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Andersen, Z.J. (author), Pedersen, M. (author), Weinmayr, G. (author), Stafoggia, M. (author), Galassi, C. (author), Jørgensen, J.T. (author), Sommar, J.N. (author), Forsberg, B. (author), Olsson, D. (author), Oftedal, B. (author), Aasvang, G.M. (author), Schwarze, P. (author), Pyko, A. (author), Pershagen, G. (author), Korek, M. (author), Faire, U.D. (author), Östenson, C.G. (author), Fratiglioni, L. (author), Eriksen, K.T. (author), Poulsen, A.H. (author), Tjønneland, A. (author), Braüner, E.V. (author), Peeters, P.H. (author), Bueno de Mesquita, B. (author), Jaensch, A. (author), Nagel, G. (author), Lang, A. (author), Wang, M. (author), Tsai, M.Y. (author), Grioni, S. (author), Marcon, A. (author), Krogh, V. (author), Ricceri, F. (author), Sacerdote, C. (author), Migliore, E. (author), Vermeulen, R. (author), Sokhi, R. (author), Keuken, M. (author), de Hoogh, K. (author), Beelen, R. (author), Vineis, P. (author), Cesaroni, G. (author), Brunekreef, B. (author), Hoek, G. (author), Raaschou-Nielsen, O. (author)Background. Epidemiological evidence on the association between ambient air pollution and brain tumor risk is sparse and inconsistent. Methods. In 12 cohorts from 6 European countries, individual estimates of annual mean air pollution levels at the baseline residence were estimated by standardized land-use regression models developed within the...article 2018
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End, C. (author), Bikker, F.J. (author), Renner, M. (author), Bergmann, G. (author), Lyer, S. (author), Blaich, S. (author), Hudler, M. (author), Helmke, B. (author), Gassler, N. (author), Autschbach, F. (author), Ligtenberg, A.J.M. (author), Benner, A. (author), Holmskov, U. (author), Schirmacher, P. (author), Nieuw Amerongen, A.V. (author), Rosenstiel, P. (author), Sina, C. (author), Franke, A. (author), Hafner, M. (author), Kioschis, P. (author), Schreiber, S. (author), Poustka, A. (author), Mollenhauer, J. (author)Deleted in malignant brain tumors 1 (DMBT1) is a secreted glycoprotein displaying a broad bacterial-binding spectrum. Recent functional and genetic studies linked DMBT1 to the suppression of LPS-induced TLR4-mediated NF-kappaB activation and to the pathogenesis of Crohn's disease. Here, we aimed at unraveling the molecular basis of its function...article 2009
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Bsibsi, M. (author), Bajramovic, J.J. (author), van Duijvenvoorden, E. (author), Persoon, C. (author), Ravid, R. (author), van Noort, J.M. (author), Vogt, M.H.J. (author), TNO Kwaliteit van Leven (author)Human astrocytes express a limited repertoire of Toll-like receptor (TLR) family members including TLR1-4, which are expressed on the cell surface. Also, TLR3 but not TLR4 activation on astrocytes induces expression of several factors involved in neuroprotection and down-regulation of inflammation rather than in the onset of traditional pro...article 2007
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Centraal Instituut voor Voedingsonderzoek TNO TNO Voeding (author), Woutersen, R.A. (author)Acrylonitrile is a monomer used extensively as a raw material in the manufacturing of acrylic fibers, plastics, synthetic rubbers, and acrylamide. It has been classified as a probable human carcinogen according to the results of numerous chronic rat bioassays. The present report summarizes the toxicity data on acrylonitrile and reviews available...article 1998