- document
-
Rasmussen, B. (author), Gerretsen, E. (author), TNO Industrie en Techniek (author)ISO 140 is the basic series of standards in Building Acoustics and consists of several parts relating to laboratory and field measurements. The standards were originally prepared by ISO/TC43/SC2 WGs in the early sixties and since then updated and implemented as European standards through CEN/TC126. The ISO 140 series now consists of more than 10...conference paper 2005
- document
-
Litjens, R. (author)Using an operator perspective, we present a flow level capacity comparison of an HSDPA and a typically deployed release ‘99-based UMTS network, both in a qualitative and quantitative sense. The purpose of the qualitative reasoning is to generate a solid intuitive understanding of the HSDPA benefits. In the quantitative study, we resolve a number...conference paper 2005
- document
-
te Biesebeke, R. (author), Record, E. (author), van Biezen, N. (author), Heerikhuisen, M. (author), Franken, A. (author), Punt, P.J. (author), van den Hondel, C.A.M.J.J. (author), TNO Kwaliteit van Leven (author)To study the relation between the number of hyphal tips and protein secretion during growth on a solid substrate, we have constructed two mutant strains of Aspergillus oryzae with increased hyphal branching. We have analysed hydrolytic enzyme activities during growth on wheat kernels (WK) of A. oryzae strains carrying the disrupted allele of the...article 2005
- document
-
The solvent-tolerant Pseudomonas putida S12 as host for the production of cinnamic acid from glucoseNijkamp, K. (author), van Luijk, N. (author), de Bont, J.A.M. (author), Wery, J. (author), TNO Kwaliteit van Leven TNO Voeding (author)A Pseudomonas putida S12 strain was constructed that efficiently produced thefine chemical cinnamic acid from glucose or glycerol via the central metabolite phenylalanine. The gene encoding phenylalanine ammonia lyase from the yeast Rhodosporidium toruloides was introduced. Phenylalanine availability was the main bottleneck in cinnamic acid...article 2005
- document
-
Joosten, V. (author), Roelofs, M.S. (author), van den Dries, N. (author), Goosen, T. (author), Verrips, C.T. (author), van den Hondel, C.A.M.J.J. (author), Lokman, B.C. (author), TNO Kwaliteit van Leven (author)The Arthromyces ramosus peroxidase gene (arp) was genetically fused to either the 5′- or 3′-terminal ends of the gene encoding llama variable heavy chain antibody fragment VHH R9, resulting in the fusion expression cassettes ARP-R9 or R9-ARP. Aspergillus awamori transformants were obtained which produced up to 30 mg l-1 fusion protein in the...article 2005
- document
-
Pieterse, B. (author), Leer, R.J. (author), Schuren, F.H.J. (author), van der Werf, M.J. (author), TNO Kwaliteit van Leven (author)The organic acid lactate is the predominant fermentation product of Lactobacillus plantarum. The undissociated form of this organic acid is a strong growth inhibitor for the organism. Different theories have been postulated to explain the inhibitory effects of lactic acid: (i) toxicity arising from the dissipation of the membrane potential, (ii)...article 2005
- document
-
Endrayanto, A.I. (author), van Berg, H.D. (author), Boucherie, R.J. (author)This paper models and analyzes downlink and uplink power assignment in code division multiple access (CDMA) mobile networks. By discretizing the area into small segments, the power requirements are characterized via a matrix representation that separates user and system characteristics. We obtain a closed-form analytical expression of the so...article 2005
- document
-
TNO Kwaliteit van Leven (author), Damveld, R.A. (author), Arentshorst, M. (author), van Kuyk, P.A. (author), Klis, F.M. (author), van den Hondel, C.A.M.J.J. (author), Ram, A.F.J. (author)Glycosylphosphatidylinositol (GPI)-anchored proteins in fungi are found at the cell surface, either as plasma membrane proteins (GPI-PMPs) or attached by a remnant of the GPI-anchor to the cell wall (GPI-CWPs). GPI-CWPs can be extracted from the cell wall by treatment with hydrofluoric acid (HF), which cleaves the phosphodiester bond that is...article 2005
- document
-
Ram, A.F.J. (author), Arentshorst, M. (author), Damveld, R.A. (author), van Kuyk, P.A. (author), Klis, F.M. (author), van den Hondel, C.A.M.J.J. (author), TNO Voeding (author)Perturbation of cell wall synthesis in Saccharomyces cerevisiae, either by mutations in cell wall synthesis-related genes or by adding compounds that interfere with normal cell wall assembly, triggers a compensatory response to ensure cell wall integrity. This response includes an increase in chitin levels in the cell wall. Here it is shown that...article 2004
- document
-
van Hijum, S.A.F.T. (author), Szalowska, E. (author), van der Maarel, M.J.E.C. (author), Dijkhuizen, L. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)Lactobacillus reuteri strain 121 employs a fructosyltransferase (FTF) to synthesize a fructose polymer [a fructan of the levan type, with β(2→6) linkages] from sucrose or raffinose. Purification of this FTF (a levansucrase), and identification of peptide amino acid sequences, allowed isolation of the first Lactobacillus levansucrase gene (lev),...article 2004
- document
-
Majhenič, A.Č. (author), Venema, K. (author), Allison, G.E. (author), Matijašić, B.B. (author), Rogelj, I. (author), Klaenhammer, T.R. (author), TNO Voeding (author)Lactobacillus gasseri LF221, an isolate from the feces of a child, produces two bacteriocins. Standard procedures for molecular techniques were used to locate, clone and sequence the fragments of LF221 chromosomal DNA carrying the acidocin LF221 A and B structural genes, respectively. Sequencing analysis revealed the gene of acidocin LF221 A to...article 2004
- document
-
Rodríguez-Sánchez, R. (author), Fdez-Valdivia, J. (author), Toet, A. (author), García, J.A. (author), TNO Technische Menskunde (author)The goal of this paper is to analyze the relation between the visual distinctness and the priority assigned to the information in two di2erent progressive transmission schemes: the Set Partitioning in Hierarchical Trees (SPIHT) and the Rational Embedded Wavelet Image Coding (REWIC). SPIHT assigns priority based on the mean squared-error (MSE)...article 2004
- document
-
Díaz, I.F. (author), Epema, D. (author), de Jongh, J. (author), TNO Telecom (author)The nature of wireless multihop ad-hoc networks makes it a challenge to offer connections of an assured quality. In order to improve the performance of such networks, multipath routing in combination with Multiple Description Coding (MDC) has been proposed. By splitting up streams of multimedia traffic into several substreams (called...conference paper 2004
- document
-
Energieonderzoek Centrum Nederland (author), Schepers, J.G. (author)In this report an anlysis is made of measured load aerodynamic loadson wind turbine blades at yawed conditions. The measured loads are compared with results from the wind turbine design code PHATAS-IV. The aerodynamic model in PHATAS-IV is based on the blade element momentum model, with correction formula for yawed conditions. The measured data...report 2004
- document
-
van Erp, J.B.F. (author), van Veen, H.J. (author), TNO Technische Menskunde (author)A vibrotactile display, consisting ofeight vibrating elements or tactors mounted in a driver's seat, was tested in a driving simulator. Participants drove with visual, tactile and multimodal navigation displays through a built-up area. Workload and the reaction time to navigation messages were measured for normal and high workload conditions....article 2004
- document
-
Al-Sheikh, H. (author), Watson, A.J. (author), Lacey, G.A. (author), Punt, P.J. (author), MacKenzie, D.A. (author), Jeenes, D.J. (author), Pakula, T. (author), Penttilä, M. (author), Alcocer, M.J.C. (author), Archer, D.B. (author), TNO Voeding (author)We describe a new endoplasmic reticulum (ER)-associated stress response in the filamentous fungus Aspergillus niger. The inhibition of protein folding within the ER leads to cellular responses known collectively as the unfolded protein response (UPR) and we show that the selective transcriptional downregulation of the gene encoding glucoamylase,...article 2004
- document
-
TNO Industrial Technology (author), Schilthuizen, S.F. (author)The developments in tag, sensor and 'active' packaging technologies for intelligent functions and identification methods in food packaging, are discussed. Intelligent functions provide data about the authenticity of food products, and determine the quality of food or pharmaceutical product. Conductive polymers are used to create more reliable...article 2004
- document
-
TNO Bouw (author), Geurts, C.P.W. (author), van Staalduinen, P.C. (author), de Wit, M.S. (author)The most vulnerable parts of buildings with respect to wind loading are facades and roofs. Current standards on wind loading provide data to determine design loads for the elements in facades and roofs. These data are available for a limited number of simple building shapes. Up to now there is no common procedure to determine local loads for...article 2004
- document
-
Lubbers, J. (author), Hekkenberg, R.T. (author), Bezemer, R.A. (author), TNO Preventie en Gezondheid (author)Activities in the standardisation of medical ultrasonic imaging and monitoring devices have been undertaken to ensure the safe application and to provide the user with tools to perform risk-to-benefit analysis. Internationally, agreement has not been reached to implement a system based on a physical quantity such as temperature rise. Therefore,...article 2003
- document
-
Punt, P.J. (author), Drint-Kuijvenhoven, A. (author), Lokman, B.C. (author), Spencer, J.A. (author), Jeenes, D. (author), Archer, D.A. (author), van den Hondel, C.A.M.J.J. (author)We have characterized growth and protein processing characteristics of Aspergillus niger strains carrying a disrupted allele of the previously cloned and characterized kexB gene [Appl. Environ. Microbiol. 66 (2000) 363] encoding a furin-type endoprotease. Deletion of the single-copy gene confirms it to be non-essential but disruptant strains...article 2003