Searched for: subject:"Cancer"
(1 - 20 of 272)

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Hamdiui, N. (author), Marchena, E. (author), Stein, M.L. (author), van Steenbergen, J.E. (author), Crutzen, R. (author), van Keulen, H.M. (author), Reis, R. (author), van den Muijsenbergh, M.E.T.C. (author), Timen, A. (author)
Objectives: Whether the lower Dutch cervical cancer (CC) screening participation of Turkish- and Moroccan-Dutch women is based on informed decision-making is unknown. Our aim was to explore how and why Turkish- and Moroccan-Dutch women decide to participate or not in the current Dutch CC screening programme as well as to learn their perceptions...
article 2021
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Bugter, O. (author), Li, Y. (author), Wolters, A.H.G. (author), Agrawal, V. (author), Dravid, A. (author), Chang, A. (author), Hardillo, J. (author), Giepmans, B.N.G. (author), Baatenburg de Jong, R.J. (author), Amelink, A. (author), Backman, V. (author), Robinson, D.J. (author)
article 2021
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Heusinkveld, H. (author), Braakhuis, H. (author), Gommans, R. (author), Botham, P. (author), Corvaro, M. (author), van der Laan, J.W. (author), Lewis, D. (author), Madia, F. (author), Manou, I. (author), Schorsch, F. (author), Wolterink, G. (author), Woutersen, R. (author), Corvi, R. (author), Mehta, J. (author), Luijten, M. (author)
Chemical substances are subjected to assessment of genotoxic and carcinogenic effects before being marketed to protect man and the environment from health risks. For agrochemicals, the long-term rodent carcinogenicity study is currently required from a regulatory perspective. Although it is the current mainstay for the detection of nongenotoxic...
article 2020
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Sewell, F. (author), Strupp, C. (author), van der Laan, J.W. (author), Wolf, D.C. (author), Wolterink, G. (author), Woutersen, R. (author), Zvonar, Z. (author), Heusinkveld, H. (author), Braakhuis, H. (author)
Currently the only methods for non-genotoxic carcinogenic hazard assessment accepted by most regulatory authorities are lifetime carcinogenicity studies. However, these involve the use of large numbers of animals and the relevance of their predictive power and results has been scientifically challenged. With increased availability of innovative...
article 2020
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Pot, M. (author), van Keulen, H. (author), Paulussen, T. (author), Otten, W. (author), van Steenbergen, J. (author), Ruiter, R. (author)
Background: In order to promote HPV-vaccination acceptability among mothers of invited girls, we developed a web-based, tailored intervention. This study reports on an experimental pretest for the component of this intervention targeting mothers’ perceptions of their daughters’ susceptibility towards HPV-related risk factors. Statistical versus...
article 2019
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Amirabadi, H. Eslami (author), Tuerlings, M. (author), Hollestelle, A. (author), SahebAli, S. (author), Luttge, R. (author), van Donkelaar, C.C. (author), Martens, J.W.M. (author), den Toonder, J.M.J. (author)
E-cadherin is a cell-cell adhesion protein that plays a prominent role in cancer invasion. Inactivation of E-cadherin in breast cancer can arise from gene promoter hypermethylation or genetic mutation. Depending on their E-cadherin status, breast cancer cells adopt different morphologies with distinct invasion modes. The tumor microenvironment ...
article 2019
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Thomas, G. (author), Tahir, M.R. (author), Bongers, B.C. (author), Kallen, V. (author), Slooter, G.D. (author), van Meeteren, N.L. (author)
BACKGROUND: Although prehabilitation programmes for patients undergoing major intra-abdominal cancer surgery have been shown to improve pre-operative physical fitness, the conclusions regarding any postoperative benefits are inconsistent. OBJECTIVES: The aim of this study was to evaluate the content of and the outcome measures used in studies of...
article 2019
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Fransman, W. (author)
public lecture 2019
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Weinmayr, G. (author), Pedersen, M. (author), Stafoggia, M. (author), Andersen, Z.J. (author), Galassi, C. (author), Munkenast, J. (author), Jaensch, A. (author), Oftedal, B. (author), Krog, N.H. (author), Aamodt, G. (author), Pyko, A. (author), Pershagen, G. (author), Korek, M. (author), de Faire, U. (author), Pedersen, N.L. (author), Ostenson, C.G. (author), Rizzuto, D. (author), Sørensen, M. (author), Tjønneland, A. (author), Bueno-de-Mesquita, B. (author), Vermeulen, R. (author), Eeftens, M. (author), Concin, H. (author), Lang, A. (author), Wang, M. (author), Tsai, M.Y. (author), Ricceri, F. (author), Sacerdote, C. (author), Ranzi, A. (author), Cesaroni, G. (author), Forastiere, F. (author), de Hoogh, K. (author), Beelen, R. (author), Vineis, P. (author), Kooter, I. (author), Sokhi, R. (author), Brunekreef, B. (author), Hoek, G. (author), Raaschou-Nielsen, O. (author), Nagel, G. (author)
Introduction: Previous analysis from the large European multicentre ESCAPE study showed an association of ambient particulate matter <2.5 μm (PM2.5) air pollution exposure at residence with the incidence of gastric cancer. It is unclear which components of PM are most relevant for gastric and also upper aerodigestive tract (UADT) cancer and some...
article 2018
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Andersen, Z.J. (author), Pedersen, M. (author), Weinmayr, G. (author), Stafoggia, M. (author), Galassi, C. (author), Jørgensen, J.T. (author), Sommar, J.N. (author), Forsberg, B. (author), Olsson, D. (author), Oftedal, B. (author), Aasvang, G.M. (author), Schwarze, P. (author), Pyko, A. (author), Pershagen, G. (author), Korek, M. (author), Faire, U.D. (author), Östenson, C.G. (author), Fratiglioni, L. (author), Eriksen, K.T. (author), Poulsen, A.H. (author), Tjønneland, A. (author), Braüner, E.V. (author), Peeters, P.H. (author), Bueno-De-Mesquita, B. (author), Jaensch, A. (author), Nagel, G. (author), Lang, A. (author), Wang, M. (author), Tsai, M.Y. (author), Grioni, S. (author), Marcon, A. (author), Krogh, V. (author), Ricceri, F. (author), Sacerdote, C. (author), Migliore, E. (author), Vermeulen, R. (author), Sokhi, R. (author), Keuken, M. (author), de Hoogh, K. (author), Beelen, R. (author), Vineis, P. (author), Cesaroni, G. (author), Brunekreef, B. (author), Hoek, G. (author), Raaschou-Nielsen, O. (author)
Background. Epidemiological evidence on the association between ambient air pollution and brain tumor risk is sparse and inconsistent. Methods. In 12 cohorts from 6 European countries, individual estimates of annual mean air pollution levels at the baseline residence were estimated by standardized land-use regression models developed within the...
article 2018
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van Groen, B.D. (author), van de Steeg, E. (author), Mooij, M.G. (author), van Lipzig, M.M.H. (author), de Koning, B.A.E. (author), Verdijk, R.M. (author), Wortelboer, H.M. (author), Gaedigk, R. (author), Bi, C. (author), Leeder, S. (author), van Schaik, R.H.N. (author), van Rosmalen, J. (author), Tibboel, D. (author), Vaes, W.H. (author), de Wildt, S.N. (author)
Background Hepatic membrane transporters are involved in the transport of many endogenous and exogenous compounds, including drugs. We aimed to study the relation of age with absolute transporter protein expression in a cohort of 62 mainly fetus and newborn samples. Methods Protein expressions of BCRP, BSEP, GLUT1, MCT1, MDR1, MRP1, MRP2, MRP3,...
article 2018
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Fransman, W. (author), Pronk, A. (author), Schelvis, R.M.C. (author), Moons, A.A.M. (author)
Although work is good for you, it can actually be bad for your health, too. Poor working conditions are responsible for 5% of the total disease burden1, a percentage that is the same as the figure for the adverse health effects resulting from an unhealthy environment or obesity. After smoking, these three factors are responsible for the major...
other 2017
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Pot, M. (author), van Keulen, H.M. (author), Ruiter, R.A.C. (author), Eekhout, I. (author), Mollema, L. (author), Paulussen, T.W.G.M. (author)
Background In the Netherlands, HPV-vaccination uptake among 12-year-old girls remains to be lower (61% in 2016) than expected. The present study is about 1) replicating the extent to which social-psychological determinants found in earlier cross-sectional studies explain HPV-vaccination intention, and 2) testing whether HPV-vaccination intention...
article 2017
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Wu, K. (author), Spiegelman, D. (author), Hou, T. (author), Albanes, D. (author), Allen, N.E. (author), Berndt, S.I. (author), van den Brandt, P.A. (author), Giles, G.G. (author), Giovannucci, E. (author), Goldbohm, R.A. (author), Goodman, G.G. (author), Goodman, P.J. (author), Håkansson, N. (author), Inoue, M. (author), Key, T.J. (author), Kolonel, L.N. (author), Männistö, S. (author), McCullough, M.L. (author), Neuhouser, M.L. (author), Park, Y. (author), Platz, E.A. (author), Schenk, J.M. (author), Sinha, R. (author), Stampfer, M.J. (author), Stevens, V.L. (author), Tsugane, S. (author), Visvanathan, K. (author), Wilkens, L.R. (author), Wolk, A. (author), Ziegler, R.G. (author), Smith-Warner, S.A. (author)
Reports relating meat intake to prostate cancer risk are inconsistent. Associations between these dietary factors and prostate cancer were examined in a consortium of 15 cohort studies. During follow-up, 52,683 incident prostate cancer cases, including 4,924 advanced cases, were identified among 842,149 men. Cox proportional hazard models were...
article 2016
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Heikkila, K. (author), Nyberg, S.T. (author), Madsen, I.E. (author), de Vroome, E. (author), Alfredsson, L. (author), Bjorner, J.B. (author), Borritz, M. (author), Burr, H. (author), Erbel, R. (author), Ferrie, J.E. (author), Fransson, E. (author), Geuskens, G.A. (author), Hooftman, W.E. (author), Houtman, I.L. (author), Jöckel, K.H. (author), Knutsson, A. (author), Koskenvuo, M. (author), Lunau, T. (author), Nielsen, M.L. (author), Nordin, M. (author), Oksanen, T. (author), Pejtersen, J.H. (author), Pentti, J. (author), Shipley, M.J. (author), Steptoe, A. (author), Suominen, S.B. (author), Theorell, T. (author), Vahtera, J. (author), Westerholm, P.J.M. (author), Westerlund, H. (author), Dragano, N. (author), Rugulies, R. (author), Kawachi, I. (author), Batty, G.D. (author), Singh-Manoux, A. (author), Virtanen, M. (author), Kivimäki, M. (author)
Background: Working longer than the maximum recommended hours is associated with an increased risk of cardiovascular disease, but the relationship of excess working hours with incident cancer is unclear. Methods: This multi-cohort study examined the association between working hours and cancer risk in 116 462 men and women who were free of...
article 2016
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de Marchi, T. (author), Braakman, R.B.H. (author), Stingl, C. (author), van Duijn, M.M. (author), Smid, M. (author), Foekens, J.A. (author), Luider, T.M. (author), Martens, J.W.M. (author), Umar, A. (author)
article 2016
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Velikova, M. (author), Dutra, I. (author), Burnside, E.S. (author)
The development and use of computerized decision-support systems in the domain of breast cancer has the potential to facilitate the early detection of disease
bookPart 2015
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Maasland, D.H.E. (author), van den Brandt, P.A. (author), Kremer, B. (author), Goldbohm, R.A. (author), Schouten, L.J. (author)
There is limited prospective data on the relationship between consumption of vegetables and fruits and the risk of head-neck cancer (HNC) subtypes [i.e., oral cavity cancer (OCC), oro-/hypopharyngeal cancer (OHPC) and laryngeal cancer (LC)]. Therefore, we investigated these associations within the Netherlands Cohort Study, in which 120,852...
article 2015
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Grinberg, M. (author), Stöber, R.M. (author), Edlund, K. (author), Rempel, E. (author), Godoy, P. (author), Reif, R. (author), Widera, A. (author), Madjar, K. (author), Schmidt-Heck, W. (author), Marchan, R. (author), Sachinidis, A. (author), Spitkovsky, D. (author), Hescheler, J. (author), Carmo, H. (author), Arbo, M.D. (author), van de Water, B. (author), Wink, S. (author), Vinken, M. (author), Rogiers, V. (author), Escher, S. (author), Hardy, B. (author), Mitic, D. (author), Myatt, G. (author), Waldmann, T. (author), Mardinoglu, A. (author), Damm, G. (author), Seehofer, D. (author), Nüssler, A. (author), Weiss, T.S. (author), Oberemm, A. (author), Lampen, A. (author), Schaap, M.M. (author), Luijten, M. (author), van Steeg, H. (author), Thasler, W.E. (author), Kleinjans, J.C.S. (author), Stierum, R.H. (author), Leist, M. (author), Rahnenführer, J. (author), Hengstler, J.G. (author)
A long-term goal of numerous research projects is to identify biomarkers for in vitro systems predicting toxicity in vivo. Often, transcriptomics data are used to identify candidates for further evaluation. However, a systematic directory summarizing key features of chemically influenced genes in human hepatocytes is not yet available. To bridge...
article 2014
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Offermans, N.S.M. (author), Vermeulen, R. (author), Burdorf, A. (author), Goldbohm, R.A. (author), Keszei, A.P. (author), Peters, S. (author), Kauppinen, T. (author), Kromhout, H. (author), van den Brandt, P.A. (author)
The evidence for an association between occupational asbestos exposure and esophageal, gastric and colorectal cancer is limited. We studied this association specifically addressing risk differences between relatively low and high exposure, risk associated with cancer subtypes, the influence of potential confounders and the interaction between...
article 2014
Searched for: subject:"Cancer"
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