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Perdijk, O. (author), Baarlen, P.V. (author), Fernandez-Gutierrez, M.M. (author), Brink, E.V. (author), Schuren, F.H.J. (author), Brugman, S. (author), Savelkoul, H.F.J. (author), Kleerebezem, M. (author), Neerven, R.J.J.V. (author)Human milk oligosaccharides (HMO) and prebiotic oligosaccharides are proposed to confer several health benefits to the infant. They shape the microbiota, have anti-inflammatory properties, and support epithelial barrier functioning. However, in order to select the best oligosaccharides for inclusion in infant formulas, there is a need to...article 2019
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Minnens, F. (author), Lucas Luijckx, N.B. (author), Verbeke, W. (author)One of the biggest challenges facing the food industry is assuring food integrity. Dealing with complex food integrity issues requires a multi-dimensional approach. Preventive actions and early reactive responses are key for the food supply chain. Information sharing could facilitate the detection and prevention of food integrity issues. This...article 2019
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Gart, E. (author), Souto Lima, E. (author), Schuren, F, (author), de Ruiter, C.G.F. (author), Attema, J. (author), Verschuren, L. (author), Keijer, J. (author), Salic, K. (author), Morrison, M.C. (author), Kleemann, R. (author)Development of non-alcoholic fatty liver disease (NAFLD) is linked to obesity, adipose tissue inflammation, and gut dysfunction, all of which depend on diet. So far, studies have mainly focused on diet-related fecal microbiota changes, but other compartments may be more informative on host health. We present a first systematic analysis of...article 2019
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Ehrler, V.C. (author), Seidel, S. (author), Lischke, A. (author), Davydenko, I. (author), Dobers, K. (author), Lewis, A. (author), Val, S. (author), Luzzini, D. (author)Standardization of emission calculation is progressing swiftly in order to support the improvement of the sustainability of transport chains. Using the GLEC Framework v1.0 as a starting point, this research maps out, which further gaps need to be addressed for ensuring seamless coverage at a meaningful accuracy of such a calculation. The...conference paper 2018
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Hofman, W.J. (author), Spek, J.C. (author), van Ommeren, C.R. (author)Improved situational awareness, also known as supply chain visibility, contributes to better decisions with the ability to synchronize processes and reduce costs. It requires data sharing of for instance positions and Estimated Time of Arrival (ETA) of transport means. Blockchain technology could be a means to support data sharing, due to its...conference paper 2018
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Tukker, A. (author), de Koning, A. (author), Owen, A. (author), Lutter, S. (author), Bruckner, M. (author), Giljum, S. (author), Stadler, K. (author), Wood, R. (author), Hoekstra, R. (author)Global multiregional input-output databases (GMRIOs) became the standard tool for tracking environmental impacts through global supply chains. To date, several GMRIOs are available, but the numerical results differ. This paper considers how GMRIOs can be made more robust and authoritative. We show that GMRIOs need detail in environmentally...article 2018
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de Jong, G.A.H. (author), Jayasena, S. (author), Johnson, P. (author), Marsh, J. (author), Apostolovic, D. (author), van Hage, M. (author), Nordlee, J. (author), Baumert, J. (author), Taylor, S.L. (author), Roucairol, C. (author), de Jongh, H. (author), Koppelman, S.J. (author)The 2S albumin Ara h 6 is one of the most important peanut allergens. A post-translationally cleaved Ara h 6 (pAra h 6) was purified from Virginia type peanuts, and the cleavage site was mapped using high-resolution mass spectrometry. Compared to intact Ara h 6, pAra h 6 lacks a 5-amino acid stretch, resembling amino acids 43-47 (UniProt...article 2018
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Remels, A.H.V. (author), Derks, W.J.A. (author), Cillero-Pastor, B. (author), Verhees, K.J.P. (author), Kelders, M.C. (author), Heggermont, W. (author), Carai, P. (author), Summer, G. (author), Ellis, S.R. (author), de Theije, C.C. (author), Heeren, R.M.A. (author), Heymans, S. (author), Papageorgiou, A.P. (author), van Bilsen, M. (author)Acute viral myocarditis (VM), characterised by leukocyte infiltration and dysfunction of the heart, is an important cause of sudden cardiac death in young adults. Unfortunately, to date, the pathological mechanisms underlying cardiac failure in VM remain incompletely understood. In the current study, we investigated if acute VM leads to cardiac...article 2018
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Savikhin, V. (author), Babics, M. (author), Neophytou, M. (author), Liu, S. (author), Oosterhout, S.D. (author), Yan, H. (author), Gu, X. (author), Beaujuge, P.M. (author), Toney, M.F. (author)Efficiencies of organic photovoltaic (OPV) devices have been steadily climbing, but there is still a prominent gap in understanding the relationship between fabrication and performance. Side chain substitution is one processing parameter that can change OPV device efficiency considerably, primarily because of variations in morphology. In this...article 2018
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Dalmolen, S. (author), Bastiaansen, H.J.M. (author), Moonen, H. (author), Hofman, W.J. (author), Punter, L.M. (author), Cornelisse, E. (author)In support of the trend towards ever more complex supply chain collaboration for the Physical Internet, a trusted, multi-tenant (and interoperable) data sharing infrastructure has to be enabled. Trust is a condition sine qua non organizations may not be prepared to share potentially competitive sensitive information. As such, trust has to be an...conference paper 2018
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van Wegberg, R.S. (author), Klievink, A.J. (author), van Eeten, M.J.G. (author)Fraud with online payment services is an ongoing problem, with significant financial-economic and societal impact. One of the main modus operandi is financial malware that compromises consumer and corporate devices, thereby potentially undermining the security of critical financial systems. Recent research into the underground economy has shown...article 2017
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Dragt, R.C. (author), Allaix, D.L. (author), Maljaars, J. (author), Tuitman, J.T. (author), Salman, Y. (author), Otheguy, M.E. (author)Fatigue is one of the main design drivers for offshore wind substructures. Using Fracture Mechanics methods, load sequence effects such as crack growth retardation due to large load peaks can be included in the fatigue damage estimation. Due to the sequence dependency, a method is required that represents the sequences of loads in the design or...conference paper 2017
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Hereijgers, K. (author), Silvas, E. (author), Hofman, T. (author), Steinbuch, M. (author)Creating a driving cycle (DC) for the design and validation of new vehicles is an important step that will influence the efficiency, functionality and performance of the final systems. In this work, a DC synthesis method is introduced, based on multi-dimensional Markov Chain, where both the velocity and road slope are investigated. Particularly,...article 2017
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Fluitman, K.S. (author), de Clercq, N.C. (author), Keijser, B.J.F. (author), Visser, M. (author), Nieuwdorp, M. (author), Ijzerman, R.G. (author)Introduction: Malnutrition refers to both over- and undernutrition and results from a disruption in energy balance. It affects one in three people worldwide and is associated with increased morbidity and mortality. The intestinal microbiota represents a newly identified factor that might contribute to the development of malnutrition, as it...article 2017
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Eickhoff, C. (author), Brown, A. (author), Neele, F. (author)The IMPACTS project has the objective to develop the knowledge base of CO2 quality required for establishing norms and regulations to ensure safe and reliable design, construction and operation of CO2 pipelines and injection equipment, and safe long-term geological storage of CO2. More specifically for this paper, the project sets out to reveal...conference paper 2017
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Neele, F. (author), Koornneef, J. (author), Jakobsen, J.P. (author), Brunsvold, A. (author), Eickhoff, C. (author)There is a need to gather new knowledge on the fundamental properties of CO2 mixtures with impurities and their impact on the chain integrity and economics of Carbon Capture & Storage (CCS) chains. One of the main results from the FP7 IMPACTS project is the IMPACTS toolbox, which comprises new experimental data, thermodynamic reference models...conference paper 2017
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Tuma, M. (author), Rorbech, V. (author), Prior, M. (author), Igel, C. (author)We designed and jointly optimized an integrated signal processing chain for detection and classification of long-range passive-acoustic underwater signals recorded by the global geophysical monitoring network of the Comprehensive Nuclear-Test-Ban Treaty Organization. Starting at the level of raw waveform data, a processing chain of signal...article 2016
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- Verhoosel, J.P.C. (author), van Bekkum, M.A. (author), Verwaart, T. (author) conference paper 2016
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Reisch, L.A. (author), Cohen, M.J. (author), Thøgersen, J.B. (author), Tukker, A. (author)While the field of sustainable consumption research is relatively young, it has already attracted scholars from all corners of the social sciences. The time has come to identify a new research agenda as trends in sustainable consumption research seem to suggest the dawning of a new phase. Not only does research need to be guided, but sustainable...article 2016
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Zhang, X. (author), Noel, N. (author), Ferrari, G. (author), Hoogland, M.G. (author)Failures of mooring lines on floating production, storage and offloading systems (FPSOs) raise concern to the offshore industry. Localized corrosion of mooring chain is regarded as one of main failure mechanisms. The project of Localized Mooring Chain Corrosion (LMCC) is aiming at studying the mechanism of local corrosion on mooring chain steel...conference paper 2016