.M.J. (author)
Modern warfighting is not only conducted on the physical battlefield but also engages actors in the information and human landscapes. Across these landscapes many types of actors characterize a comprehensive environment. A commander and staff follow the operations planning process to translate a desired end-state to tactical effects and...
article 2018
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Schuts, M. (author), Hooman, J.J.M. (author), Kurtev, I. (author), Swagerman, D.J. (author)
Cyber-physical systems consist of many hardware and software components. Over the life-cycle of these systems, components are replaced or updated. To avoid integration problems, good interface descriptions are crucial for component-based development of these systems. For new components, a Domain Specific Language called Component Modeling...
conference paper 2018
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Dankers, A.C.A. (author), Kuper, C.F. (author), Boumeester, A.J. (author), Fabriek, B.O. (author), Kooter, I.M. (author), Gröllers-Mulderij, M. (author), Tromp, P. (author), Nelissen, I. (author), Zondervan-Van Den Beuken, E.K. (author), Vandebriel, R.J. (author)
Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled metal oxide NPs may generate inflammation. The aim of this study was to investigate the proinflammatory potential of six metal oxide NPs (CeO2, Mn2O3, CuO, ZnO, Co3O4 and WO3; 27–108 μg ml−1) using human primary 3-dimensional airway epithelium (MucilAir™)...
article 2018
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Schuts, M. (author), Hooman, J. (author), Tielemans, P. (author)
Software departments of companies that exist for several decades often have to deal with legacy models. Important business assets have been modelled with tools that are no longer preferred within the company. Manually remodelling these models with a new tool would be too costly. In this paper, we describe an approach to migrate from Rhapsody...
conference paper 2018
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Koivisto, A.J. (author), Pizzol, L. (author), Basei, G. (author), Zabeo, A. (author), Mackevica, A. (author), Hansen, S.F. (author), Gosens, I. (author), Cassess, F.R. (author), de Jong, W. (author), Koivisto, A.J. (author), Neubauer, N. (author), Sanchaz, J.A. (author), Semenzin, E. (author), Subramanian, V. (author), Fransman, W. (author), Jensen, K.A. (author), Wohlleben, W. (author), Stone, V. (author), Marcomini, A. (author)
The use of nano-scale copper oxide (CuO) and basic copper carbonate (Cu2(OH)2CO3) in both ionic and micronized wood preservatives has raised concerns about the potential of these substances to cause adverse humans health effects. To address these concerns, we performed quantitative (probabilistic) human health risk assessment (HHRA) along the...
article 2018
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Rodríguez-Espíndola, O. (author), Albores, P. (author), Brewster, C. (author)
Purpose: Decision-making structures are commonly associated with the logistics challenges experienced during disaster operations. However, the alignment between the operational level and the decision-making structure is commonly overlooked. The purpose of this paper is to provide an analysis of the fit of both levels and its impact on...
article 2018
Searched for: subject%3A%22Development%22
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