Searched for: subject:"Determinants"
(41 - 60 of 142)

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Fleuren, M.A.H. (author), Wiefferink, K. (author), Paulussen, T.G.W.M. (author)
In 2006 we published an article on 50 determinants of innovations in health care organizations. A brief description of all determinants and their influence was given. Implementation researchers and implementation consultants or advisors have asked us repeatedly to publish a full description of the determinants. The full description of the...
article 2010
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Moon, B.-U. (author), Koster, S. (author), Wientjes, K.J.C. (author), Kwapiszewski, R.M. (author), Schoonen, A.J.M. (author), Westerink, B.H.C. (author), Verpoorte, E. (author), TNO Kwaliteit van Leven (author)
The development of continuous glucose monitoring systems is a major trend in diabetes-related research. Small, easy-to-wear systems which are robust enough to function over many days without maintenance are the goal. We present a new sensing system for continuous glucose monitoring based on a microreactor incorporating chaotic mixing channels....
article 2010
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Nijenhuis, J.R. (author), Hamelinck, R.F.M.M. (author), Braam, B.C. (author), Cayrel, M. (author), TNO Industrie en Techniek (author)
The largest optical telescope in the world will be the E-ELT. Its primary mirror will be 42m in diameter. This mirror will consist of 984 hexagonal segments that are all individually supported. Each mirror will be controlled in six DOF while local shaping of the segments is provided by so called warping harnesses. These will correct for focus,...
conference paper 2010
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van Nuland, H.J.C. (author), Dusseldorp, E. (author), Martens, R.L. (author), Boekaerts, M. (author), TNO Kwaliteit van Leven (author)
Different theoretical viewpoints on motivation make it hard to decide which model has the best potential to provide valid predictions on classroom performance. This study was designed to explore motivation constructs derived from different motivation perspectives that predict performance on a novel task best. Motivation constructs from self...
article 2010
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Kruiver, P.P. (author), Westerhoff, R.S. (author), Noorlandt, R.P. (author), Hoekstra, N.N. (author), Woelders, H. (author), van Vossen, W.J. (author), TNO Bouw en Ondergrond (author)
Geophysical investigations were carried out on two modern landfill sites in the Netherlands. The objective of the geo-electrical and EM31 measurements was to reveal the effect of recirculation of leachate on homogenising moisture content in the waste to stimulate the process of attenuation. At Vlagheide, geo-electrical and EM31 measurements were...
conference paper 2009
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End, C. (author), Bikker, F.J. (author), Renner, M. (author), Bergmann, G. (author), Lyer, S. (author), Blaich, S. (author), Hudler, M. (author), Helmke, B. (author), Gassler, N. (author), Autschbach, F. (author), Ligtenberg, A.J.M. (author), Benner, A. (author), Holmskov, U. (author), Schirmacher, P. (author), Nieuw Amerongen, A.V. (author), Rosenstiel, P. (author), Sina, C. (author), Franke, A. (author), Hafner, M. (author), Kioschis, P. (author), Schreiber, S. (author), Poustka, A. (author), Mollenhauer, J. (author)
Deleted in malignant brain tumors 1 (DMBT1) is a secreted glycoprotein displaying a broad bacterial-binding spectrum. Recent functional and genetic studies linked DMBT1 to the suppression of LPS-induced TLR4-mediated NF-kappaB activation and to the pathogenesis of Crohn's disease. Here, we aimed at unraveling the molecular basis of its function...
article 2009
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Balvers, M.G.J. (author), Verhoeckx, K.C.M. (author), Witkamp, R.F. (author), TNO Kwaliteit van Leven (author)
A sensitive and specific LC-MS/MS method for the quantification of the endocannabinoids and related structures anandamide, 2-arachidonoyl glycerol, 2-arachidonyl glycerol ether, O-arachidonoyl ethanolamide, dihomo-γ-linolenoyl ethanolamide, docosatetraenoyl ethanolamide, N-arachidonoyl dopamine, N-arachidonyl glycine, N-oleoyl dopamine, oleoyl...
article 2009
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Bovet, P.M. (author), Ritts, B.D. (author), Gehrels, G. (author), Abbink, A.O. (author), Darby, B. (author), Hourigan, J. (author), TNO Bouw en Ondergrond (author)
New sedimentologic, stratigraphie, and compositional data from the Paleogene-Neogene stratigraphie succession exposed in the northwest Hexi Corridor and within the North Qilian Shan, provide evidence to suggest that crustal shortening in the North Qilian Shan fold-thrust belt initiated during die Miocene. The section is composed of four...
article 2009
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Meijer, E.A. (author), Nijenhuis, J.N. (author), Vink, R.J.P. (author), Kamphues, F.G. (author), Gielesen, W.L.M. (author), Coatantiec, C. (author), TNO Industrie en Techniek (author)
To measure the relative motions of GAIA's telescopes, the angle between the telescopes is monitored by an all Silicon Carbide Basic Angle Monitoring subsystem (BAM OMA). TNO is developing this metrology system. The stability requirements for this metrology system go into the pico meter and pico radian range. Such accuracies require extreme...
conference paper 2009
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Barbu, A.L. (author), Segers, A.J. (author), Schaap, M. (author), Heemink, A.W. (author), Builtjes, P.J.H. (author), TNO Bouw en Ondergrond (author)
Fine particulate matter (PM) is relevant for human health and its components are associated with climate effects. The performance of chemistry transport models for PM, its components and precursor gases is relatively poor. The use of these models to assess the state of the atmosphere can be strengthened using data assimilation. This study...
article 2009
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Baatjies, R. (author), Lopata, A.L. (author), Sander, I. (author), Raulf-Heimsoth, M. (author), Batemane, E.D. (author), Meijster, T. (author), Heederik, D. (author), Robins, T.G. (author), Jeebhay, M.F. (author), TNO Kwaliteit van Leven (author)
While baker's asthma has been well described, various asthma phenotypes in bakery workers have yet to be characterised. Our study aims to describe the asthma phenotypes in supermarket bakery workers in relation to host risk factors and self-reported exposure to flour dust. A cross-sectional study of 517 supermarket bakery workers in 31 bakeries...
article 2009
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Angelova, N. (author), Kong, H.-W. (author), van de Heijden, R. (author), Yang, S.-Y. (author), Choi, Y.H. (author), Kim, H.K. (author), Wang, M. (author), Hankemeier, T. (author), van der Greef, J. (author), Xu, G. (author), Verpoorte, R. (author), TNO Kwaliteit van Leven (author)
This review summarises the most recent developments in ginseng analysis, in particular the novel approaches in sample pre-treatment and the use of high-performance liquid-chromatography-mass spectrometry. The review also presents novel data on analysing ginseng extracts by nuclear magnetic resonance spectroscopy and high-resolution mass...
article 2008
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Primo-Martín, C. (author), de Beukelaer, H. (author), Hamer, R.J. (author), van Vliet, T. (author), TNO Kwaliteit van Leven (author)
The effect of air and vacuum cooling on the fracture behaviour and accompanying sound emission, moisture content and crispness of bread crust were investigated. Vacuum cooling resulted in rapid evaporative cooling of products that contained high moisture content. Fracture experiments showed a clear dependence of fracture properties on the way...
article 2008
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de Boer, W.E.L. (author), Donceel, P. (author), Brage, S. (author), Rus, M. (author), Willems, J.H.B.M. (author), TNO Kwaliteit van Leven (author)
Background. Decisions on disability pensions are based, among others, on medical reports. The way these medical assessments are performed is largely unclear. The aim of the study was to determine which grounds are used by social insurance physicians (SIPs) in these assessments and to determine if the identification of these grounds can help...
article 2008
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Schouten, L.J. (author), van Dijk, B.A.C. (author), Oosterwijk, E. (author), van Engeland, M. (author), van de Hulsbergen-Kaa, C.A. (author), Kiemeney, L.A.L.M. (author), Goldbohm, R.A. (author), Kester, A. (author), de Vogel, S. (author), Schalken, J.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)
Alcohol consumption has been associated with a decreased risk for renal cell cancer in several studies. We investigated whether alcohol is associated with (epi)genetic changes of the von Hippel-Lindau (VHL) gene in renal cell cancer. The Netherlands Cohort Study (NLCS) on Diet and Cancer started in 1986 (n = 120,852) and uses the case-cohort...
article 2008
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Goede, J. (author), Hack, W.W.M. (author), Sijstermans, K. (author), Pierik, F.H. (author), TNO Kwaliteit van Leven (author)
Pseudoxantoma elasticum (PXE) is a rare chromosomal disorder that results in mineralization of elastic fibers, especially in the skin, eye, and cardiovascular system. Recently, PXE has been associated with testicular microlithiasis (TM),1 which itself might be associated with testicular malignancy.2 Here we report on a 9-year-old boy with PXE...
article 2008
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Janssen, G.M.C.M. (author), Valstar, J.R. (author), van der Zee, S.E.A.T.M. (author), TNO Bouw en Ondergrond (author)
Traveltime determinations have found increasing application in the characterization of groundwater systems. No algorithms are available, however, to optimally design sampling strategies including this information type. We propose a first-order methodology to include groundwater age or tracer arrival time determinations in measurement network...
article 2008
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Spaan, S. (author), Schinkel, J. (author), Wouters, I.M. (author), Preller, L. (author), Tielemans, E. (author), Nij, E.T. (author), Heederik, D. (author), TNO Kwaliteit van Leven (author)
Objectives: Workers in many industries are exposed to endotoxins, which may cause adverse health effects. In exposure assessment, information about exposure variability is essential. However, variability in exposure has rarely been investigated for biological agents and more specifically for endotoxin. Therefore, variance components and...
article 2008
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Tielemans, E. (author), Schneider, T. (author), Goede, H. (author), Tischer, M. (author), Warren, N. (author), Kromhout, H. (author), van Tongeren, M. (author), van Hemmen, J. (author), Cherrie, J.W. (author), TNO Kwaliteit van Leven (author)
The present paper proposes a source-receptor model to schematically describe inhalation exposure to help understand the complex processes leading to inhalation of hazardous substances. The model considers a stepwise transfer of a contaminant from the source to the receptor. The conceptual model is constructed using three components, i.e. (i) the...
article 2008
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Bobeldijk, I. (author), Karlsson, D. (author), Pronk, A. (author), Gonsalves, J. (author), Hekman, M. (author), van de Lagemaat, D. (author), Preller, L. (author), Heederik, D. (author), Skarping, G. (author), TNO Kwaliteit van Leven (author)
An adapted method for the quantitative determination of isocyanates in air was implemented and validated in-house. The method was based on air sampling using an impinger flask containing di-n-butylamine (DBA) in toluene and a glass fibre filter in series. The DBA derivatives were determined using liquid chromatography and tandem mass...
article 2008
Searched for: subject:"Determinants"
(41 - 60 of 142)

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