Blommaert, F.A. (author), Floot, B.G.J. (author), van Dijk-Knijnenburg, H.C.M. (author), Berends, F. (author), Baan, R.A. (author), Schornagel, J.H. (author), den Engelse, L. (author), Fichtinger-Schepman, A.M.J. (author), Centraal Instituut voor Voedingsonderzoek TNO (author) We have studied the formation and repair of cisplatin-DNA adducts in wild-type mouse leukemia L1210/0 cells and in the sublines L1210/2 and L1210/5, which differ in cisplatin sensitivity. In a colony-formation assay these sublines were 9- and 22-fold more resistant compared to L1210/0, respectively. Cisplatin-induced DNA modification was studied...
article 1998