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Linders, Y.F.M. (author), Lentz, L.R. (author), Blom, W.M. (author), Michelsen-Huisman, A. (author), Strikwerda, J. (author), van Dijk, L.M. (author), Knulst, A.C. (author), Houben, G.F. (author), van Os-Medendorp, H. (author), Holleman, B.C. (author)While there are EU laws for priority allergenic ingredients information on food product packaging, there is no legislation about Precautionary Allergen Labelling (PAL) for unintended allergen presence (UAP). As a result, PAL is used in different ways by different manufacturers and retailers, which hampers consumers’ interpretation of the...article 2023
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Fransman, W. (author), Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author)Objectives: Within the chemical legislation, REACH was implemented in order to improve safe working conditions with hazardous substances. Literature and real-life experiences by those concerned have shown that there are still gaps with a need for improved risk communication. This study elaborated on how information provided by REACH is...article 2023
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Gayban, A.J.B. (author), Souza, L.A.C. (author), Cooper, S.G. (author), Regalado, E. (author), Kleemann, R. (author), Earley, Y.F. (author)Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum of liver damage directly related to diabetes, obesity, and metabolic syndrome. The (pro)renin receptor (PRR) has recently been demonstrated to play a role in glucose and lipid metabolism. Here, we test the hypothesis that the PRR regulates the development of diet-induced hepatic...article 2023
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Lindner, C. (author), Looijesteijn, E. (author), van Dijck, H. (author), Bovee-Oudenhoven, I. (author), Heerikhuisen, M. (author), van den Broek, T.J. (author), Marzorati, M. (author), Triantis, V. (author), Nauta, A. (author)The objective of the current study was to evaluate the potential of 2′-FL and GOS, individually and combined, in beneficially modulating the microbial composition of infant and toddler (12–18 months) feces using the micro-Matrix bioreactor. In addition, the impacts of GOS and 2′-FL, individually and combined, on the outgrowth of fecal...article 2023
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Ding, S. (author), Tukker, A. (author), Ward, H. (author)In recent years, circular business models (CBM) have become an inevitable requirement to foster improvements in environmental performance. However, the current literature rarely discusses the link between Internet of Things (IoT) and CBM. This paper first identifies four IoT capabilities including monitoring, tracking, optimization and design...article 2023
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Tous, L. (author), Govaert, J. (author), Harrison, S. (author), Carrière, C. (author), Barth, V. (author), Giglia, V. (author), Buchholz, F. (author), Chen, N. (author), Halm, A. (author), Faes, A. (author), Nogay, G. (author), Quest, H. (author), Roessler, T. (author), Fellmeth, T. (author), Reinwand, D. (author), Stolzenburg, H. (author), Schindler, F. (author), Mittag, M. (author), Morlier, A. (author), Bokalic, M. (author), Brecl, K. (author), Kikelj, M. (author), Topic, M. (author), Kester, J.C.P. (author), Wendlandt, S. (author), Galiazzo, M. (author), Voltan, A. (author), Galbiati, G. (author), Ortiga, M.E. (author), Torregrosa, F. (author), Grimm, M. (author), Denafas, J. (author), Radavicius, T. (author), Lukinskas, P. (author), Savisalo, T. (author), Regrettier, T. (author), Gordon, I. (author)The EU crystalline silicon (c-Si) PV manufacturing industry has faced strong foreign competition in the last decade. To strive in this competitive environment and differentiate itself from the competition, the EU c-Si PV manufacturing industry needs to (1) focus on highly performing c-Si PV technologies, (2) include sustainability by design, and...article 2023
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Zhang, X. (author), Noel-Hermes, N. (author), Ferrari, G. (author), Hoogeland, M.G. (author)Corrosion of mooring chains is regarded as one of main threats to the offshore mooring systems. Localized corrosion is even more dangerous than uniform corrosion because it may not show significant mass loss but it can cause stress concentration and initiate cracks under force, leading to accelerated degradation of mooring chains. Localized...article 2022
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Yuan, R. (author), Rodrigues, J.F.D. (author), Tukker, A. (author), Behrens, P. (author)Projections of future emissions based on current trends are vital to assess the performance of mitigation efforts and to devise mitigation strategies. However, previous studies are uncertain how the persistence and convergence of mitigation efforts may impact future trajectories from the consumption perspective. Here we assume regional...article 2022
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A Framework on Centralised to Decentralised Logistics Control Structures Applied in Two Case StudiesHopman, M. (author), Fransen, R. (author), van Meijeren, J. (author), Zubin, I. (author)Developments on digitalisation and automation in transport and logistics create new possibilities in the organisation of supply chains. New technologies can disrupt existing control structures, establish new forms of control and improve the efficiency and flexibility of operations. This paper provides a framework to analyse the trade-offs and...conference paper 2022
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- Lennartz, J. (author), Toxopeus, M.E. (author), Meulen, J.V.D. (author) conference paper 2022
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Davydenko, I. (author), Hopman, M. (author), Fransen, R.W. (author), Harmsen, J. (author)There is a strong need to reduce emissions from transport and logistics. Electrificationand use of greener energy carriers and fuels provide a ready way to reduce emissions, but thesetechnologies are generally more expensive than the conventional ones they are replacing. Fortunately,some shippers are willing to pay the extra cost to ship their...article 2022
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Remington, B.C. (author), Baumert, J. (author), Blom, W.M. (author), Bucchini, L. (author), Buck, N. (author), Crevel, R. (author), de Mooij, F. (author), Flanagan, S. (author), Hindley, J. (author), Javed, B. (author), Stavropoulou, D.A. (author), van den Dungen, M.W. (author), van Ravenhorst, M. (author), Wang, S. (author), Walker, M. (author)Quantitative risk assessment (QRA) for allergens exists in many different forms with different requirements placed on the risk assessor depending on the question that needs to be answered. An electronic workshop held in October 2020 and comprising representatives from a wide range of food allergy and allergen stakeholder groups identified that a...article 2022
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Bauer, C. (author), Treyer, K. (author), Antonini, C. (author), Bergerson, J. (author), Gazzani, M. (author), Gencer, E. (author), Gibbins, J. (author), Mazzotti, M. (author), McCoy, S.T. (author), McKenna, R. (author), Pietzcker, R. (author), Ravikumar, A.P. (author), Romano, M.C. (author), Ueckerdt, F. (author), Vente, J. (author), van der Spek, M. (author)Natural gas based hydrogen production with carbon capture and storage is referred to as blue hydrogen. If substantial amounts of CO2 from natural gas reforming are captured and permanently stored, such hydrogen could be a low-carbon energy carrier. However, recent research raises questions about the effective climate impacts of blue hydrogen...article 2022
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Somers, G. (author), Hendrickx, R. (author), Nooijen, F. (author), van Dijk, C. (author), Vos, M. (author), Hulsegge, G. (author)Sharehouse maakt deel uit van het onderzoeksprogramma Duurzame Living Labs dat (mede)gefinancierd is door de Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO), Ministerie Infrastructuur & Waterstaat, Nationaal Regieorgaan Praktijkgericht Onderzoek (SIA) en de Topsector Logistiek. De NWO dossiernummer is 439.18.452. TKI Dinalog houdt...article 2022
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Grinberg, M. (author), Stöber, R.M. (author), Edlund, K. (author), Rempel, E. (author), Godoy, P. (author), Reif, R. (author), Widera, A. (author), Madjar, K. (author), Schmidt-Heck, W. (author), Marchan, R. (author), Sachinidis, A. (author), Spitkovsky, D. (author), Hescheler, J. (author), Carmo, H. (author), Arbo, M.D. (author), van de Water, B. (author), Wink, S. (author), Vinken, M. (author), Rogiers, V. (author), Escher, S. (author), Hardy, B. (author), Mitic, D. (author), Myatt, G. (author), Waldmann, T. (author), Mardinoglu, A. (author), Damm, G. (author), Seehofer, D. (author), Nüssler, A. (author), Weiss, T.S. (author), Oberemm, A. (author), Lampen, A. (author), Schaap, M.M. (author), Luijten, M. (author), van Steeg, H. (author), Thasler, W.E. (author), Kleinjans, J.C.S. (author), Stierum, R.H. (author), Leist, M. (author), Rahnenführer, J. (author), Hengstler, J.G. (author)Correction to: Arch Toxicol (2014) 88:2261–2287 https://doi.org/10.1007/s00204-014-1400-x.article 2022
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Gart, E. (author), van Duyvenvoorde, W. (author), Caspers, M.P.M. (author), van Trigt, N. (author), Snabel, J. (author), Menke, A. (author), Keijer, J. (author), Salic, K. (author), Morrison, M.C. (author), Kleemann, R. (author)Non-alcoholic steatohepatitis (NASH) is associated with a disturbed metabolism in liver, insulin resistance, and excessive accumulation of ectopic fat. Branched-chain amino acids (BCAAs) may beneficially modulate hepatic lipids, however, it remains unclear whether individual BCAAs can attenuate already established NASH and associated oxidative...article 2022
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Otten, W. (author), Marquart, H. (author), Preuhs, K. (author), Willemsen, J. (author), Boumann, H. (author), Gerritsen, R. (author), Fransman, W. (author)Presently, there is a lack of knowledge on the effectiveness of the information exchange on safe use conditions up and down the supply chain. The aim of the present research project CEFIC LRI B23 was to provide a substantial contribution to the knowledge needed to optimize information exchange on safe use conditions, specifically under REACH....report 2022
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Zhang, B. (author), Guo, C. (author), Lin, T. (author), Faaij, A.P.C. (author)Environmental factors, including greenhouse gas (GHG) emissions and soil organic carbon (SOC), should be considered when building a sustainable biofuel supply chain. This work developed a three-step optimization approach integrating a geographical information system-based mixed-integer linear programming model to economically optimize the...article 2022
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Wieclawska, S.M. (author), van Leeuwen, A.J.F. (author)The Netherlands currently imports and partially produces coal, crude oil and natural gas in order to provide for electricity,heat, fuel and chemicals. The coal, crude oil and natural gas provide the molecules (carbon, nitrogen, hydrogen and oxygen) which can be turned into the desired service (electricity, heat) or molecule (fuel, chemicals). In...report 2022
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Hajonides van der Meulen, T.C. (author), Sariç, M. (author), Tyraskis, I. (author), van Leeuwen, A.J.F. (author), Verstraten, P. (author)One of the central transitions that is part of our global efforts to transition to at least net zero, are the energy transition and the raw material transition. The energy transition describes the change in the global primary energy supply and demand from fossil-based energy to renewable energy. The raw material transition, or the transition...report 2022