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Dukalski, M. (author), Rovetta, D. (author), van der Linde, S.G. (author), Möller, M. (author), Neumann, N. (author), Phillipson, F. (author)Much of recent progress in geophysics can be attributed to the adaptation of heterogeneous high-performance computing architectures. It is projected that the next major leap in many areas of science, and hence hopefully in geophysics too, will be due to the emergence of quantum computers. Finding a right combination of hardware, algorithms, and...article 2023
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Tielman, M.L. (author), Neerincx, M.A. (author), Brinkman, W.P. (author)BACKGROUND: Systems incorporating virtual agents can play a major role in electronic-mental (e-mental) health care, as barriers to care still prevent some patients from receiving the help they need. To properly assist the users of these systems, a virtual agent needs to promote motivation. This can be done by offering motivational messages....article 2019
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Toet, A. (author)We have tested whether natural dynamic backgrounds affect perceived facial dominance. Facial evaluation is based on just two fundamental dimensions of facial appearance: valence and dominance. Perceived facial valence has been shown to be biased towards background valence. However, it is currently unknown, if the perception of facial dominance...article 2016
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van Loon, K. (author), Breteler, M.J.M. (author), van Wolfwinkel, L. (author), Rheineck Leyssius, A.T. (author), Kossen, A.S. (author), Kalkman, C.J. (author), van Zaane, B. (author), Peelen, L.M. (author)Altered respiratory rate is one of the first symptoms of medical conditions that require timely intervention, e.g., sepsis or opioid-induced respiratory depression. To facilitate continuous respiratory rate monitoring on general hospital wards a contactless, non-invasive, prototype monitor was developed using frequency modulated continuous wave...article 2016
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Velikova, M. (author), Dutra, I. (author), Burnside, E.S. (author)The development and use of computerized decision-support systems in the domain of breast cancer has the potential to facilitate the early detection of diseasebookPart 2015
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Klaver, M.H.A. (author), Boltjes, B. (author), Croom-Jonson, S. (author), Jonat, F. (author), Çankaya, Y. (author)The rapidly evolving environment of Cyber threats against the NATO Alliance has necessitated a renewed focus on the development of Cyber Defence policy and capabilities. The NATO Modelling and Simulation Group is looking for ways to leverage Modelling and Simulation experience in research, analysis and training to assist the Cyber Defence...conference paper 2014
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Bakker, L.E.H. (author), Boon, M.R. (author), van der Linden, R.A.D. (author), Arias-Bouda, L.P. (author), van Klinken, J.B. (author), Smit, F. (author), Verberne, H.J. (author), Jukema, J.W. (author), Tamsma, J.T. (author), Havekes, L.M. (author), van Marken Lichtenbelt, W.D. (author), Jazet, I.M. (author), Rensen, P.C.N. (author)Background: Individuals of south Asian origin have a very high risk of developing type 2 diabetes compared with white Caucasians. We aimed to assess volume and activity of brown adipose tissue (BAT), which is thought to have a role in energy metabolism by combusting fatty acids and glucose to produce heat and might contribute to the difference...article 2014
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Peironcely, J.E. (author), Rojas-Chertó, M. (author), Fichera, D. (author), Reijmers, T. (author), Coulier, L. (author), Faulon, J.-L. (author), Hankemeier, T. (author)Computer Assisted Structure Elucidation has been used for decades to discover the chemical structure of unknown compounds. In this work we introduce the first open source structure generator, Open Molecule Generator (OMG), which for a given elemental composition produces all non-isomorphic chemical structures that match that elemental...article 2012
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Blanson Henkemans, O.A. (author), Rogers, W.A. (author), Dumay, A.M.C. (author)Objective: Contribute to understanding of determinants of attrition in Randomized Controlled Trials (RCTs) on eHealth services for self-care and to developing a strategy to attend to them. Background RCTs are considered the "gold standard" in empirical research on medical interventions. However, RCTs of eHealth services for selfcare are often...article 2011
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Peters, E. (author), Wilschut, F. (author), Leeuwenburgh, O. (author), van Hooff, P.M.E. (author)Increasingly computer assisted techniques are used for history matching reservoir models. Such methods will become indispensable in view of the increasing amount of information generated by intelligent wells, in which case manual interpretation becomes too time consuming. Also, with the increasing possibilities for controlling a reservoir, a...conference paper 2011
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Naber, R.C.G. (author), Asadi, K. (author), Blom, P.W.M. (author), de Leeuw, D.M. (author), de Boer, B. (author), TNO Industrie en Techniek (author)A memory functionality is a prerequisite for many applications of electronic devices. Organic nonvolatile memory devices based on ferroelectricity are a promising approach toward the development of a low-cost memory technology. In this Review Article we discuss the latest developments in this area with a focus on three of the most important...article 2010
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Kerstholt, J.H. (author), van der Zwaard, F. (author), Bart, H. (author), Cremers, A. (author), TNO Defensie en Veiligheid (author)Background. Most terminally ill patients prefer to die at home rather than at an institution. However, patients are often insufficiently aware of the downsides of staying at home, which signals a need for effective decision aids. Objectives. The main purpose of the present study was to compare indirect methods of value elicitation (personal...article 2009
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An online lifestyle diary with a persuasive computer assistant providing feedback on self-managementBlanson Henkemans, O.A. (author), van der Boog, P.J.M. (author), Lindenberg, J. (author), van der Mast, C.A.P.G. (author), Neerincx, M.A. (author), Zwetsloot-Schonk, B.J.H.M. (author), TNO Defensie en Veiligheid (author)In accordance with the global trend, in The Netherlands approximately 45% of the population is overweight. Existing studies show that patient self-management can reduce these figures, but medical non-adherence is a persistent problem. eHealth can potentially increase adherence to self-management. Consequently, we designed a persuasive computer...article 2009
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TNO Kwaliteit van Leven (author), Samoocha, D. (author), Bruinvels, D.J. (author), Anema, R.J. (author), Steenbeek, R. (author), Beek, A.J.V.D. (author)Background. Individuals claiming a disability benefit after long-term sickness absence, have to undergo medical disability assessments. These assessments, often carried out by specialized physicians, can be complicated by wrong expectations or defensive attitudes of disability benefit claimants. It is hypothesized that empowerment of these...article 2009
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Blanson Henkemans, O.A. (author), Sawirjo, V.M. (author), van der Mast, C.A.P.G. (author), Neerincx, M.A. (author), Lindenberg, J. (author), TNO Defensie en Veiligheid (author)Patients suffering from chronic illness, such as diabetes, use various domestic instruments as part of their selfcare. For older adults, there is a need for assistance to use the instruments adequately and to solve technical failures. Following the eHealth concept, we designed a computer assistant for an older adult and a technical specialist,...conference paper 2008
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Blanson Henkemans, O.A. (author), Rogers, W.A. (author), Fisk, A.D. (author), Neerincx, M.A. (author), Lindenberg, J. (author), van der Mast, C.A.P.G. (author)Objectives: We developed an adaptive computer assistant for the supervision of diabetics' self-care, to support limiting illness and need for acute treatment, and improve health literacy. This assistant monitors self-care activities logged in the patient's electronic diary. Accordingly, it provides context-aware feedback. The objective was to...article 2008
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Wesselink, J.M. (author), Berkhoff, A.P. (author), TNO Industrie en Techniek (author)In this paper, real-time results are given for broadband multichannel active noise control using the regularized modified filtered-error algorithm. As compared to the standard filtered-error algorithm, the improved convergence rate and stability of the algorithm are obtained by using an inner-outer factorization of the transfer path between the...article 2008
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Santos, A.F. (author), Zaltsman, A.B. (author), Martin, R.C. (author), Kuzmin, A. (author), Alexandrov, Y. (author), Roquemore, E.P. (author), Jessop, R.A. (author), Erck, M.G.M.V. (author), Verheijen, J.H. (author), TNO Kwaliteit van Leven (author)Angiogenesis is a general term describing formation of new tube-like microvessel sprouts that are the size of capillary blood vessels. Angiogenesis is fundamental in key stages of embryonic development, organ formation, and wound repair and is also involved in the development and progression of a variety of pathological conditions, including...article 2008
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Strik, H. (author), Truong, K. (author), de Wet, F. (author), Cucchiarini, C. (author), TNO Defensie en Veiligheid (author)Providing feedback on pronunciation errors in computer assisted language learning systems requires that pronunciation errors be detected automatically. In the present study we compare four types of classifiers that can be used for this purpose: two acoustic-phonetic classifiers (one of which employs linear-discriminant analysis (LDA)), a...conference paper 2007
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Jacobusse, G. (author), van Buuren, S. (author), TNO Kwaliteit van Leven (author)Developmental indicators that are used for routine measurement in The Netherlands are usually chosen to optimally identify delayed children. Measurements on the majority of children without problems are therefore quite imprecise. This study explores the use of computerized adaptive testing (CAT) to monitor the development of young children. CAT...article 2007