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Botschuijver, S. (author), Welting, O. (author), Levin, E. (author), Maria-Ferreira, D. (author), Koch, E. (author), Montijn, R.C. (author), Seppen, J. (author), Hakvoort, T.B.M. (author), Schuren, F.H.J. (author), de Jonge, W.J. (author), van den Wijngaard, R.M. (author)Background: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder associated with altered gastrointestinal microflora and increased nociception to colonic distension. This visceral hypersensitivity can be reversed in our rat maternal separation model by fungicides. Menthacarin® is a proprietary combination of essential oils from...article 2018
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TNO Kwaliteit van Leven (author), Gautam, R. (author), Borgdorff, H. (author), Jespers, V. (author), Francis, S.C. (author), Verhelst, R. (author), Mwaura, M. (author), Delany-Moretlwe, S. (author), Ndayisaba, G. (author), Kyongo, J.K. (author), Hardy, L. (author), Menten, HJ. (author), Crucitti, T. (author), Tsivtsivadze, E. (author), Schuren, F. (author), van de Wijgert, J.H.R.M. (author), Vaginal biomarkers Study Group, (author)Background: Sociodemographic, behavioral and clinical correlates of the vaginal microbiome (VMB) as characterized by molecular methods have not been adequately studied. VMB dominated by bacteria other than lactobacilli may cause inflammation, which may facilitate HIV acquisition and other adverse reproductive health outcomes. Methods: We...article 2015
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Belzer, C. (author), Gerber, G.K. (author), Roeselers, G. (author), Delaney, M. (author), DuBois, A. (author), Liu, Q. (author), Belavusava, V. (author), Yeliseyev, V. (author), Houseman, A. (author), Onderdonk, A. (author), Cavanaugh, C. (author), Bry, L. (author)Longitudinal studies of the microbiota are important for discovering changes in microbial communities that affect the host. The complexity of these ecosystems requires rigorous integrated experimental and computational methods to identify temporal signatures that promote physiologic or pathophysiologic responses in vivo. Employing a murine model...article 2014
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Venema, K. (author), Maathuis, A.J.H. (author), TNO Voeding (author)A polymerase chain reaction (PCR)-based method was developed for the identification of isolates of Bifidobacterium at the species level. Using two Bifidobacterium-specific primers directed against the 16S ribosomal gene (Bif164 and Bif662), a PCR product was obtained from the type strains of 12 different bifidobacterial species that have been...article 2003