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van Uffelen, J.G.Z. (author), Chin A Paw, M.J.M. (author), Klein, M. (author), van Mechelen, W. (author), Hopman-Rock, M. (author), TNO Kwaliteit van Leven (author)Background: Development of efficient methods for identifying subjects with Mild Cognitive Impairment (MCI) from the geneneral population is warranted, because these subjects represent an important group for (epidemiological) research purposes. Objectives: (1) To describe a two-step population screening for identifying adults with MCI from the...article 2007
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Barrell, Y. (author), Naus, H.W.L. (author), TNO Defensie en Veiligheid (author)Detection and localisation of hidden magnetic objects is studied. The concomitant disturbance of the earth magnetic field is exploited. Magnetic fields and or gradients are measured with a number of sensors. Two point models for magnetic fields are selected for the analysis: the magnetic dipole and its quadrupole extension. It is shown how to...article 2007
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Bos, J.E. (author), MacKinnon, S.N. (author), Patterson, A. (author), TNO Defensie en Veiligheid (author)Vehicle motion characteristics differ between air, road, and sea environments, both vestibularly and visually. Effects of vision on motion sickness have been studied before, though less systematically in a naval setting. It is hypothesized that appropriate visual information on self-motion is beneficial in a naval setting and that task...article 2005
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TNO Kwaliteit van Leven (author), van Sluijs, E.M.F. (author), van Poppel, M.N.M. (author), Twisk, J.W.R. (author), Brug, J. (author), van Mechelen, W. (author)PACE (Physician-based Assessment and Counseling for Exercise) is an individualized theory-based minimal intervention strategy aimed at the enhancement of regular physical activity. The aim of this study was to evaluate the effectiveness of a PACE intervention applied by general practitioners (GPs) on potential determinants of physical activity....article 2005
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Bemelmans, W.J.E. (author), Broer, J. (author), Hulshof, K.F.A.M. (author), Siero, F.W. (author), May, J.F. (author), Meyboom-de Jong, B. (author), TNO Voeding (author)Background: Treatment of persons at high risk for coronary heart disease (CHD) should include nutritional counselling, but little is known about the effects of different types of education. Methods: In a quasi-experimental study design the effects of a nutritional education programme (1st year: three group sessions by a dietitian; 2nd year: one...article 2004
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van de Bor, M. (author), den Ouden, L. (author), TNO Preventie en Gezondheid (author)Long-term sequelae of preterm birth have been studied extensively up until the age of 5 to 8 years. However, the cognitive development of adolescents born preterm has received limited attention. The objective of this study is to determine school performance in adolescents born very preterm. We have followed up a cohort of 484 infants born before...article 2004
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Graafmans, W.C. (author), Lips, P. (author), Wijlhuizen, G.J. (author), Pluijm, S.M. (author), Bouter, L.M. (author)Physical activity is usually considered as an important com0ponent of a healthy lifestyle, including a preventive effect on the risk of falls in the elderly. The relationship between physical activity and falls is complex: physical activity is a prerequisite to maintain neuromuscular functioning, necessary to keep balance and to react to a fall,...article 2003
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Engels, Y. (author), Verheijen, N. (author), Fleuren, M. (author), Mokkink, H. (author), Grol, R. (author)Objective: To study the effects of small group continuous quality improvement (CQI) on the clinical practice of midwives in the Netherlands. Design: Randomised pre-/post-test (balanced block). Intervention: The CQI groups were assigned to either the set of peer review topics including 'perineal repair' and 'artificial rupture of the membranes ...article 2003
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Schuller, A.A. (author), Willumsen, T. (author), Holst, D. (author)Epidemiological studies of the relationship between dental fear, use of dental services, and oral health in different age groups in a common population are scarce. Dental fear and its relationships are usually described in individuals with high dental fear only. The purposes of this study were to describe the prevalence of dental fear in the...article 2003
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TNO Preventie en Gezondheid (author), Schuller, A.A. (author), Kalsbeek, H. (author)The purpose of this study was to study the effect of professionally applied topical fluoride on oral health status at the population level in adolescents with low socio-economic status. Adolescents attending dental clinics where professional fluoride application was a routine procedure (high-fluoride group) were compared to adolescents from...article 2003
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van der Laan, W. (author), Molenaar, E. (author), Ronday, K. (author), Verheijen, J. (author), Breedveld, F. (author), Greenwald, R. (author), Dijkmans, B. (author), Tekoppele, J. (author), Gaubius instituut TNO (author)Objective. To investigate the effects of doxycycline on disease activity and joint destruction in patients with rheumatoid arthritis (RA). Methods. A 36 week double blind, placebo controlled crossover trial was conducted. Patients (n = 66) received 50 mg doxycycline or placebo twice a day during 12, 24, or 36 weeks. Patient assessments were...article 2001
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Kalsbeek, H. (author), Truin, G.J. (author), Poorterman, J.H.G. (author), van Rossum, G.M.J.M. (author), van Rijkom, H.M. (author), Verrips, G.H.W. (author)In 1995, a dental survey, similar to one carried out in 1983, was performed among persons aged 25-54 in the city of 's-Hertogenbosch, the Netherlands. Objective: To describe trends in adults periodontal health between 1983 and 1995. Methods: The participants were interviewed at home and clinically examined in a dental van. Results: Average...article 2000
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TNO Preventie en Gezondheid (author), Rietveld, M.J.H. (author), van der Valk, J.C. (author), Bongers, I.L. (author), Stroet, T.M. (author), Slagboom, P.E. (author), Boomsma, D.I. (author)This study reports on zygosity determination in twins of childhood age. Parents responded to questionnaire items dealing with twin similarity in physical characteristics anti frequency of mistaking one twin for another by parents, relatives and strangers. The accuracy of zygosity diagnosis was evaluated across twins aged 6, 8, and 10 and across...article 2000
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Verrips, G.H. (author), Hirasing, R.A. (author), Fekkes, M. (author), Vogels, T. (author), Verloove-Vanhorick, S.P. (author), van de Delemarre-Waal, H.A. (author), TNO Preventie en Gezondheid (author)The aim of the study was to test the hypothesis that daily administration of growth hormone using the Medi-Jector® results in fewer adverse psychological responses than needle injection with a multidose injection pen. The Medi-Jector is a needle-free injection device that can deliver growth hormone subcutaneously through jet injection. The group...article 1998
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Brugman, E. (author), Verrips, G.H. (author), Danz, M.J. (author), Kalsbeek, H. (author), TNO Preventie en Gezondheid (author)Objective: The aim of this study was to determine the extent to which dental prevention among Turkish parents differs from that among Moroccan parents in one of the large cities in the Netherlands. Design: Turkish and Moroccan mothers with a child of approximately six months old, who visited the well baby clinics in the Schilderswijk area of The...article 1998
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Schmand, B. (author), Hooijer, C. (author), Jonker, C. (author), Lindeboom, J. (author), Havekes, L.M. (author), Gaubius instituut TNO (author)Apolipoprotein E (ApoE) allele frequencies were examined in a population-based sample (n = 475; age range 65-84 years; Amsterdam Study of the Elderly). The relation of ApoE ε4 with dementia and with various types of late-life depression was studied. Depression was measured with the Geriatric Mental State schedule. Dementia was diagnosed by DSM...article 1998
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Haider, A.W. (author), Andreotti, F. (author), Hackett, D.R. (author), Tousoulis, D. (author), Kluft, C. (author), Maseri, A. (author), Davies, G.J. (author), Gaubius Instituut TNO (author)Objectives. This study investigated the influence of early spontaneous intermittent reperfusion on the extent of myocardial damage and its relation to endogenous hemostatic activity, Background. In the early phase of acute myocardial infarction coronary occlusion is often intermittent, even before thrombolytic therapy is administered. The...article 1995
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Verrips, G.H. (author), Kalsbeek, H. (author), van Woerkum, C.M. (author), Koelen, M. (author), Kok-Weimar, T.L. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)A previous study among Amsterdam 5-year-old children showed that on average, the older the child at the onset of toothbrushing and the less frequent the toothbrushing, the more life time caries experience it had. The aim of the present study was to assess correlates of these two caries risk factors, in four ethnic groups. A further aim was to...article 1994
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Verrips, G.H. (author), Frencken, J.E. (author), Kalsbeek, H. (author), Filedt Kok-Weimar, T.L. (author), Nederlands Instituut voor Praeventieve Gezondheidszorg TNO (author)This investigation was first, to assess the oral health of 11-year-old children in four ethnic groups in Amsterdam; second, to assess their dental behaviour and third, to identify potential determinants of frequency of toothbrushing. Representative samples of 97 Surinamese, 209 Moroccan, 128 Turkish and 102 Dutch children were examined orally...article 1993
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Kalsbeek, H. (author), Verrips, E. (author), Dirks, O.B. (author), TNO Preventie en Gezondheid (author)A study was executed to investigate the relation between the use of fluoride tablets by children in the age period 1.5-6 yr on the one hand and the caries experience at the age of 6 and 15 yr and the prevalence of fluorosis at the age of 15 yr on the other hand. The year of birth of the child, the motivation of the mother to engage in preventive...article 1992