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Cai, M. (author), van Buuren, S. (author), Vink, G. (author)In most medical research, the average treatment effect is used to evaluate a treatment's performance. However, precision medicine requires knowledge of individual treatment effects: What is the difference between a unit's measurement under treatment and control conditions? In most treatment effect studies, such answers are not possible because...article 2022
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Li, L. (author), Hoefsloot, H. (author), de Graaf, A.A. (author), Acar, E. (author), Smilde, A.K. (author)Background: Analysis of dynamic metabolomics data holds the promise to improve our understanding of underlying mechanisms in metabolism. For example, it may detect changes in metabolism due to the onset of a disease. Dynamic or time-resolved metabolomics data can be arranged as a three-way array with entries organized according to a subjects...article 2022
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Regeer, H. (author), Nieuwenhuijse, E.A. (author), Vos, R.C. (author), Kiefte-de Jong, J.C. (author), van Empelen, P. (author), de Koning, E.J.P. (author), Bilo, H.J.G. (author), Huisman, S.D. (author)Aims: To investigate changes in physical activity (PA) and psychological factors during societal lockdown in people with type 2 diabetes. Methods: A cross-sectional study among Dutch adults with type 2 diabetes. Data were collected using online questionnaires. A multivariate multinomial logistic regression was performed with change in PA during...article 2021
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Austin, P.C. (author), White, I.R. (author), Lee, D.S. (author), van Buuren, S. (author)Missing data is a common occurrence in clinical research. Missing data occurs when the value of the variables of interest are not measured or recorded for all subjects in the sample. Common approaches to addressing the presence of missing data include complete-case analyses, in which subjects with missing data are excluded, or mean-value...article 2021
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van Egmond, M.B. (author), Spini, G. (author), van der Galien, O. (author), IJpma, A. (author), Veugen, P.J.M. (author), Kaaij, W. (author), Sangers, A. (author), Rooijakkers, T. (author), Langenkamp, P. (author), Kamphorst, B. (author), van de L'Isle, N. (author), Kooij-Janic, M. (author)Background: Recent developments in machine learning have shown its potential impact for clinical use such as risk prediction, prognosis, and treatment selection. However, relevant data are often scattered across diferent stakehold ers and their use is regulated, e.g. by GDPR or HIPAA. As a concrete use-case, hospital Erasmus MC and health...article 2021
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de Bruin-Hoegee, J.M. (author), Kleiweg, D. (author), Noort, D. (author), van Asten, A.C. (author)Chemical attribution typically aims to establish a link between material found at a crime scene and a person, location or other evidence. In the field of illicit drugs, chemical attribution signatures are usually impurity profiles. Extending these to metabolized samples would create new possibilities in forensic investigations. The present study...article 2021
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- Diran, D.D.D. (author), Hoppe, T. (author), Ubacht, J. (author), Slob, A. (author), Blok, K. (author) article 2020
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Verhoosel, J.P.C. (author), Nouwt, B. (author), Bakker, R.M. (author), Sapounas, A. (author), Slager, A.A. (author)In this paper, we deal with the challenge of semantic alignment of different data sources in the horticultural sector. In this sector, greenhouses are used to grow vegetables and plants and the main goal for a greenhouse grower is to control the climate such that crop is optimally cultivated against the lowest cost. Combining available data...conference paper 2019
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- Sprung, D. (author), Sucher, E. (author), Grossmann, P. (author), Kociok, T. (author), van Eijk, A.M.J. (author), Stein, K. (author) conference paper 2019
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Verhaegen, J. (author), Weltje, G.J. (author), Munsterman, D.K. (author)The field of provenance analysis has seen a revival in the last decade as quantitative dataacquisition techniques continue to develop. In the 20th century, many heavy-mineral data were collected. These data were mostly used as qualitative indications for stratigraphy and provenance, and not incorporated in a quantitative provenance methodology....article 2018
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Koopmans, L. (author), Damen, N. (author), Wagner, C. (author)Objectives Many European countries face challenges in long-term care for older people, such as the growing number of older people requiring care, the increasing complexity of their health care problems, and a decreasing workforce that is inadequately prepared. Optimizing the staff and skill mix of health care teams may offer part of the solution...article 2018
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Verhoosel, J.P.C. (author), van Bekkum, M. (author), Verwaart, T. (author)Food supply chains consist of many links and operate on a global scale with many stakeholders involved from farm to fork. Each stakeholder maintains data about food products that they handle, but this data is not transparently available to all stakeholders in the chain and trust in data sharing is low. In addition, there are various other data...article 2018
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Frank Phillipson, F. (author), Ortega del Vecchyo, M. (author), van Ginkel, B. (author), Huizing, S. (author), Sangers, A. (author)In logistic delivery chains time windows are common. An arrival has to be in a certain time interval, at the expense of waiting time or penalties if the time limits are exceeded. This paper looks at the optimal placement of those time intervals in a specific case of a barge visiting two ports in sequence. For the second port a possible delay or...conference paper 2017
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van Leeuwen, C.J. (author), van Huis, J.R. (author), Baan, J. (author)Wide Area Motion Imagery (WAMI) enables image based surveillance of areas that can cover multiple square kilometers. Interpreting and analyzing information from such sources, becomes increasingly time consuming as more data is added from newly developed methods for information extraction. Captured from a moving Unmanned Aerial Vehicle (UAV), the...conference paper 2016
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Kruithof, M.C. (author), Bouma, H. (author), Fischer, N.M. (author), Schutte, K. (author)Object recognition is important to understand the content of video and allow flexible querying in a large number of cameras, especially for security applications. Recent benchmarks show that deep convolutional neural networks are excellent approaches for object recognition. This paper describes an approach of domain transfer, where features...conference paper 2016
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Rottenkolber, M. (author), Voogd, E. (author), van Dijk, L. (author), Primatesta, P. (author), Becker, C. (author), de Groot, M.C.H. (author), Plana, E. (author), Alvarez, Y. (author), Durand, J. (author), Slattery, J. (author), Afonso, A. (author), Requena, G. (author), Huerta, C. (author), Alvarez, A. (author), de Abajo, F. (author), Tauscher, M. (author), Hasford, J. (author), Fischer, R. (author), Reynolds, R. (author), Schmiedl, S. (author)Background: For patients with asthma, COPD, or asthma-COPD overlap syndrome (ACOS), inter-country comparisons of seasonal changes in drug prescriptions are scarce or missing. Hence, we aimed to compare seasonal changes in prescription rates of long-acting beta-2-agonist (LABA) in four European countries. Methods: A common study protocol was...article 2015
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Verhoosel, J.P.C. (author), van Bekkum, M.A. (author), van Evert, F.K. (author)This paper addresses the use of ontologies for combining different sensor data sources to enable big data analysis in the dairy farming domain. We have made existing data sources accessible via linked data RDF mechanisms using OWL ontologies on Virtuoso and D2RQ triple stores. In addition, we have created a common ontology for the domain and...conference paper 2015
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Goelela, V.S. (author), Kelder, T. (author), Adriaens, M.E. (author), Evelo, C.T. (author), Radonijc, M. (author)Background Illumina whole-genome expression bead arrays are a widely used platform for transcriptomics. Most of the tools available for the analysis of the resulting data are not easily applicable by less experienced users. ArrayAnalysis.org provides researchers with an easy-to-use and comprehensive interface to the functionality of R and...article 2015
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Smit, S.K. (author), van der Vecht, B. (author), Lebesque, L.H.E.M. (author)Predictive mapping of crime and anti-social behaviour is becoming more and more popular as a tool to support police and policy makers. Important ingredients of such models are often demographic and economic characteristics of the area. Since those are hard to influence, we propose to use the environment instead. In this paper, we present a model...article 2014
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- Smit, S.K. (author), van der Vecht, B. (author), Lebesque, L.H.E.M. (author) report 2013