Searched for: subject%3A%22Calcium%22
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Nelson, G. (author), Kozlova-Zwinderman, O. (author), Collis, A.J. (author), Knight, M.R. (author), Fincham, J.R.S. (author), Stanger, C.P. (author), Renwick, A. (author), Hessing, J.G.M. (author), Punt, P.J. (author), van den Hondel, C.A.M.J.J. (author), Read, N.D. (author), TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author)
Calcium signalling is little understood in filamentous fungi largely because easy and routine methods for calcium measurement in living hyphae have previously been unavailable. We have developed the recombinant aequorin method for this purpose. High levels of aequorin expression were obtained in Neurospora crassa, Aspergillus niger and...
article 2004
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Nieuwenhuizen, W.F. (author), Dekker, H.L. (author), de Koning, L.J. (author), Gröneveld, T. (author), de Koster, C.G. (author), de Jong, G.A.H. (author)
The molecular structures determine the physical properties of milk proteins and are important for the texture of many dairy-based foods. Bovine α-lactalbumin (α-LA) is a globular 123 amino acid Ca2+ binding milk protein. Modification with microbial Ca2+ independent transglutaminase (MTGase) was used to modify lysines and glutamines in holo and...
article 2003
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van Doren, H.A. (author), Slaghek, T.M. (author), Timmermans, J.W. (author), Besemer, A.C. (author), Jetten, J.M. (author), TNO Voeding (author)
article 2003
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Boelsma, E. (author), van de Vijver, L.P.L. (author), Goldbohm, R.A. (author), Klöpping-Ketelaars, I.A.A. (author), Hendriks, H.F.J. (author), Roza, L. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Background: Nutritional factors exert promising actions on the skin, but only scant information is available on the modulating effects of physiologic concentrations of nutrients on the skin condition of humans. Objective: The objective was to evaluate whether nutrient concentrations in serum and diet are associated with the skin condition of...
article 2003
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Delsing, D.J.M. (author), Jukema, J.W. (author), van de Wiel, M.A. (author), Emeis, J.J. (author), van der Laarse, A. (author), Havekes, L.M. (author), Princen, H.M.G. (author), Gaubius Instituut TNO (author)
This study was designed to investigate the potential antiatherosclerotic effects of the calcium antagonist amlodipine as compared with the HMG-CoA reductase inhibitor atorvastatin and the combination of both in ApoE*3-Leiden transgenic mice. Four groups of 15 ApoE*3-Leiden mice were put on a high-cholesterol diet. One group received 0.002% (wt...
article 2003
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Dhonukshe-Rutten, R.A.M. (author), Lips, M. (author), de Jong, N. (author), Marijke, J.M.C.A.P. (author), Hiddink, G.J. (author), van Dusseldorp, M. (author), de Groot, L.C.P.G.M. (author), van Staveren, W.A. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
Subclinical vitamin B-12 deficiency is common in the elderly. Encouraged by early indications, we investigated the plasma vitamin B-12 status in association with bone mineral content (BMC) and bone mineral density (BMD) in frail elderly people. Data of 194 free-living Dutch frail elderly (143 women and 51 men) were available. BMC and BMD were...
article 2003
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Tryfonidou, M.A. (author), Holl, M.S. (author), Stevenhagen, J.J. (author), Buurman, C.J. (author), Deluca, H.F. (author), Oosterlaken-Dijksterhuis, M.A. (author), van den Brom, W.E. (author), van Leeuwen, J.P.T.M. (author), Hazewinkel, H.A.W. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
The effects of excessive non-toxic dietary Vitamin D3 supplementation on Ca homeostasis with specific effects on endochondral ossification and skeletal remodeling were investigated in a group of growing Great Dane dogs supplemented with cholecalciferol (Vitamin D3; HVitD) versus a control group (CVitD) (1350 μg versus 11.4 μg Vitamin D3 per...
article 2003
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van Beek, E.R. (author), Cohen, L.H. (author), Leroy, I.M. (author), Ebetino, F.H. (author), Löwik, C.W.G.M. (author), Papapoulos, S.E. (author), Gaubius Instituut TNO (author)
Bisphosphonates (BPS) inhibit bone resorption and are divided into two classes according to their chemical structure and mechanism of action: nonnitrogen containing BPS such as etidronate and clodronate that are of low potency and inhibit osteoclast function via metabolism into toxic ATP-metabolites and nitrogen-containing BPS (NBPS), such as...
article 2003
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Besemer, A.C. (author), Jetten, J.M. (author), Slaghek, T.M. (author), TNO Voeding (author)
The improved tandem oxidation sequence of starch with the aim of developing, e.g. degradable co-builders suitable for laundry formulations as an alternative to the currently used polyacrylates is described. The tandem oxidation of starch starts with sodium periodate treatment of granular starch followed by oxidation of the dialdehyde product...
article 2003
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TNO Voeding (author), Venema, K. (author), van Nuenen, M.H.M.C. (author), van den Heuvel, E.G. (author), Pool, W. (author), van der Vossen, J.M.B.M. (author)
The objective of this study was to compare the in vivo effect of lactulose on faecal parameters with the effect in a dynamic, computer-controlled in vitro model of the proximal large intestine (TIM-2). Faecal samples from 10 human volunteers collected before (non-adapted) and after 1 week of treatment (10 g/day) with lactulose (lactulose-adapted...
article 2003
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van Marken Lichtenbelt, W. (author), Daanen, H.A.M. (author)
Purpose of review Cold response can be insulative (drop in peripheral temperature) or metabolic (increase in energy expenditure). Nonshivering thermogenesis by sympathetic, norepinephrine-induced mitochondrial heat production in brown adipose tissue is a well known component of this metabolic response in infants and several animal species. In...
article 2003
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Hambly, R.J. (author), Saunders, M. (author), Rijken, P.J. (author), Rowland, I.R. (author), Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author)
Although there is much epidemiological evidence for an interaction between diet and colorectal cancer risk, the mechanisms by which diet might protect against colorectal cancer are still unclear. Here we report the significant up-regulation of carcinogen-induced apoptosis in the colon of rats fed a diet containing low-risk factors for colon...
article 2002
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Brama, P.A.J. (author), TeKoppele, J.M. (author), Bank, R.A. (author), Barneveld, A. (author), van Weeren, P.R. (author), Gaubius instituut TNO (author)
Subchondral bone provides structural support to the overlying articular cartilage, and plays an important role in osteochondral diseases. There is growing insight that the mechanical features of bone are related to the biochemistry of the collagen network and the mineral content. In the present study, part of the normal developmental process and...
article 2002
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Tryfonidou, M.A. (author), Stevenhagen, J.J. (author), van den Bemd, G.J.C.M. (author), Oosterlaken-Dijksterhuis, M.A. (author), Deluca, H.F. (author), Mol, J.A. (author), van den Brom, W.E. (author), van Leeuwen, J.P.T.M. (author), Hazewinkel, H.A.W. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Hormonal regulation of calcium (Ca) absorption was investigated in a cholecalciferol (vitamin D3)supplemented group (hVitD) vs. a control group (cVitD) of growing Great Danes (100 vs. 12.5 μg vitamin D3/kg diet). Although Ca intakes did not differ, fractional Ca absorption was significantly lower in the hVitD group than in the cVitD group. There...
article 2002
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TNO Voeding Centraal Instituut voor Voedingsonderzoek TNO (author), Conesa, A. (author), Jeenes, D. (author), Archer, D.B. (author), van den Hondel, C.A.M.J.J. (author), Punt, P.J. (author)
Heme-containing peroxidases from white rot basidiomycetes, in contrast to most proteins of fungal origin, are poorly produced in industrial filamentous fungal strains. Factors limiting peroxidase production are believed to operate at the posttranslational level. In particular, insufficient availability of the prosthetic group which is required...
article 2002
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Schokker, E.P. (author), Dalgleish, D.G. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
Calcium-induced flocculation of caseinate-stabilized soybean oil-in- water emulsions in conditions of Couette flow was studied. A concentrated emulsion (20% oil, 0.5-2.0% sodium caseinate in 20 mM imidazole, pH 7) was diluted 20 times in buffer containing concentrations of CaCl2 between 9 and 17 mM and sheared at rates between 335 and 1340 s-1....
article 2000
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Wassen, M.H.M. (author), Lammens, J. (author), Tekoppele, J.M. (author), Sakkers, R.J.B. (author), Liu, Z. (author), Verbout, A.J. (author), Bank, R.A. (author)
Although >80% of the mineral in mammalian bone is present in the collagen fibrils, limited information is available about factors that determine a proper deposition of mineral. This study investigates whether a specific collagen matrix is required for fibril mineralization. Calcifying callus from dog tibias was obtained at various times (3-21...
article 2000
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van Nieuw Amerongen, G.P. (author), Delft, S.V. (author), Vermeer, M.A. (author), Collard, J.G. (author), van Hinsbergh, V.W.M. (author), Gaubius Instituut TNO (author)
Endothelial cells (ECs) actively regulate the extravasation of blood constituents. On stimulation by vasoactive agents and thrombin, ECs change their cytoskeletal architecture and small gaps are formed between neighboring cells. These changes partly depend on a rise in [Ca2+](i) and activation of the Ca2+/calmodulin-dependent myosin light chain...
article 2000
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van den Heuvel, E.G.H.M. (author), Schoterman, M.H.C. (author), Muijs, T. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
The aim of this study was to investigate whether a product rich in transgalactooligosaccharides (TOS, Elix'or) stimulates true Ca absorption in postmenopausal women. The study was a double-blind, randomized crossover study, consisting of two 9-d treatment periods separated by a 19-d washout period. During the treatment periods, 12 subjects drank...
article 2000
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Kampman, E. (author), Voskuil, D.W. (author), van Kraats, A.A. (author), Balder, H.F. (author), van Muijen, G.N.P. (author), Goldbohm, R.A. (author), van 't Veer, P. (author), Centraal Instituut voor Voedingsonderzoek TNO (author)
K-ras gene mutations (codons 12 and 13) were determined by PCR-based mutant allele-specific amplification (MASA) in tumour tissue of 185 colon cancer patients: 36% harboured mutations, of which 82% were located in codon 12. High intakes of animal protein, calcium and poultry were differently associated with codon 12 and 13 mutations: odds ratios...
article 2000
Searched for: subject%3A%22Calcium%22
(41 - 60 of 126)

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