Searched for: subject:"DNA%5C+viruses"
(1 - 4 of 4)
document
Geutskens, S.B. (author), van der Eb, M.M. (author), Plomp, A.C. (author), Jonges, L.E. (author), Cramer, S.J. (author), Ensink, N.G. (author), Kuppen, P.J.K. (author), Hoeben, R.C. (author)
The host-immune response against adenoviruses forms a major obstacle for their use as gene therapy vectors for treatment of genetic defects. None the less, they are the preferred vectors for in vivo gene transfer in experimental gene therapy protocols for cancer. In this article we demonstrate the antitumor efficacy of adenovirus-mediated...
article 2000
document
de Mik, G. (author), de Groot, I. (author), Medisch Biologisch Laboratorium TNO Chemisch Laboratorium TNO (author)
The mechanisms of inactivation of aerosolized bacteriophage phiX174 in atmospheres containing ozone, cyclohexene, or ozonized cyclohexene were studied by using 32P-labelled phage. The inactivation of the aerosolized phage in clean air or in air containing cyclohexene is due to damage of the protein coat since the deoxyribonucleic acid (DNA)...
article 1977
document
de Mik, G. (author), de Groot, I. (author), Gerbrandy, J.L.F. (author), Medisch Biologisch Laboratorium TNO Chemisch Laboratorium TNO (author)
The effects of ozone and ozonized olefins on aerosol survival of bacteriophage phiX174 were studied. The ozone concentrations used were between 0 and 110 parts/109, giving decay rates up to 0.03 min-1. The olefins used were trans 2 butene and cyclohexene in concentrations of 500 parts/109 and 2.4 parts/106, respectively. Olefins alone have no...
article 1977
document
van Hemmen, J.J. (author), Meuling, W.J.A. (author), Bleichrodt, J.F. (author), Medisch Biologisch Laboratorium TNO (author)
The radiosensitization by oxygen of biologically active bacteriophage DNA in bacterial extracts was studied. The oxygen effect in such a system appeared not to be due or only to a minor extent to the presence of endogenous sulphydryl compounds. The components in a cell extract which enable oxygen and other sensitizers to sensitize DNA could not...
article 1974
Searched for: subject:"DNA%5C+viruses"
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