Searched for: subject:"Comorbidity"
(1 - 20 of 20)
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Giordano, L. (author), Mihaila, S.M. (author), Eslami Amirabadi, H. (author), Masereeuw, R. (author)
Chronic kidney disease (CKD) typically appears alongside other comorbidities, highlighting an underlying complex pathophysiology that is thought to be vastly modulated by the bidirectional gut–kidney crosstalk. By combining advances in tissue engineering, biofabrication, microfluidics, and biosensors, microphysiological systems (MPSs) have...
article 2021
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Lankhaar, J.A.C. (author), Kemler, E. (author), Hofstetter, H. (author), Collard, D.C.M. (author), Zelissen, P.M.J. (author), Stubbe, J.H. (author), Backx, F.J.G. (author)
Awareness of physical activity (PA) constraints in patients with primary hypothyroidism on thyroid hormone replacement therapy (THR) is important. Hence, this cross-sectional matched case-control study aimed to determine PA and sports participation (SP) in patients with hypothyroidism on THR in comparison to control subjects. Accordingly, survey...
article 2021
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Vugteveen, J. (author), de Bildt, A. (author), Hartman, C.A. (author), Reijneveld, S.A. (author), Timmerman, M.E. (author)
The Strengths and Difficulties Questionnaire (SDQ) is widely used, based on evidence of its value for screening. This evidence primarily regards the single informant total difficulties scale and separate difficulties subscales. We assessed to what degree adolescents' SDQ profiles that combined all self- and parent-rated subscales were associated...
article 2020
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Kruisdijk, F. (author), Deenik, J. (author), Yenback, D. (author), Tak, E.C. (author), van Harten, P. (author), Hopman-Rock, M. (author), Hendriksen, I. (author)
Sedentary behaviour and lack of physical activity threatens health. Research concerning these behaviours of inpatients with severe mental illness is limited but urgently needed to reveal prevalence and magnitude. In total, 184 inpatients (men n =108, women n =76, mean age 57,4, 20% first generation antipsychotics, 40% second generation...
article 2017
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van der Valk, E.S. (author), Smans, L.C.C.J. (author), Hofstetter, H. (author), Stubbe, J.H. (author), de Vries, M. (author), Backx, F.J.G. (author), Hermus, A.R.M.M. (author), Zelissen, P.M.J. (author)
Background: Health-related quality of life in patients with Addison's disease has been assessed in various European countries, indicating a reduced quality of life. However, no studies have addressed the impact of Addison's disease on physical activity. Objective: The aim of this study was to investigate the quality of life in Dutch patients...
article 2016
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Morrison, M.C. (author), Kleemann, R. (author)
Obesity is associated with a chronic low-grade inflammatory state that drives the -development of obesity-related co-morbidities such as insulin resistance/type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), and cardiovascular disease. This metabolic inflammation is thought to originate in the adipose tissue, which becomes inflamed and...
article 2015
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Groothuis-Oudshoorn, C.G.M. (author), Chorus, A.M.J. (author), Verrips, G.H.W. (author), Detmar, S.B. (author)
BACKGROUND: The London Handicap Scale (LHS) was found to be a valid and reliable scale for measuring participation restrictions in adults. OBJECTIVE: This paper describes the development and assesses the construct-related validity of a Dutch version of the London Handicap Scale (DLHS). METHODS: The DLHS was tested in 798 adults (mean age: 50.7...
article 2015
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Zaadstra, B.M. (author), Chorus, A.M.J. (author), van Buuren, S. (author), Kalsbeek, H. (author), van Noort, J.M. (author), TNO Defensie en Veiligheid TNO Kwaliteit van Leven (author), DenV KvL (author)
Previous studies have suggested an association between multiple sclerosis (MS) and infectious mononucleosis (IM) but data on the exact strength of this association or its selectivity have been conflicting. In this study we have evaluated the association between MS and a variety of common childhood infections and afflictions in a large population...
article 2008
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Eijkemans, M. (author), Mommers, M. (author), de Vries, S.I. (author), van Buuren, S. (author), Stafleu, A. (author), Bakker, I. (author), Thijs, C. (author), TNO Kwaliteit van Leven (author)
OBJECTIVE. Prevalence of asthma and overweight has increased simultaneously during the past decades. Several studies have reported an association between these two health problems, but it is unclear whether this relation is causal. We hypothesize that children with asthmatic symptoms are less physically active, which may contribute to the...
article 2008
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Kaptein, S. (author), Jansen, D.E.M.C. (author), Vogels, A.G.C. (author), Reijneveld, S.A. (author), TNO Kwaliteit van Leven (author)
Background: The assessment of mental health problems in children with intellectual disability (ID) mostly occurs by filling out long questionnaires that are not always validated for children without ID. The aim of this study is to assess the differences in mental health problems between children with ID and without ID, using a short...
article 2008
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Verheijden, M.W. (author), Jans, M.P. (author), Hildebrandt, V.H. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)
Background: In recent years, many tailored lifestyle counseling programs have become available through the Internet. Previous research into such programs has shown selective enrollment of relatively healthy people. However, because of the known dose-response relationship between the intensity and frequency of counseling and the behavior change...
article 2007
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van Oyen, H. (author), Heyden, J. (author), Perenboom, R. (author), Jagger, C. (author), TNO Preventie en Gezondheid (author)
Objective: To evaluate a single item instrument, the Global Activity Limitation Indicator (GALI), to measure long-standing health related activity limitations, against several health indicators: a composite morbidity indicator, instruments measuring mental health (SCL-90R, GHQ-12), physical co-morbidity and physical limitations (ADLs, SF-36)....
article 2006
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Kremer, A.M. (author), Pal, T.M. (author), Keimpema, A.R.J. (author), TNO Kwaliteit van Leven (author)
Objectives: The aim was to gain insight into work experiences and problems of subjects with chronic obstructive pulmonary disease (COPD) to develop more effective guidelines for preventing work disability and work loss. Methods: A total of 617 patients aged 45-60, recruited from pulmonary outpatient clinics and general practices, completed a...
article 2006
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Bousquet, J. (author), Demarteau, N. (author), Mullol, J. (author), van den Akker-van Marle, M.E. (author), van Ganse, E. (author), Bachert, C. (author), TNO Preventie en Gezondheid (author)
Background: Allergic rhinitis was recently classified by the ARIA guidelines as persistent or intermittent. Levocetivizine was shown to improve symptoms and health-related quality of life of patients with persistent allergic rhinitis in the XPERT™ study, a 6-month randomized double blind placebo-controlled trial. Objective: To assess the total...
article 2005
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Reijneveld, S.A. (author), Crone, M.R. (author), Verhulst, F.C. (author), Verloove-Vanhorick, S.P. (author)
Background: Disasters greatly affect the mental health of children and adolescents, but quantification of such effects is difficult. Using prospective predisaster and postdisaster data for affected and control populations, we aimed to assess the effects of a severe disaster on the mental health and substance use of adolescents. Methods: In...
article 2003
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de Beer, F. (author), Stalenhoef, A.F.H. (author), Hoogerbrugge, N. (author), Kastelein, J.J.P. (author), Leuven, J.A.G. (author), van Duijn, C.M. (author), Havekes, L.M. (author), Smelt, A.H.M. (author), Gaubius Instituut TNO (author)
Type III hyperlipoproteinemia (HLP) is mainly found in homozygous carriers of apolipoprotein E2 (apoE2, Arg158→Cys). Only a small percentage (<5%) of these apoE2 homozygotes develops hyperlipidemia, indicating that additional environmental and genetic factors contribute to the expression of type III HLP. In the present study, first, the...
article 2002
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Vermeulen, E.G.J. (author), Niessen, H.W.M. (author), Bogels, M. (author), Stehouwer, C.D.A. (author), Rauwerda, J.A. (author), van Hinsbergh, V.W.M. (author), Gaubius Instituut TNO (author)
The aim of this study was to determine whether the morphology of the muscular femoral artery in patients with atherosclerosis and hyperhomocysteinemia differs from that of atherosclerotic vessels from patients with normal homocysteine levels. Whole-vessel biopsies of the superficial femoral artery were taken from patients with symptomatic...
article 2001
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Sprangers, M.A.G. (author), de Regt, E.B. (author), Andries, F. (author), van Agt, H.M.E. (author), Bijl, R.V. (author), de Boer, J.B. (author), Foets, M. (author), Hoeymans, N. (author), Jacobs, A.E. (author), Kempen, G.I.J.M. (author), Miedema, H.S. (author), Tijhuis, M.A.R. (author), de Haes, H.C.J.M. (author), NIA TNO (author)
The objective of the present study is to compare the QL of a wide range of chronic disease patients. Secondary analysis of eight existing data sets, including over 15,000 patients, was performed. The studies were conducted between 1993 and 1996 and included population-based samples, referred samples, consecutive samples, and/or consecutive...
article 2000
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Hopman-Rock, M. (author), Odding, E. (author), Hofman, A. (author), Kraaimaat, F.W. (author), Bijlsma, J.W.J. (author), TNO Preventie en Gezondheid (author)
Objective. To determine differences in health status of people aged 55 to 74 years with pain in the hip or knee only and with additional mobility restricting conditions. Methods. A subsample from a community based study on pain, disability, comorbidity, and radio-logical osteoarthritis (OA) was used to identify a group with current pain in the...
article 1997
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George, E.K. (author), Mearin, M.L. (author), Franken, H.C.M. (author), Houwen, R.H.J. (author), Hirasing, R.A. (author), Vandenbroucke, J.P. (author)
Background - The incidence of coeliac disease varies internationally. Aims - To assess the incidence of childhood coeliac disease in The Netherlands and to study the clinical features and the presence of associated disorders. Subjects - Identified cases of childhood coeliac disease in The Netherlands in 1993-4 by means of the Dutch Paediatric...
article 1997
Searched for: subject:"Comorbidity"
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