Searched for: subject:"Determinants"
(1 - 4 of 4)
document
Nielen, M.W.F. (author), van Engelen, M.C. (author), Zuiderent, R. (author), Ramaker, R. (author), TNO Kwaliteit van Leven (author)
An emerging trend is recognised in hormone and veterinary drug residue analysis from liquid chromatography tandem mass spectrometry (LC/MS/MS) based screening and confirmation towards accurate mass alternatives such as LC coupled with time-of-flight (TOF), Fourier transform ion cyclotron resonance (FTICR) or Fourier transform orbitrap (FT...
article 2007
document
Freidig, A.P. (author), Dekkers, S. (author), Verwei, M. (author), Zvinavashe, E. (author), Bessems, J.G.M. (author), van de Sandt, J.J.M. (author), TNO Kwaliteit van Leven (author)
Future EU legislations enforce a fast hazard and risk assessment of thousands of existing chemicals. If conducted by means of present data requirements, this assessment will use a huge number of test animals and will be neither cost nor time effective. The purpose of the current research was to develop methods to increase the acceptability of in...
article 2007
document
Zuang, V. (author), Alonso, M.A. (author), Botham, P.A. (author), Eskes, C. (author), Fentem, J. (author), Liebsch, M. (author), van de Sandt, J.J.M. (author), TNO Kwaliteit van Leven (author)
article 2005
document
van den Berg, K.J. (author), Lammers, J.H.C.M. (author), Hoogendijk, E.M.G. (author), Kulig, B.M. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Adult male WAG/Rij/MBL rats were dosed with lead acetate at 0, 4.0, 8.0 or 12.5 mg/kg, 5 days per week for 4 weeks. Animals were assessed prior to exposure, at the end of the 4-week exposure period and after a 2-week recovery period using a functional observational battery (FOB) and motor activity assessment. Rats were sacrificed two weeks after...
article 1996
Searched for: subject:"Determinants"
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