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Maasland, D.H.E. (author), van den Brandt, P.A. (author), Kremer, S.H.A. (author), Goldbohm, R.A. (author), Schouten, L.J. (author)Background: Prospective data on alcohol consumption, cigarette smoking and risk of head-neck cancer (HNC) subtypes, i.e. oral cavity cancer (OCC), oro-/hypopharyngeal cancer (OHPC), and laryngeal cancer (LC), are limited. We investigated these associations within the second largest prospective study on this topic so far, the Netherlands Cohort...article 2014
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Steevens, J. (author), Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author)Prospective epidemiologic data on vegetables and fruits consumption and risk of subtypes of esophageal and gastric cancer are sparse. We studied the association between vegetables and fruits consumption and risk of esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), gastric cardia adenocarcinoma (GCA) and gastric...article 2011
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Heinen, M.M. (author), Verhage, B.A.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)Background: To date, cigarette smoking is the most consistent risk factor for pancreatic cancer. We prospectively examined the role of active cigarette smoking, smoking cessation, and passive smoking as determinants for pancreatic cancer. Methods: The Netherlands Cohort Study consisted of 120,852 men and women who completed a baseline...article 2010
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Hille, E.T.M. (author), Dorrepaal, C. (author), Perenboom, R. (author), Gravenhorst, J.B. (author), Brand, R. (author), Verloove-Vanhorick, S.P. (author), TNO Kwaliteit van Leven (author)Objective: To assess social lifestyle, risk-taking behavior, and psychopathology in young adults born very preterm or with a very low birthweight. Study design: This study was part of the 19-year follow-up in a large ongoing collaborative study in the Netherlands (the POPS study) on the long-term outcome of prematurity and dysmaturity. 656...article 2008
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Hogervorst, J.G. (author), Schouten, L.J. (author), Konings, E.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)Background: Acrylamide, a probable human carcinogen, was recently detected in various heat-treated carbohydrate-rich foods. Epidemiologic studies on the relation with cancer have been few and largely negative. Objective: We aimed to prospectively examine the association between dietary acrylamide intake and renal cell, bladder, and prostate...article 2008
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de Pal van der-Bruin, K.M. (author), le Cessie, S. (author), Elsinga, J. (author), Jong de-Potjer, L.C. (author), van Haeringen, A. (author), Knuistingh Neven, A. (author), Verloove-Vanhorick, S.P. (author), Assendelft, P. (author), TNO Kwaliteit van Leven (author)The outcome of pregnancy can be influenced by several risk factors. Women who are informed about these risks during pre-conception counselling (PCC) have an opportunity to take preventive measures in time. Several studies have shown that high-risk populations have a high prevalence of such risk factors. However, prevalence in the general...article 2008
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Beelen, R. (author), Hoek, G. (author), van den Brandt, P.A. (author), Goldbohm, R.A. (author), Fischer, P. (author), Schouten, L.J. (author), Armstrong, B. (author), Brunekreef, B. (author), TNO Kwaliteit van Leven (author)Background: Most studies on the association between lung cancer and air pollution have investigated mortality. There have been few studies of lung cancer incidence. Methods: We used data from the ongoing Netherlands Cohort Study on Diet and Cancer for 114,378 subjects with follow-up from September 1986 to December 1997. Exposure to black smoke,...article 2008
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Loerbroks, A. (author), Schouten, L.J. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)Objective: To examine the association between alcohol consumption, cigarette smoking, and endometrial cancer. Methods: In 1986, the Netherlands Cohort Study was initiated. A self-administered questionnaire on dietary habits and other cancer risk factors was completed by 62,573 women. Follow-up for cancer was established by record linkage to the...article 2007
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Lanting, C. (author), Segaat, D. (author), Crone, M. (author), van Wouwe, K. (author), TNO Kwaliteit van Leven (author)Objective. To establish smoking prevalence of fertile-aged women; before and during pregnancy, and 6 months after delivery. Design. Cross-sectional. Method. Yearly surveys by questionnaires handed out during 2001-2003 to mothers visiting a Well Baby Clinic with infants aged 0-6 months. Results. Out of a total of 14,540 questionnaires, 9,133 (63%...article 2007
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TNO Kwaliteit van Leven (author), Verheijden, M.W. (author), Jans, M.P. (author), Hildebrandt, V.H. (author), Hopman-Rock, M. (author)Background: In recent years, many tailored lifestyle counseling programs have become available through the Internet. Previous research into such programs has shown selective enrollment of relatively healthy people. However, because of the known dose-response relationship between the intensity and frequency of counseling and the behavior change...article 2007
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Zeegers, M.P. (author), Selen, R.F.M. (author), Kleinjans, J.C.S. (author), Goldbohm, R.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)Objectives: N-nitroso compounds, endogenously formed from nitrate-derived nitrite, are suspected to be important bladder carcinogens. However, the association between nitrate exposure from food or drinking water and bladder cancer has not been substantially investigated in epidemiologic studies. Methods: We evaluated the associations between...article 2006
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van den Brandt, P.A. (author), Goldbohm, R.A. (author), TNO Kwaliteit van Leven (author)Diet has been hypothesized to play a role in the etiology of gastrointestinal cancer for a long time. Initially, strong evidence of such effects was found in retrospective epidemiological studies. Dietary habits, in particular those from the distant past, are difficult to measure, however. Results from recent, prospective and larger studies of...article 2006
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Weisglas-Kuperus, N. (author), Finken, M.J.J. (author), Keijzer-Veen, M.G. (author), Vrijlandt, E.J.L.E. (author), Hille, E.T.M. (author), de Groot, C.H. (author), Kloosterboer-Boerrigter, H. (author), den Ouden, A.L. (author), Rijpstra, A. (author), Verloove-Vanhorick, S.P. (author), Vogelaar, J.A. (author), Kok, J.H. (author), Ilsen, A. (author), van der Lans, M. (author), Boelen-van der Loo, W.J.C. (author), Lundqvist, T. (author), Heymans, H.S.A. (author), Duiverman, E.J. (author), Geven, W.B. (author), Duiverman, M.L. (author), Geven, L.I. (author), Mulder, A.L.M. (author), Gerver, A. (author), Kollée, L.A.A. (author), Reijmers, L. (author), Sonnemans, R. (author), Wit, J.M. (author), Dekker, F.W. (author), Wiesglas-Kuperus, N. (author), van der Heijden, A.J. (author), van Goudoever, J.B. (author), van Weissenbruch, M.M. (author), Cranendonk, A. (author), Delemarre-van de Waal, H.A. (author), de Groot, L. (author), Samsom, J.F. (author), de Vries, L.S. (author), Rademaker, K.J. (author), Moerman, E. (author), Voogsgeerd, M. (author), de Kleine, M.J.K. (author), Andriessen, P. (author), Dielissen-van Helvoirt, C.C.M. (author), Mohamed, I. (author), van Straaten, H.L.M. (author), Baerts, W. (author), Veneklaas Slots-Kloosterboer, G.W. (author), Tuller-Pikkemaat, E.M.J. (author), Ens-Dokkum, M.H. (author), van Steenbrugge, G.J. (author)Infants born very prematurely are at greater risk of neurosensory handicaps and developmental problems than are term born children. Premature birth, intrauterine growth retardation, and the combination of both, may also be risk factors for physical disease in adulthood. As this aspect has been little studied so far, we looked into its first...article 2006
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TNO Kwaliteit van Leven (author), van Dijk, B.A.C. (author), Schouten, L.J. (author), Oosterwijk, E. (author), Hulsbergen van de, (author), Kaa, C.A. (author), Kiemeney, L.A.L.M. (author), Goldbohm, R.A. (author), Schalken, J.A. (author), van den Brandt, P.A. (author)We investigated whether smoking is associated with mutations in the Von Hippel-Lindau (VHL) gene in 337 cases of sporadic renal cell carcinoma (RCC) among 120 852 people followed for 11.3 years; the findings suggest that smoking causes RCC independently of VHL gene mutations. © 2006 Cancer Research. Chemicals / CAS: adenine, 22177-51-1, 2922-28...article 2006
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Reijneveld, S.A. (author), Lanting, C.I. (author), Crone, M.R. (author), van Wouwe, J.P. (author)Aim: To examine the association of excessive infant crying with maternal smoking during and after pregnancy, paternal smoking, and smoking by other people in the living environment of the infant. Methods: We collected data on infant crying and smoking in a Dutch national sample of 5845 infants aged 0-3 mo (response 62.8%). We defined excessive...article 2005
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Lüchtenborg, M. (author), Weijenberg, M.P. (author), Kampman, E. (author), van Muijen, G.N. (author), Roemen, G.M.J.M. (author), Zeegers, M.P.A. (author), Goldbohm, R.A. (author), van't Veer, P. (author), de Goeij, A.F.P.M. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)The contribution of cigarette smoking to sporadic colorectal cancer may differ according to molecular aspects of the tumor or according to glutathione S-transferase M1 (GSTM1) or glutathione S-transferase T1 (GSTT1) genotype. In the prospective Netherlands Cohort Study on Diet and Cancer, adjusted incidence rate ratios for 1986-1993 were...article 2005
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Schouten, L.J. (author), van Dijk, B.A.C. (author), Oosterwijk, E. (author), van de Hulsbergen-Kaa, C.A. (author), Kiemeney, L.A.L.M. (author), Goldbohm, R.A. (author), Schalken, J.A. (author), van den Brandt, P.A. (author), TNO Kwaliteit van Leven (author)Objectives: Hypertension and/or antihypertensive medication are reported to be risk factors of renal cell carcinoma (RCC). We investigated whether these risk factors are associated with von Hippel-Lindau gene (VHL) mutations in RCC. Methods: The Netherlands Cohort Study on Diet and Cancer (NLCS) started in 1986 (n = 120 852 men and women) and...article 2005
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Agema, W.R.P. (author), de Maat, M.P.M. (author), Zwinderman, A.H. (author), Kastelein, J.J.P. (author), Rabelink, T.J. (author), van Boven, A.J. (author), Feskens, E.J.M. (author), Boer, J.M.A. (author), van der Wall, E.E. (author), Jukema, J.W. (author), Gaubius Instituut TNO (author)In the present study, we sought to evaluate the role of three polymorphisms in the ecNOS (endothelial constitutive nitric oxide synthase) gene in relation to the existence, severity and progression of CAD (coronary artery disease), MI (myocardial infarction) and the occurrence of ischaemia in a predominantly Caucasian population. Patients with...article 2004
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de Lange, A.H. (author), Taris, T.W. (author), Kompier, M.A.J. (author), Houtman, I.L.D. (author), Bongers, P.M. (author)This study addressed the methodological quality of longitudinal research examining R. Karasek and T. Theorell's (1990) demand-control-(support) model and reviewed the results of the best of this research. Five criteria for evaluating methodological quality were used: type of design, length of time lags, quality of measures, method of analysis,...article 2003
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Sierksma, A. (author), van der Gaag, M.S. (author), Grobbee, D.E. (author), Hendriks, H.F.J. (author)1. The present study investigated the acute and chronic effect of dinner with alcoholic beverages on serum nitric oxide (NO) metabolites, namely nitrate and nitrite (NOx), in 11 healthy, non-smoking middle-aged men. 2. In a randomized, diet-controlled, cross-over trial, subjects consumed dinner with four glasses of red wine, beer, spirits (Dutch...article 2003
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